메뉴 건너뛰기




Volumn 18, Issue 6, 2013, Pages 640-643

Personalized medicine: Hype or reality

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; BCR ABL PROTEIN; BIOLOGICAL MARKER; CRIZOTINIB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; K RAS PROTEIN; LAPATINIB; PHOSPHATIDYLINOSITOL 3 KINASE; TRASTUZUMAB; VEMURAFENIB;

EID: 84879493413     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2013-0210     Document Type: Editorial
Times cited : (8)

References (24)
  • 1
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER 2 for metastatic breast cancer that overexpresses HER2
    • Slamon DF, Leyland-Jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER 2 for metastatic breast cancer that overexpresses HER2. N Eng J Med 2001; 344: 783792.
    • (2001) N Eng J Med , vol.344 , pp. 783792
    • Slamon, D.F.1    Leyland-Jones, B.2    Shak, S.3
  • 2
    • 0037103424 scopus 로고    scopus 로고
    • Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
    • 472-280
    • Demetri GD, Margaret von Mehren, Blanke CD et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 347;472-280.
    • N Engl J Med , vol.347
    • Demetri, G.D.1    von Mehren, M.2    Blanke, C.D.3
  • 3
    • 58149398623 scopus 로고    scopus 로고
    • Translation of the Philadelphia chromosome into therapy for CML
    • Druker BJ. Translation of the Philadelphia chromosome into therapy for CML. Blood 2008; 112:4808-4817.
    • (2008) Blood , vol.112 , pp. 4808-4817
    • Druker, B.J.1
  • 4
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • New drugs
    • Flaherty KT, Puzanov I, Kim KB et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med. 2010;363:809-19New drugs
    • (2010) N Engl J Med. , vol.363 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3
  • 6
    • 84894890948 scopus 로고    scopus 로고
    • http://www.fda.gov/drugs/lnformationon-drugs/Approved
  • 7
    • 84861730960 scopus 로고    scopus 로고
    • Molecular prescreening to select patient population in early clinical trials
    • 1038/nrclinonc. 2012.48
    • Rudon J, Saura C, Dienstmann R et al. Molecular prescreening to select patient population in early clinical trials. Nat. Rev Clinical Oncol 2012; 1038/nrclinonc. 2012.48.
    • (2012) Nat. Rev Clinical Oncol
    • Rudon, J.1    Saura, C.2    Dienstmann, R.3
  • 8
    • 84869462031 scopus 로고    scopus 로고
    • Crizotinib for the treatment of ALK-rearranged non-small cell lung cancer: A success story to usher in the second decade of molecular targeted therapy in oncology
    • Ou S-H, Bartlett CH, Mino-Kenudson M et. al. Crizotinib for the treatment of ALK-rearranged non-small cell lung cancer: A success story to usher in the second decade of molecular targeted therapy in oncology. The Oncologist 2012; 17:1351-1375.
    • (2012) The Oncologist , vol.17 , pp. 1351-1375
    • Ou, S.-H.1    Bartlett, C.H.2    Mino-Kenudson, M.3
  • 9
    • 78651071913 scopus 로고    scopus 로고
    • Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping
    • Arcila M, Lau C, Nafa K et al. Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping. J Mol Diagn. 2011;13:64-73.
    • (2011) J Mol Diagn. , vol.13 , pp. 64-73
    • Arcila, M.1    Lau, C.2    Nafa, K.3
  • 10
    • 84879495878 scopus 로고    scopus 로고
    • ROS1 Rearrangements define a unique molecular class of lung cancers
    • Epub 2012 Jan 3
    • Bergethon K, Shaw AT, Ou S-H I et al. ROS1 Rearrangements define a unique molecular class of lung cancers. J Clin Oncol 2012; 35: 6345, Epub 2012 Jan 3.
    • (2012) J Clin Oncol , vol.35 , pp. 6345
    • Bergethon, K.1    Shaw, A.T.2    Ou, S.-H.I.3
  • 11
    • 84873027952 scopus 로고    scopus 로고
    • Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer; interaction of EGFR ligand expression with RAS/RAF, PI3KCAgenotypes
    • Feb 2, doi: 10.1186/1471-2407-13-49
    • Pentheroudakis G, Kotoula V, De Roock W et. al. Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer; interaction of EGFR ligand expression with RAS/RAF, PI3KCAgenotypes. BMC Cancer 2013 Feb 2;13:49. doi: 10.1186/1471-2407-13-49.
    • (2013) BMC Cancer , vol.13 , pp. 49
    • Pentheroudakis, G.1    Kotoula, V.2    de Roock, W.3
  • 12
    • 84890546714 scopus 로고    scopus 로고
    • New York Times. Published April 21,. Available at, Accessed June 3, 2013
    • Hartocollis, Anemona. Cancer centers racing to map patients' genes. New York Times. Published April 21, 2013. Available at http:// www.nytimes.com/2013/0 4/22/health/ patients-genes-seen-as-future-of-cancer-care. html?pagewanted=all&_r=0. Accessed June 3, 2013.
