Contemporary biological markers of exposure to fluoride

Monographs in Oral Science

Volumn 22, Issue , 2011, Pages 37-51

  Rugg Gunn, Andrew John ^a   Villa, Alberto Enrique ^b   Buzalaf, Marília Rabelo Afonso ^c  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICARIES AGENT; BIOLOGICAL MARKER; FLUORIDE;

ARTICLE; BLOOD; BODY BURDEN; BODY FLUID; BONE; CHEMISTRY; HUMAN; URINE;

BIOLOGICAL MARKERS; BODY BURDEN; BODY FLUIDS; BONE AND BONES; CARIOSTATIC AGENTS; FLUORIDES; HUMANS;

EID: 84879429305     PISSN: 00770892     EISSN: 16623843     Source Type: Book Series    
DOI: 10.1159/000325137     Document Type: Article

References (76)

1. WHO: Fluorides and oral health. Technical Report Series 846. Geneva, WHO, 1994.
2. Selwitz RH: Introduction to the workshop on methods for assessing fluoride accumulation and effects in the body. Adv Dent Res 1994;8:3-4.
3. Medical Research Council: Water fluoridation and health (working group report). London, Medical Research Council, 2002.
4. Trull AK, Demers LM, Holt DW, Johnston A, Tredger JM, Price CP: Biomarkers of Disease: An Evidence-Based Approach. Cambridge, Cambridge University Press, 2002.
5. Risteli J, Kauppila S, Jukkola A, Marjoniemi E, Melkko J, Risteli L: Biomarkers of bone formation; in Trull AK, Demers LM, Holt DW, Johnston A, Tredger JM, Price CP (eds): Biomarkers of Disease: An Evidence-Based Approach. Cambridge, Cambridge University Press, 2002, pp 115-121.
6. Eastell R, Hart S: Bone turnover markers in clinical practice; in Trull AK, Demers LM, Holt DW, Johnston A, Tredger JM, Price CP (eds): Biomarkers of Disease: An Evidence-Based Approach. Cambridge, Cambridge University Press, 2002, pp 99-114.
7. Robins SP: Biochemical markers of bone resorption; in Trull AK, Demers LM, Holt DW, Johnston A, Tredger JM, Price CP (eds): Biomarkers of Disease: An Evidence-Based Approach. Cambridge, Cambridge University Press, 2002, pp 122-132.
8. Jones R: Using intelligent systems in clinical decision support; in Trull AK, Demers LM, Holt DW, Johnston A, Tredger JM, Price CP (eds): Biomarkers of Disease: An Evidence-Based Approach. Cambridge, Cambridge University Press, 2002, pp 32-44.
9. Marshall WJ, Bangert SK: Clinical Chemistry, ed 6. Edinburgh, Mosby, 2008, pp 1-13.
10. Armstrong WD, Gedalia I, Singer L, Weatherell JA, Weidmann SM: Distribution of fluorides; in WHO (ed): Fluorides and Human Health. Geneva, WHO, 1970, pp 93-139.
11. Murray JJ, Rugg-Gunn AJ, Jenkins GN: Fluorides in caries prevention, ed 3. Oxford, Butterworth-Heinemann, 1991, pp 262-294.
12. McClure FJ, Mitchell HH, Hamilton TS, Kinser CA: Balances of fluorine ingested from various sources in food and water by five young men. J Ind Hyg Toxicol 1945;27:159-170.
13. Whitford GM: The Metabolism and Toxicology of Fluoride, ed 2. Basel, Karger, 1996.
14. Ekstrand J, Alvan G, Boreus LO, Norlin A: Pharmacokinetics of fluoride in man after single and multiple oral doses. Europ J Clin Pharmacol 1977;12: 311-317. (Pubitemid 8222320)
15. Ekstrand J: Relationship between fluoride in the drinking water and the plasma fluoride concentration in man. Caries Res 1978;12:123-127. (Pubitemid 8298796)
16. Ekstrand J, Boreus LO, de Chateau P: No evidence of transfer of fluoride from plasma to breast milk. BMJ 1981;283: 761-762. (Pubitemid 11050959)
17. Oliveby A, Lagerlof F, Ekstrand J, Dawes C: Influence of flow rate, pH and plasma fluoride concentrations on fluoride concentration in human parotid saliva. Arch Oral Biol 1989;34:191-194.
