-
1
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER 2 for metastatic breast cancer that overexpresses HER2
-
Slamon DF, Leyland-Jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER 2 for metastatic breast cancer that overexpresses HER2. N Eng J Med 2001; 344: 783792.
-
(2001)
N Eng J Med
, vol.344
, pp. 783792
-
-
Slamon, D.F.1
Leyland-Jones, B.2
Shak, S.3
-
2
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
472-280
-
Demetri GD, Margaret von Mehren, Blanke CD et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 347;472-280.
-
N Engl J Med
, vol.347
-
-
Demetri, G.D.1
von Mehren, M.2
Blanke, C.D.3
-
3
-
-
58149398623
-
Translation of the Philadelphia chromosome into therapy for CML
-
Druker BJ. Translation of the Philadelphia chromosome into therapy for CML. Blood 2008; 112:4808-4817.
-
(2008)
Blood
, vol.112
, pp. 4808-4817
-
-
Druker, B.J.1
-
4
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
New drugs
-
Flaherty KT, Puzanov I, Kim KB et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med. 2010;363:809-19New drugs
-
(2010)
N Engl J Med.
, vol.363
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
-
6
-
-
84894890948
-
-
http://www.fda.gov/drugs/lnformationon-drugs/Approved
-
-
-
-
7
-
-
84861730960
-
Molecular prescreening to select patient population in early clinical trials
-
1038/nrclinonc. 2012.48
-
Rudon J, Saura C, Dienstmann R et al. Molecular prescreening to select patient population in early clinical trials. Nat. Rev Clinical Oncol 2012; 1038/nrclinonc. 2012.48.
-
(2012)
Nat. Rev Clinical Oncol
-
-
Rudon, J.1
Saura, C.2
Dienstmann, R.3
-
8
-
-
84869462031
-
Crizotinib for the treatment of ALK-rearranged non-small cell lung cancer: A success story to usher in the second decade of molecular targeted therapy in oncology
-
Ou S-H, Bartlett CH, Mino-Kenudson M et. al. Crizotinib for the treatment of ALK-rearranged non-small cell lung cancer: A success story to usher in the second decade of molecular targeted therapy in oncology. The Oncologist 2012; 17:1351-1375.
-
(2012)
The Oncologist
, vol.17
, pp. 1351-1375
-
-
Ou, S.-H.1
Bartlett, C.H.2
Mino-Kenudson, M.3
-
9
-
-
78651071913
-
Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping
-
Arcila M, Lau C, Nafa K et al. Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping. J Mol Diagn. 2011;13:64-73.
-
(2011)
J Mol Diagn.
, vol.13
, pp. 64-73
-
-
Arcila, M.1
Lau, C.2
Nafa, K.3
-
10
-
-
84879495878
-
ROS1 Rearrangements define a unique molecular class of lung cancers
-
Epub 2012 Jan 3
-
Bergethon K, Shaw AT, Ou S-H I et al. ROS1 Rearrangements define a unique molecular class of lung cancers. J Clin Oncol 2012; 35: 6345, Epub 2012 Jan 3.
-
(2012)
J Clin Oncol
, vol.35
, pp. 6345
-
-
Bergethon, K.1
Shaw, A.T.2
Ou, S.-H.I.3
-
11
-
-
84873027952
-
Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer; interaction of EGFR ligand expression with RAS/RAF, PI3KCAgenotypes
-
Feb 2, doi: 10.1186/1471-2407-13-49
-
Pentheroudakis G, Kotoula V, De Roock W et. al. Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer; interaction of EGFR ligand expression with RAS/RAF, PI3KCAgenotypes. BMC Cancer 2013 Feb 2;13:49. doi: 10.1186/1471-2407-13-49.
-
(2013)
BMC Cancer
, vol.13
, pp. 49
-
-
Pentheroudakis, G.1
Kotoula, V.2
de Roock, W.3
-
12
-
-
84890546714
-
-
New York Times. Published April 21,. Available at, Accessed June 3, 2013
-
Hartocollis, Anemona. Cancer centers racing to map patients' genes. New York Times. Published April 21, 2013. Available at http:// www.nytimes.com/2013/0 4/22/health/ patients-genes-seen-as-future-of-cancer-care. html?pagewanted=all&_r=0. Accessed June 3, 2013.