    • (2013) Cancer centers racing to map patients' genes
    • Hartocollis, A.1
  • 13
    • 84894883457 scopus 로고    scopus 로고
    • Crizotinib versus chemotherapy in advanced ALK-rear-ranged lung cancer
    • Shaw A, Kim D-W, Nakagawa K et. al. Crizotinib versus chemotherapy in advanced ALK-rear-ranged lung cancer. N Engl J Med doi
    • N Engl J Med doi
    • Shaw, A.1    Kim, D.-W.2    Nakagawa, K.3
  • 14
    • 77953930730 scopus 로고    scopus 로고
    • Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
    • Maemondo M, Inoue A, Kobayashi K et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010;24:2380-8.
    • (2010) N Engl J Med , vol.24 , pp. 2380-2388
    • Maemondo, M.1    Inoue, A.2    Kobayashi, K.3
  • 15
    • 84879467352 scopus 로고    scopus 로고
    • The Northern Ireland Molecular Pathology L aboratory Available at, Accessed June 3
    • The Northern Ireland Molecular Pathology L aboratory. Available at https://vimeo. com/55830092. Accessed June 3, 2013.
  • 16
    • 84879487505 scopus 로고    scopus 로고
    • Published March 26,. Accessed June 3, 2013
    • Hollmer, Mark. U.K.'s NHSdebuts multi-gene sequencing cancer Dx. http://www.fiercemedi-caldevices.com/story/uk-nhs-debuts-multi-gene-sequencing-cancer-dx. Published March 26, 2013. Accessed June 3, 2013.
    • (2013) U.K.'s NHSdebuts multi-gene sequencing cancer Dx
    • Hollmer, M.1
  • 17
    • 84879472127 scopus 로고    scopus 로고
    • France puts €260 million into research infrastructure
    • Published online 8 March. Available at, Accessed June 3, 2013
    • Butler, Declan. France puts €260 million into research infrastructure. Nature. Published online 8 March 2011. Available at: http://www.nature. com/news/2011/110308/full/news.2011.145.html. Accessed June 3, 2013.
    • (2011) Nature
    • Butler, D.1
  • 18
    • 84879496363 scopus 로고    scopus 로고
    • German Cancer Research Center, Published April 15,. Available at, Accessed June 3, 2013
    • German Cancer Research Center. Joining forces against cancer-German consortium for translational cancer research gets started. Published April 15, 2011. Available at: http://www. dkfz.de/en/presse/pressemitteilungen/2011/ dkfz-pm-11-24-German-Consortium-for-Trans-lational-Cancer-Research-Gets-Started.php. Accessed June 3, 2013.
    • (2011) Joining forces against cancer-German consortium for translational cancer research gets started
  • 19
    • 84879474421 scopus 로고    scopus 로고
    • Cancer Prevention and Research Institute of Texas Available at, 2013, Accessed June 3
    • Cancer Prevention and Research Institute of Texas. Available at: http://www.cprit.state.tx.us. Accessed June 3, 2013.
  • 20
    • 84879474648 scopus 로고    scopus 로고
    • Published January 29,. Available at, Accessed June 3, 2013
    • Copelin, Laylan. CPRIT fallout: Cancer network ceases operations. Published January 29, 2013. Available at: http://www.statesman.com/ news/business/cprit-fallout-clinical-trials-net-work-suspends-ope/nT9SH/. Accessed June 3, 2013.
    • (2013) CPRIT fallout: Cancer network ceases operations
    • Copelin, L.1
  • 21
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-esopha-geal junction cancer (To GA): A phase 3, open-label randomized controlled trial
    • Bang Y-J, Van Cutsem E, Feyereislova et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-esopha-geal junction cancer (To GA): a phase 3, open-label randomized controlled trial. Lancet 2010;376, 687-697.
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.-J.1    van Cutsem, E.2    Feyereislova3
  • 22
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sondella R, et. al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-2139.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sondella, R.3
  • 23
    • 59449085455 scopus 로고    scopus 로고
    • Imatinib targeting of KIT-mutant oncoprotein in melanoma
    • Jiang X, Zhou J, Yuen NK, et. al. Imatinib targeting of KIT-mutant oncoprotein in melanoma. Clin Cancer Res 2008; 14: 7726-32.
    • (2008) Clin Cancer Res , vol.14 , pp. 7726-7732
    • Jiang, X.1    Zhou, J.2    Yuen, N.K.3
  • 24
    • 84870012939 scopus 로고    scopus 로고
    • Pona-tinib in refractory Philadelphia chromosome-positive leukemias
    • Cortes JE, Kantarjian H, Shah NP, et. al. Pona-tinib in refractory Philadelphia chromosome-positive leukemias. N Engl J. Med 2012; 367;2075-2088.
    • (2012) N Engl J. Med , vol.367 , pp. 2075-2088
    • Cortes, J.E.1    Kantarjian, H.2    Shah, N.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.