메뉴 건너뛰기




Volumn 145, Issue 1, 2013, Pages 221-231

Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types

Author keywords

c MYC; Cancer Stem Cell; Cell of Origin; HCC

Indexed keywords

CYTOKERATIN 19; EPITHELIAL CELL ADHESION MOLECULE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; VIMENTIN;

EID: 84879494478     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2013.03.013     Document Type: Article
Times cited : (150)

References (48)
  • 1
    • 78751676408 scopus 로고    scopus 로고
    • Cells of origin in cancer
    • J.E. Visvader Cells of origin in cancer Nature 469 2011 314 322
    • (2011) Nature , vol.469 , pp. 314-322
    • Visvader, J.E.1
  • 2
    • 34547566701 scopus 로고    scopus 로고
    • Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes
    • T.A. Ince, A.L. Richardson, and G.W. Bell Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes Cancer Cell 12 2007 160 170
    • (2007) Cancer Cell , vol.12 , pp. 160-170
    • Ince, T.A.1    Richardson, A.L.2    Bell, G.W.3
  • 3
    • 79958761641 scopus 로고    scopus 로고
    • Cell of origin of small cell lung cancer: Inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung
    • K.D. Sutherland, N. Proost, and I. Brouns Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung Cancer Cell 19 2011 754 764
    • (2011) Cancer Cell , vol.19 , pp. 754-764
    • Sutherland, K.D.1    Proost, N.2    Brouns, I.3
  • 4
    • 79955631558 scopus 로고    scopus 로고
    • Genetics of hepatobiliary carcinogenesis
    • J.C. Nault, and J. Zucman-Rossi Genetics of hepatobiliary carcinogenesis Semin Liver Dis 31 2011 173 187
    • (2011) Semin Liver Dis , vol.31 , pp. 173-187
    • Nault, J.C.1    Zucman-Rossi, J.2
  • 5
    • 77956049820 scopus 로고    scopus 로고
    • Pathology of combined hepatocellular-cholangiocarcinoma
    • M.M. Yeh Pathology of combined hepatocellular-cholangiocarcinoma J Gastroenterol Hepatol 25 2010 1485 1492
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. 1485-1492
    • Yeh, M.M.1
  • 6
    • 33745533559 scopus 로고    scopus 로고
    • Liver stem cells and their implication in hepatocellular and cholangiocarcinoma
    • T. Roskams Liver stem cells and their implication in hepatocellular and cholangiocarcinoma Oncogene 25 2006 3818 3822
    • (2006) Oncogene , vol.25 , pp. 3818-3822
    • Roskams, T.1
  • 7
    • 77951037177 scopus 로고    scopus 로고
    • Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma
    • H.G. Woo, J.H. Lee, and J.H. Yoon Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma Cancer Res 70 2010 3034 3041
    • (2010) Cancer Res , vol.70 , pp. 3034-3041
    • Woo, H.G.1    Lee, J.H.2    Yoon, J.H.3
  • 8
    • 84858608410 scopus 로고    scopus 로고
    • Cancer stem cells: Impact, heterogeneity, and uncertainty
    • J.A. Magee, E. Piskounova, and S.J. Morrison Cancer stem cells: impact, heterogeneity, and uncertainty Cancer Cell 21 2012 283 296
    • (2012) Cancer Cell , vol.21 , pp. 283-296
    • Magee, J.A.1    Piskounova, E.2    Morrison, S.J.3
  • 9
    • 34249980343 scopus 로고    scopus 로고
    • Identification and characterization of tumorigenic liver cancer stem/progenitor cells
    • S. Ma, K.W. Chan, and L. Hu Identification and characterization of tumorigenic liver cancer stem/progenitor cells Gastroenterology 132 2007 2542 2556
    • (2007) Gastroenterology , vol.132 , pp. 2542-2556
    • Ma, S.1    Chan, K.W.2    Hu, L.3
  • 10
    • 80052031109 scopus 로고    scopus 로고
    • Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways
    • J.U. Marquardt, C. Raggi, and J.B. Andersen Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways Hepatology 54 2011 1031 1042
    • (2011) Hepatology , vol.54 , pp. 1031-1042
    • Marquardt, J.U.1    Raggi, C.2    Andersen, J.B.3
  • 11
    • 84859153211 scopus 로고    scopus 로고
    • Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice
    • T. Ishikawa, V.M. Factor, and J.U. Marquardt Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice Hepatology 55 2012 1215 1226
    • (2012) Hepatology , vol.55 , pp. 1215-1226
    • Ishikawa, T.1    Factor, V.M.2    Marquardt, J.U.3
  • 12
    • 84860530018 scopus 로고    scopus 로고
    • Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells
    • S.B. Lee, D. Seo, and D. Choi Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells Stem Cells 30 2012 997 1007
    • (2012) Stem Cells , vol.30 , pp. 997-1007
    • Lee, S.B.1    Seo, D.2    Choi, D.3
  • 13
    • 0029968624 scopus 로고    scopus 로고
    • Reduced growth capacity of hepatocytes from c-myc and c-myc/TGF-alpha transgenic mice in primary culture
    • C.Y. Kao, V.M. Factor, and S.S. Thorgeirsson Reduced growth capacity of hepatocytes from c-myc and c-myc/TGF-alpha transgenic mice in primary culture Biochem Biophys Res Commun 222 1996 64 70
    • (1996) Biochem Biophys Res Commun , vol.222 , pp. 64-70
    • Kao, C.Y.1    Factor, V.M.2    Thorgeirsson, S.S.3
  • 14
    • 75149150660 scopus 로고    scopus 로고
    • HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
    • C.J. David, M. Chen, and M. Assanah HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer Nature 463 2010 364 368
    • (2010) Nature , vol.463 , pp. 364-368
    • David, C.J.1    Chen, M.2    Assanah, M.3
  • 15
    • 0028122926 scopus 로고
    • Origin and fate of oval cells in dipin-induced hepatocarcinogenesis in the mouse
    • V.M. Factor, S.A. Radaeva, and S.S. Thorgeirsson Origin and fate of oval cells in dipin-induced hepatocarcinogenesis in the mouse Am J Pathol 145 1994 409 422
    • (1994) Am J Pathol , vol.145 , pp. 409-422
    • Factor, V.M.1    Radaeva, S.A.2    Thorgeirsson, S.S.3
  • 16
    • 0021912710 scopus 로고
    • Expression of c-Ki-ras, c-Ha-ras, and c-myc in specific cell types during hepatocarcinogenesis
    • P. Yaswen, M. Goyette, and P.R. Shank Expression of c-Ki-ras, c-Ha-ras, and c-myc in specific cell types during hepatocarcinogenesis Mol Cell Biol 5 1985 780 786
    • (1985) Mol Cell Biol , vol.5 , pp. 780-786
    • Yaswen, P.1    Goyette, M.2    Shank, P.R.3
  • 17
    • 33645976174 scopus 로고    scopus 로고
    • Ubiquitous activation of Ras and Jak/Stat pathways in human HCC
    • D.F. Calvisi, S. Ladu, and A. Gorden Ubiquitous activation of Ras and Jak/Stat pathways in human HCC Gastroenterology 130 2006 1117 1128
    • (2006) Gastroenterology , vol.130 , pp. 1117-1128
    • Calvisi, D.F.1    Ladu, S.2    Gorden, A.3
  • 18
    • 33745924696 scopus 로고    scopus 로고
    • Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties
    • T. Chiba, K. Kita, and Y.W. Zheng Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties Hepatology 44 2006 240 251
    • (2006) Hepatology , vol.44 , pp. 240-251
    • Chiba, T.1    Kita, K.2    Zheng, Y.W.3
  • 19
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • S.A. Mani, W. Guo, and M.J. Liao The epithelial-mesenchymal transition generates cells with properties of stem cells Cell 133 2008 704 715
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3
  • 20
    • 68349094342 scopus 로고    scopus 로고
    • Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver
    • M. Okabe, Y. Tsukahara, and M. Tanaka Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver Development 136 2009 1951 1960
    • (2009) Development , vol.136 , pp. 1951-1960
    • Okabe, M.1    Tsukahara, Y.2    Tanaka, M.3
  • 21
    • 18744377702 scopus 로고    scopus 로고
    • The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis
    • L. Xin, D.A. Lawson, and O.N. Witte The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis Proc Natl Acad Sci U S A 102 2005 6942 6947
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 6942-6947
    • Xin, L.1    Lawson, D.A.2    Witte, O.N.3
  • 22
    • 0035072771 scopus 로고    scopus 로고
    • Origin and structural evolution of the early proliferating oval cells in rat liver
    • S. Paku, J. Schnur, and P. Nagy Origin and structural evolution of the early proliferating oval cells in rat liver Am J Pathol 158 2001 1313 1323
    • (2001) Am J Pathol , vol.158 , pp. 1313-1323
    • Paku, S.1    Schnur, J.2    Nagy, P.3
  • 23
    • 77951728697 scopus 로고    scopus 로고
    • Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver
    • S. Lorenzini, T.G. Bird, and L. Boulter Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver Gut 59 2010 645 654
    • (2010) Gut , vol.59 , pp. 645-654
