Combined antihypertensive therapy and sexual dysfunction: Terra incognita

Cardiology (Switzerland)

Volumn 125, Issue 4, 2013, Pages 232-234

  Doumas, M ^a,b,e   Viigimaa, M ^d   Papademetriou, V ^c  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b GEORGE WASHINGTON UNIVERSITY   (United States)

^c GEORGETOWN UNIVERSITY   (United States)

^d TALLINN UNIVERSITY OF TECHNOLOGY   (Estonia)

^e NONE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; FELODIPINE; IRBESARTAN; METOPROLOL; NEBIVOLOL; CHLORTALIDONE;

ANTIHYPERTENSIVE THERAPY; CORONARY ARTERY DISEASE; ERECTILE DYSFUNCTION; FEMALE SEXUAL DYSFUNCTION; FOLLOW UP; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; MONOTHERAPY; NOTE; PREVALENCE; PRIORITY JOURNAL; QUALITY OF LIFE; SEXUAL DYSFUNCTION; SEXUALITY; EDITORIAL; OXIDATIVE STRESS;

ANTIHYPERTENSIVE AGENTS; BIPHENYL COMPOUNDS; ERECTILE DYSFUNCTION; FELODIPINE; HUMANS; MALE; METOPROLOL; TETRAZOLES;

EID: 84879477648     PISSN: 00086312     EISSN: 14219751     Source Type: Journal    
DOI: 10.1159/000351696     Document Type: Note

References (19)

1. Doumas M, Tsakiris A, Douma S, et al: Factors affecting the increased prevalence of erectile dysfunction in Greek hypertensive compared with normotensive subjects. J Androl 2006; 27: 469-477. (Pubitemid 43667997)
2. Manolis A, Doumas M: Sexual dysfunction: the 'prima ballerina' of hypertension-related quality-of-life complications. J Hypertens 2008; 26: 2074-2084.
3. Manolis A, Doumas M: Antihypertensive treatment and sexual dysfunction. Curr Hypertens Rep 2012; 14: 285-292.
4. Doumas M, Douma S: Sexual dysfunction in essential hypertension: myth or reality? J Clin Hypertens 2006; 8: 269-274.
5. Vlachopoulos C, Ioakeimidis N, Terentes- Printzios D, Stefanadis C: The triad: erectile dysfunction, endothelial dysfunction, cardiovascular disease. Curr Pharm Des 2008; 14: 3700-3714.
6. Doumas M, Douma S: The effect of antihypertensive drugs on erectile function: a proposed management algorithm. J Clin Hypertens 2006; 8: 359-364.
7. Viigimaa M, Doumas M, Vlachopoulos C, et al European Society of Hypertension Working Group on Sexual Dysfunction. Hypertension and sexual dysfunction: time to act. J Hypertens 2011; 29: 403-407.
8. Yang L, Yu J, Ma R, et al: The effect of combined antihypertensive treatment (felodipine with either irbesartan or metoprolol) on erectile function: a randomized controlled trial. Cardiology 2013;125:235-241.
9. Dusing R: Effect of the angiotensin II antagonist valsartan on sexual function in hypertensive men. Blood Press 2003; 12:S29-S34.
10. Llisterri JL, Lozano Vidal JV, Aznar Vicente J, et al: Sexual dysfunction in hypertensive patients treated with losartan. Am J Med Sci 2001; 321: 336-341. (Pubitemid 32428834)
11. Fogari R, Zoppi A, Poletti L, et al: Sexual activity in hypertensive men treated with valsartan or carvedilol: a crossover study. Am J Hypertens 2001; 14: 27-31. (Pubitemid 32105914)
12. Fogari R, Preti P, Derosa G, et al: Effect of antihypertensive treatment with valsartan or atenolol on sexual activity and plasma testosterone in hypertensive men. Eur J Clin Pharmacol 2001; 58: 177-180.
13. Douma S, Doumas M, Petidis K, Triantafyllou A, Zamboulis C: Beta blockers and sexual dysfunction: bad guys - good guys; in Endo M, Matsumoto N: Beta Blockers: New Research. New York, Nova Science, 2008, pp 1-13.
14. Silvestri A, Galetta P, Cerquetani E, et al: Report of erectile dysfunction after therapy with beta-blockers is related to patient knowledge of side effects and is reversed by placebo. Eur Heart J 2003; 24: 1928-1932. (Pubitemid 37322702)
15. Cocco G: Erectile dysfunction after therapy with metoprolol: the Hawthorne effect. Cardiology 2009; 112: 174-177.
16. Böhm M, Baumhäkel M, Teo K, et al, ONTARGET/TRANSCEND Erectile Dysfunction Substudy Investigators: Erectile dysfunction predicts cardiovascular events in highrisk patients receiving telmisartan, ramipril, or both. Circulation 2010; 121: 1439-1446.
17. Grimm RH, Grandits GA, Prineas RJ, Mc-Donald RH, Lewis CE, Flack JM, et al: Longterm effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women: Treatment of Mild Hypertension Study (TOMHS). Hypertension 1997; 29: 8-14. (Pubitemid 27078334)
18. Ma R, Yu J, Xu D, et al: Effect of felodipine with irbesartan or metoprolol on sexual function and oxidative stress in women with essential hypertension. J Hypertens 2011; 30: 210-216.
19. Deveci S, O'Brien K, Ahmed A, Parker M, Guhring P, Mulhall JP: Can the International Index of Erectile Function distinguish between organic and psychogenic erectile function? BJU Int 2008; 102: 354-356. (Pubitemid 352019193)