-
(2013)
Cancer centers racing to map patients' genes
-
-
Hartocollis, A.1
-
13
-
-
84894883457
-
Crizotinib versus chemotherapy in advanced ALK-rear-ranged lung cancer
-
Shaw A, Kim D-W, Nakagawa K et. al. Crizotinib versus chemotherapy in advanced ALK-rear-ranged lung cancer. N Engl J Med doi
-
N Engl J Med doi
-
-
Shaw, A.1
Kim, D.-W.2
Nakagawa, K.3
-
14
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo M, Inoue A, Kobayashi K et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010;24:2380-8.
-
(2010)
N Engl J Med
, vol.24
, pp. 2380-2388
-
-
Maemondo, M.1
Inoue, A.2
Kobayashi, K.3
-
15
-
-
84879467352
-
-
The Northern Ireland Molecular Pathology L aboratory Available at, Accessed June 3
-
The Northern Ireland Molecular Pathology L aboratory. Available at https://vimeo. com/55830092. Accessed June 3, 2013.
-
-
-
-
16
-
-
84879487505
-
-
Published March 26,. Accessed June 3, 2013
-
Hollmer, Mark. U.K.'s NHSdebuts multi-gene sequencing cancer Dx. http://www.fiercemedi-caldevices.com/story/uk-nhs-debuts-multi-gene-sequencing-cancer-dx. Published March 26, 2013. Accessed June 3, 2013.
-
(2013)
U.K.'s NHSdebuts multi-gene sequencing cancer Dx
-
-
Hollmer, M.1
-
17
-
-
84879472127
-
France puts €260 million into research infrastructure
-
Published online 8 March. Available at, Accessed June 3, 2013
-
Butler, Declan. France puts €260 million into research infrastructure. Nature. Published online 8 March 2011. Available at: http://www.nature. com/news/2011/110308/full/news.2011.145.html. Accessed June 3, 2013.
-
(2011)
Nature
-
-
Butler, D.1
-
18
-
-
84879496363
-
-
German Cancer Research Center, Published April 15,. Available at, Accessed June 3, 2013
-
German Cancer Research Center. Joining forces against cancer-German consortium for translational cancer research gets started. Published April 15, 2011. Available at: http://www. dkfz.de/en/presse/pressemitteilungen/2011/ dkfz-pm-11-24-German-Consortium-for-Trans-lational-Cancer-Research-Gets-Started.php. Accessed June 3, 2013.
-
(2011)
Joining forces against cancer-German consortium for translational cancer research gets started
-
-
-
19
-
-
84879474421
-
-
Cancer Prevention and Research Institute of Texas Available at, 2013, Accessed June 3
-
Cancer Prevention and Research Institute of Texas. Available at: http://www.cprit.state.tx.us. Accessed June 3, 2013.
-
-
-
-
20
-
-
84879474648
-
-
Published January 29,. Available at, Accessed June 3, 2013
-
Copelin, Laylan. CPRIT fallout: Cancer network ceases operations. Published January 29, 2013. Available at: http://www.statesman.com/ news/business/cprit-fallout-clinical-trials-net-work-suspends-ope/nT9SH/. Accessed June 3, 2013.
-
(2013)
CPRIT fallout: Cancer network ceases operations
-
-
Copelin, L.1
-
21
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-esopha-geal junction cancer (To GA): A phase 3, open-label randomized controlled trial
-
Bang Y-J, Van Cutsem E, Feyereislova et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-esopha-geal junction cancer (To GA): a phase 3, open-label randomized controlled trial. Lancet 2010;376, 687-697.
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.-J.1
van Cutsem, E.2
Feyereislova3
-
22
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sondella R, et. al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sondella, R.3
-
23
-
-
59449085455
-
Imatinib targeting of KIT-mutant oncoprotein in melanoma
-
Jiang X, Zhou J, Yuen NK, et. al. Imatinib targeting of KIT-mutant oncoprotein in melanoma. Clin Cancer Res 2008; 14: 7726-32.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7726-7732
-
-
Jiang, X.1
Zhou, J.2
Yuen, N.K.3
-
24
-
-
84870012939
-
Pona-tinib in refractory Philadelphia chromosome-positive leukemias
-
Cortes JE, Kantarjian H, Shah NP, et. al. Pona-tinib in refractory Philadelphia chromosome-positive leukemias. N Engl J. Med 2012; 367;2075-2088.
-
(2012)
N Engl J. Med
, vol.367
, pp. 2075-2088
-
-
Cortes, J.E.1
Kantarjian, H.2
Shah, N.P.3
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