    • Lorenzini, S.1    Bird, T.G.2    Boulter, L.3
  • 24
    • 73949140059 scopus 로고    scopus 로고
    • A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
    • L. Madisen, T.A. Zwingman, and S.M. Sunkin A robust and high-throughput Cre reporting and characterization system for the whole mouse brain Nat Neurosci 13 2010 133 140
    • (2010) Nat Neurosci , vol.13 , pp. 133-140
    • Madisen, L.1    Zwingman, T.A.2    Sunkin, S.M.3
  • 25
    • 0033867635 scopus 로고    scopus 로고
    • Hepatic polyploidy and liver growth control
    • S. Gupta Hepatic polyploidy and liver growth control Semin Cancer Biol 10 2000 161 171
    • (2000) Semin Cancer Biol , vol.10 , pp. 161-171
    • Gupta, S.1
  • 26
    • 84861560298 scopus 로고    scopus 로고
    • A fibrous stromal component in hepatocellular carcinoma reveals a cholangiocarcinoma-like gene expression trait and epithelial-mesenchymal transition
    • J.Y. Seok, D.C. Na, and H.G. Woo A fibrous stromal component in hepatocellular carcinoma reveals a cholangiocarcinoma-like gene expression trait and epithelial-mesenchymal transition Hepatology 55 2012 1776 1786
    • (2012) Hepatology , vol.55 , pp. 1776-1786
    • Seok, J.Y.1    Na, D.C.2    Woo, H.G.3
  • 27
    • 0034090310 scopus 로고    scopus 로고
    • Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
    • J. Li, G. Ning, and S.A. Duncan Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha Genes Dev 14 2000 464 474
    • (2000) Genes Dev , vol.14 , pp. 464-474
    • Li, J.1    Ning, G.2    Duncan, S.A.3
  • 29
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • A. Subramanian, P. Tamayo, and V.K. Mootha Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles Proc Natl Acad Sci U S A 102 2005 15545 15550
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3
  • 30
    • 34248223535 scopus 로고    scopus 로고
    • A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis
    • S.R. Alonso, L. Tracey, and P. Ortiz A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis Cancer Res 67 2007 3450 3460
    • (2007) Cancer Res , vol.67 , pp. 3450-3460
    • Alonso, S.R.1    Tracey, L.2    Ortiz, P.3
  • 31
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • K. Kim, A. Doi, and B. Wen Epigenetic memory in induced pluripotent stem cells Nature 467 2010 285 290
    • (2010) Nature , vol.467 , pp. 285-290
    • Kim, K.1    Doi, A.2    Wen, B.3
  • 32
    • 85027958626 scopus 로고    scopus 로고
    • Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
    • Y. Ohi, H. Qin, and C. Hong Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells Nat Cell Biol 13 2011 541 549
    • (2011) Nat Cell Biol , vol.13 , pp. 541-549
    • Ohi, Y.1    Qin, H.2    Hong, C.3
  • 33
    • 41449118521 scopus 로고    scopus 로고
    • Module map of stem cell genes guides creation of epithelial cancer stem cells
    • D.J. Wong, H. Liu, and T.W. Ridky Module map of stem cell genes guides creation of epithelial cancer stem cells Cell Stem Cell 2 2008 333 344
    • (2008) Cell Stem Cell , vol.2 , pp. 333-344
    • Wong, D.J.1    Liu, H.2    Ridky, T.W.3
  • 34
    • 77957757417 scopus 로고    scopus 로고
    • A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
    • J. Kim, A.J. Woo, and J. Chu A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs Cell 143 2010 313 324
    • (2010) Cell , vol.143 , pp. 313-324
    • Kim, J.1    Woo, A.J.2    Chu, J.3
  • 35
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • I. Ben-Porath, M.W. Thomson, and V.J. Carey An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors Nat Genet 40 2008 499 507
    • (2008) Nat Genet , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3
  • 36
    • 33746441453 scopus 로고    scopus 로고
    • Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors
    • L. Zender, W. Xue, and C. Cordon-Cardo Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors Cold Spring Harb Symp Quant Biol 70 2005 251 261
    • (2005) Cold Spring Harb Symp Quant Biol , vol.70 , pp. 251-261
    • Zender, L.1    Xue, W.2    Cordon-Cardo, C.3
  • 37
    • 1942487260 scopus 로고    scopus 로고
    • Morphological changes of early human hepatocarcinogenesis