18. Oliveby A, Lagerlof F, Ekstrand J, Dawes C: Studies on fluoride concentrations in human submandibular/sublingual saliva and their relation to flow rate and plasma fluoride levels. J Dent Res 1989; 68:146-149.
19. Oliveby A, Lagerlof F, Ekstrand J, Dawes C: Studies on fluoride excretion in human whole saliva and its relation to flow rate and plasma fluoride levels. Caries Res 1989;23:243-246. (Pubitemid 19169755)
20. Whitford GM, Thomas JE, Adair SM: Fluoride in whole saliva, parotid ductal saliva and plasma in children. Arch Oral Biol 1999;44:785-788. (Pubitemid 29448979)
21. Levy FM, Bastos JR, Buzalaf MA: Nails as biomarkers of fluoride in children of fluoridated communities. J Dent Child 2004;71:121-125. (Pubitemid 39611953)
22. Maguire A, Zohouri FV, Mathers JC, Steen IN, Hindmarsh PN, Moynihan PJ: Bioavailability of fluoride in drinking water: a human experiment. J Dent Res 2005;84:989-993. (Pubitemid 43828143)
23. Cardoso VE, Whitford GM, Buzalaf MA: Relationship between daily fluoride intake from diet and the use of dentrifice and human plasma fluoride concentrations. Arch Oral Biol 2006;51:552-557. (Pubitemid 43849633)
24. Whitford GM, Sampaio FC, Pinto CS, Maria AG, Cardoso VES, Buzalaf MAR: Pharmacokinetics of ingested fluoride: lack of effect of chemical compound. Arch Oral Biol 2008;53:1037-1041.
25. Cardoso VES, Whitford GM, Aoyama H, Buzalaf MAR: Daily variations in human plasma fluoride concentrations. J Fluorine Chem 2008;129:1193-1198.
26. Buzalaf MAR, Leite AL, Carvalho NTA, Rodrigues MHC, Takamori ER, Nicolielo DB, Levy FM, Cardoso VES: Bioavailability of fluoride administered as sodium fluoride or monofluorophosphate to humans. J Fluoride Chem 2008;129:691-694.
27. Carvalho JG, Leite AL, Yan D, Everett ET, Whitford GM, Buzalaf MAR: Influence of genetic background on fluoride metabolism in mice. J Dent Res 2009;88:1054-1058.
28. Ekstrand J, Zeigler EE, Nelson SE, Fomon SJ: Absorption and retention of dietary and supplemental fluoride by infants. Adv Dent Res 1994;8:175-180.
29. Spencer H, Lewin I, Wistrowski E, Samachson J: Fluoride metabolism in man. Am J Med 1970;49:807-813.
30. Rao HV, Beliles RP, Whitford GM, Turner CH: A physiologically based pharmacokinetic model for fluoride uptake by bone. Reg Toxicol Pharmacol 1995;22:30-42.
31. Narita N, Kato K, Nakagaki H, Ohno N, Kameyama Y, Weatherell JA: Distribution of fluorides concentration in rats bone. Calcif Tiss Int 1990;46:200-204. (Pubitemid 20084077)
32. Li J, Nakagaki H, Kato K, Ishiguro K, Ohno N, Kameyama Y, Mukai M, Ikeda M, Weatherell J, Robinson C: Distribution profiles of fluoride in three different kinds of rats bone. Bone 1993;14: 835-842.
33. Buzalaf MAR, Caroselli EE, Carvalho JG, Oliveira RC, Cardoso VES, Whitford GM: Bone surface and whole bone as biomarkers of acute fluoride exposure. J Analyt Toxicol 2005;29:810-813. (Pubitemid 41803382)
34. Ishiguro K, Nakagaki H, Tsuboi S, Narita N, Kato K, Li J, Kamei H, Yoshioka I, Miyauchi K, Hosoe H, et al: Distribution of fluoride in cortical bone of human rib. Calcif Tiss Int 1993;52:278-282. (Pubitemid 23097159)
35. Bezerra de Menezes LM, Volpato MC, Rosalen PL, Cury JA: Bone as a biomarker of acute fluoride toxicity. Forensic Sci Int 2003;137:209-214. (Pubitemid 37373633)
36. Buzalaf MAR, Caroselli EE, Oliveira RC, Granjeiro JM, Whitford GM: Nail and bone surface as biomarkers of acute fluoride exposure in rats. J Analyt Toxicol 2004;28:249-252. (Pubitemid 38581578)
37. Charen J, Taves DR, Stamm JW, Parkins FM: Bone fluoride concentration associated with fluoridated drinking water. Calcif Tissue Int 1979;27:95-99. (Pubitemid 10220021)
