Obesity and susceptibility to severe outcomes following respiratory viral infection

Thorax

Volumn 68, Issue 7, 2013, Pages 684-686

  Almond, Mark H ^a,b   Edwards, Michael R ^a   Barclay, Wendy S ^b   Johnston, Sebastian L ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; ALPHA INTERFERON; BETA INTERFERON; INTERFERON; LEPTIN; MESSENGER RNA;

2009 H1N1 INFLUENZA; ADAPTIVE IMMUNITY; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPLEX FORMATION; CYTOKINE RELEASE; CYTOKINE RESPONSE; DISEASE SEVERITY; ENDOCYTOSIS; HUMAN; IMMUNOMODULATION; INFLUENZA A; INNATE IMMUNITY; NONHUMAN; OBESITY; OUTCOME ASSESSMENT; PANDEMIC INFLUENZA; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; VIRAL RESPIRATORY TRACT INFECTION;

IMMUNODEFICIENCY; INNATE IMMUNITY; RESPIRATORY INFECTION; VIRAL INFECTION;

COMMUNITY-ACQUIRED INFECTIONS; DISEASE OUTBREAKS; HUMANS; MORBIDITY; OBESITY; RESPIRATORY TRACT INFECTIONS; RISK FACTORS; VIRUS DISEASES; WORLD HEALTH;

EID: 84879417961     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2012-203009     Document Type: Article

References (5)

1. Wang YC, McPherson K, Marsh T, et al. Health and economic burden of the projected obesity trends in the USA and the UK. Lancet 2011;378:815-25.
2. Corne JM, Marshall C, Smith S, et al. Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study. Lancet 2002;359:831-4. (Pubitemid 34233753)
3. Forbes RL, Gibson PG, Murphy VE, et al. Impaired type I and III interferon response to rhinovirus infection during pregnancy and asthma. Thorax 2012;67:209-14.
4. Smith AG, Sheridan PA, Harp JB, et al. Diet-induced obese mice have increased mortality and altered immune responses when infected with influenza virus. J Nutr 2007;137:1236-43. (Pubitemid 46701917)
5. Teran-Cabanillas E, Montalvo-Corral M, Caire-Juvera G, et al. Decreased interferon-α and interferon-β production in obesity and expression of suppressor of cytokine signaling. Nutrition 2013;29:207-12.