Slowed dynamics of thin filament regulatory units reduces Ca 2+-sensitivity of cardiac biomechanical function

Cellular and Molecular Bioengineering

Volumn 6, Issue 2, 2013, Pages 183-198

  Loong, Campion K P ^a,b,c   Takeda, Aya K ^a,d   Badr, Myriam A ^a   Rogers, Jordan S ^a,e   Chase, P Bryant ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

^b Florida State University   (United States)

^c MATHWORKS INC   (United States)

^d Genaris Inc   (Japan)

^e UNIVERSITY OF FLORIDA   (United States)

Author keywords

Actin; Disaccharide sucrose; In vitro motility assay; Kinetics of isometric tension redevelopment; Microviscosity; Monosaccharide glucose; Myosin; Skinned myocyte; Tropomyosin; Troponin

Indexed keywords

CALCIUM ION; GLUCOSE; MYOSIN ADENOSINE TRIPHOSPHATASE; SUCROSE; TROPOMYOSIN; TROPONIN;

ANIMAL CELL; ARTICLE; BIOMECHANICS; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL ASSAY; CELL MEMBRANE PERMEABILITY; CELL MOTILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE TENSION; IN VITRO STUDY; ISOMETRICS; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; MUSCLE ISOMETRIC CONTRACTION; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SOLVENT EFFECT; STEADY STATE; SWINE; THIN FILAMENT; VISCOSITY;

SUS;

EID: 84879506955     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-013-0269-8     Document Type: Article

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