38. Weidmann SM, Weatherell JA: Distribution in hard tissues; in WHO (ed): Fluorides and Human Health. Geneva, WHO, 1970, pp 104-128.
39. Parkins FM, Tinanoff N, Moutinho M, Anstey MB: Relationships of human plasma fluoride and bone fluoride to age. Calcif Tiss Res 1974;16:335-338.
40. Richards A, Mosekilde L, Sogaard CH: Normal age-related changes in fluoride content of vertebral trabecular bone -relation to bone quality. Bone 1994; 15:21-26. (Pubitemid 24107937)
41. Everett ET, McHenry MA, Reynolds N, Eggertsson H, Sullivan J, Kantmann C, Martinez-Mier EA, Warrick JM, Stookey GK: Dental fluorosis: variability among different inbred mouse strains. J Dent Res 2002;81:794-798.
42. Zipkin I, McClure FJ, Leone NC, Lee WA: Fluoride deposition in human bones after prolonged ingestion of fluoride in drinking water. Publ Health Rep 1958;73:732-740.
43. Brunn C, Givskov H, Thylstrup A: Whole saliva fluoride after toothbrushing with NaF and MFP dentrifices with different F concentrations. Caries Res 1984;18: 282-288. (Pubitemid 14140807)
44. Schamschula RG, Sugar E, Un PSH, Toth K, Barmes DE, Adkins BL: Physiological indicators of fluoride exposure and utilization: an epidemiological study. Community Dent Oral Epidemiol 1985;13: 104-107.
45. Boros I, Keszler P, Banoczy J: Fluoride concentrations of unstimulated whole and labial gland saliva in young adults after fluoride intake with milk. Caries Res 2001;35:167-172. (Pubitemid 33639888)
46. Petersson LG, Arvidsson I, Lynch E, Engstrom K, Twetman S: Fluoride concentrations in saliva and dental plaque in young children after intake of fluoridated milk. Caries Res 2002;36:40-43.
47. Hedman J, Sjoman R, Sjostrom I, Twetman S: Fluoride concentration in saliva after consumption of a dinner meal prepared with fluoridated salt. Caries Res 2006;40:158-162. (Pubitemid 43325876)
48. Pessan JP, Silva SM, Lauris JR, Sampaio FC, Whitford GM, Buzalaf MA: Fluoride uptake by plaque from water and from dentifrice. J Dent Res 2008;87: 461-465.
49. Yao K, Gron P: Fluoride concentrations in duct saliva and in whole saliva. Caries Res 1970;4:321-331.
50. Twetman S, Nederfors, Petersson LG: Fluoride concentration in whole saliva and separate gland secretions in schoolchildren after intake of fluoridated milk. Caries Res 1998;32:412-416. (Pubitemid 128526874)
51. Ekstrand J: Fluoride concentrations in saliva after single oral doses and their relation to plasma fluoride. Scand J Dent Res 1977;85:16-17. (Pubitemid 8019515)
52. Shannon IL, Suddick RP, Edmonds EJ: Effect of rate of gland function on parotid saliva fluoride concentration in the human. Caries Res 1973;7:1-10.
53. Crosby ND, Shepherd PA: Studies on patterns of fluid intake, water balance and fluoride. Med J Aust 1957;ii: 341-346.
54. Hodge HC, Smith FA, Gedalia I: Excretion of fluorides; in WHO (ed): Fluorides and human health. Geneva, WHO, 1970, pp 141-161.
55. Backer Dirks O, Jongeling-Eijndhoven JMPA, Flissebaalje TD, Gedalia I: Total and free ionic fluoride in human and cows milk as determined by gas-liquid chromatography and the fluoride electrode. Caries Res 1974;8:181-186.
56. Koparal E, Ertugrul F, Oztekin K: Fluoride levels in breast milk and infant foods. J Clin Pediatr Dent 2000;24: 299-302.
57. Ericsson Y, Gydell K, Hammarskioeld T: Blood plasma fluoride: an indicator of skeletal fluoride content. J Int Res Commun Syst 1973;1:33-35.
58. Waterhouse C, Taves D, Munzer A: Serum inorganic fluoride: changes related to previous fluoride intake, renal function and bone resorption. Clin Sci 1980;58:145-152. (Pubitemid 10021928)