    • P. Hytiroglou Morphological changes of early human hepatocarcinogenesis Semin Liver Dis 24 2004 65 75
    • (2004) Semin Liver Dis , vol.24 , pp. 65-75
    • Hytiroglou, P.1
  • 38
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • K. Polyak, and R.A. Weinberg Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits Nat Rev Cancer 9 2009 265 273
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 39
    • 79956351015 scopus 로고    scopus 로고
    • Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
    • C.L. Chaffer, I. Brueckmann, and C. Scheel Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state Proc Natl Acad Sci U S A 108 2011 7950 7955
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 7950-7955
    • Chaffer, C.L.1    Brueckmann, I.2    Scheel, C.3
  • 40
    • 80052431169 scopus 로고    scopus 로고
    • In vitro generation of human cells with cancer stem cell properties
    • P. Scaffidi, and T. Misteli In vitro generation of human cells with cancer stem cell properties Nat Cell Biol 13 2011 1051 1061
    • (2011) Nat Cell Biol , vol.13 , pp. 1051-1061
    • Scaffidi, P.1    Misteli, T.2
  • 41
    • 79960032630 scopus 로고    scopus 로고
    • Cell of origin in AML: Susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex
    • M. Heuser, H. Yun, and T. Berg Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex Cancer Cell 20 2011 39 52
    • (2011) Cancer Cell , vol.20 , pp. 39-52
    • Heuser, M.1    Yun, H.2    Berg, T.3
  • 42
    • 11244287542 scopus 로고    scopus 로고
    • Dose-dependent inhibition of thyroid differentiation by RAS oncogenes
    • G. De Vita, L. Bauer, and V.M. da Costa Dose-dependent inhibition of thyroid differentiation by RAS oncogenes Mol Endocrinol 19 2005 76 89
    • (2005) Mol Endocrinol , vol.19 , pp. 76-89
    • De Vita, G.1    Bauer, L.2    Da Costa, V.M.3
  • 43
    • 84868224979 scopus 로고    scopus 로고
    • Multiple roles of p53 related pathways in somatic cell reprogramming and stem cell differentiation
    • L. Yi, C. Lu, and W. Hu Multiple roles of p53 related pathways in somatic cell reprogramming and stem cell differentiation Cancer Res 72 2012 5635 5645
    • (2012) Cancer Res , vol.72 , pp. 5635-5645
    • Yi, L.1    Lu, C.2    Hu, W.3
  • 44
    • 84861534766 scopus 로고    scopus 로고
    • Histological diversity in cholangiocellular carcinoma reflects the different cholangiocyte phenotypes
    • M. Komuta, O. Govaere, and V. Vandecaveye Histological diversity in cholangiocellular carcinoma reflects the different cholangiocyte phenotypes Hepatology 55 2012 1876 1888
    • (2012) Hepatology , vol.55 , pp. 1876-1888
    • Komuta, M.1    Govaere, O.2    Vandecaveye, V.3
  • 45
    • 84864773126 scopus 로고    scopus 로고
    • Cholangiocarcinomas can originate from hepatocytes in mice
    • B. Fan, Y. Malato, and D.F. Calvisi Cholangiocarcinomas can originate from hepatocytes in mice J Clin Invest 122 2012 2911 2915
    • (2012) J Clin Invest , vol.122 , pp. 2911-2915
    • Fan, B.1    Malato, Y.2    Calvisi, D.F.3
  • 46
    • 33748199553 scopus 로고    scopus 로고
    • Conditional transgenic models define how MYC initiates and maintains tumorigenesis
    • C. Arvanitis, and D.W. Felsher Conditional transgenic models define how MYC initiates and maintains tumorigenesis Semin Cancer Biol 16 2006 313 317
    • (2006) Semin Cancer Biol , vol.16 , pp. 313-317
    • Arvanitis, C.1    Felsher, D.W.2
  • 47
    • 66149152693 scopus 로고    scopus 로고
    • Central role of c-Myc during malignant conversion in human hepatocarcinogenesis
    • P. Kaposi-Novak, L. Libbrecht, and H.G. Woo Central role of c-Myc during malignant conversion in human hepatocarcinogenesis Cancer Res 69 2009 2775 2782
    • (2009) Cancer Res , vol.69 , pp. 2775-2782
    • Kaposi-Novak, P.1    Libbrecht, L.2    Woo, H.G.3
  • 48
    • 7744220635 scopus 로고    scopus 로고
    • MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
    • C.M. Shachaf, A.M. Kopelman, and C. Arvanitis MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer Nature 431 2004 1112 1127
    • (2004) Nature , vol.431 , pp. 1112-1127
    • Shachaf, C.M.1    Kopelman, A.M.2    Arvanitis, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.