Ion-pair strategy for enabling amifostine oral absorption: Rat in situ and in vivo experiments

European Journal of Pharmaceutical Sciences

Volumn 49, Issue 4, 2013, Pages 499-504

  Samiei, N ^a,b   Mangas Sanjuan, V ^a   Gonzalez Alvarez I ^a   Foroutan, M ^b   Shafaati, A ^b   Zarghi, A ^b   Bermejo, M ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Amifostine; In situ intestinal perfusion; In vivo bioavailability; Intestinal absorption; Ion pair; Permeability

Indexed keywords

2 (3 AMINOPROPYLAMINO)ETHANETHIOL; ALKALINE PHOSPHATASE; AMIFOSTINE; BENZOIC ACID; COUNTERION; METOPROLOL; PHTHALIC ACID; SUCCINIC ACID;

ANIMAL EXPERIMENT; ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG HALF LIFE; IN VIVO STUDY; INTESTINE ABSORPTION; INTESTINE PERFUSION; LIPOPHILICITY; MALE; NONHUMAN; PH; PRIORITY JOURNAL; RAT; WATER ABSORPTION;

EID: 84879465475     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.04.025     Document Type: Article

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