59. EPA: Fluoride in drinking water; a scientific review of EPAs standards (2006). Committee on Fluoride in Drinking Water. Board on Environmental Studies and Toxicology. Division on Earth and Life Studies. National Research Council of the National Academies. Washington, National Academies Press Washington, 2006.
60. Czarnowski W, Krechniak J: Fluoride in the urine, hair, and nails of phosphate fertiliser workers. Br J Ind Med 1990;47:349-351. (Pubitemid 20170619)
61. Czarnowski W, Krechniak J, Urbanska B, Stolarska K, Taraszewska- Czarnowska M, Muraszko-Klaudel A: The impact of water-borne fluoride on bone density. Fluoride 1999;32:91-95. (Pubitemid 29394840)
62. Villa AE, Anabalón M, Cabezas L: The fractional urinary fluoride excretion in young children under stable fluoride intake conditions. Community Dent Oral Epidemiol 2000;28:344-355.
63. Haftenberger M, Viergutz G, Neumeister V, Hetzer G: Total fluoride intake and urinary excretion in German children aged 3-6 years. Caries Res 2001;35: 451-457. (Pubitemid 33636865)
64. Villa AE, Cabezas L, Anabalón M, Garza E: The fractional urinary fluoride excretion of adolescents and adults under customary fluoride intake conditions, in a community with 0.6 mg F/L in its drinking water. Community Dent Health 2004;21:11-18. (Pubitemid 38918268)
65. Maguire A, Zohouri FV, Hindmarch PN, Hatts J, Moynihan PJ: Fluoride intake and urinary excretion in 6-to 7-year-old children living in optimally, suboptimally and non-fluoridated areas. Community Dent Oral Epidemiol 2007; 35:479-488.
66. Villa A, Anabalon M, Zohouri V, Maguire A, Franco AM, Rugg-Gunn A: Relationships between fluoride intake, urinary fluoride excretion and fluoride retention in children and adults: an analysis of available data. Caries Res 2010;44:60-68.
67. Villa AE, Anabalón M, Rugg-Gunn A: Fractional urinary fluoride excretion of young female adults during the diurnal and nocturnal periods. Caries Res 2008; 42:275-281.
68. Whitford GM, Pashley DH, Stringer GI: Fluoride renal clearance: a pHdependent event. Am J Physiol 1976;230: 527-532.
69. Schiffl HH, Binswanger U: Human urinary fluoride excretion as influenced by renal functional impairment. Nephron 1980;26:69-72. (Pubitemid 10093178)
70. Hanhijärvi H, Penttilä I: The relationship between human ionic plasma fluoride and serum creatinine concentrations in cases of renal and cardiac insufficiency in a fluoridated community. Proc Finn Dent Soc 1981;77: 330-335.
71. Ekstrand J, Hardell LI, Spak CJ: Fluoride balance studies on infants in a 1 ppm water fluoride area. Caries Res 1984;18:87-92. (Pubitemid 14220630)
72. Maheshwari UR, McDonald JT, Schneider VS, Brunetti AJ, Leybin L, Newbrun E, Hodge HC: Fluoride balance studies in ambulatory healthy men with and without fluoride supplements. Am J Clin Nutr 1981;34:2679-2684. (Pubitemid 12223910)
73. Zohouri FV, Rugg-Gunn AJ: Total fluoride intake and urinary excretion in 4-year-old Iranian children residing in low-fluoride areas. Br J Nutr 2000;83: 15-25. (Pubitemid 30052861)
74. Franco AM, Saldarriaga A, Martignon S, González MC, Villa AE: Fluoride intake and fractional urinary fluoride excretion of Colombian preschool children. Community Dent Health 2005;22:272-278. (Pubitemid 41796808)
75. Marthaler TM: Monitoring of renal fluoride excretion in community preventive programmes on oral health. Geneva, World Health Organization, 1999.
76. Whitford G: Fluoride metabolism and excretion in children. J Public Health Dent 1999;59:224-228.