Nitric oxide may inhibit neointimal hyperplasia by decreasing isopeptidase T levels and activity in the vasculature

Journal of Vascular Surgery

Volumn 58, Issue 1, 2013, Pages 179-186

  Tsihlis, Nick D ^a   Kapadia, Muneera R ^a   Vavra, Ashley K ^a   Flannery, Walker D ^a   Oustwani, Christopher S ^a   Jiang, Qun ^a   Kibbe, Melina R ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; DITHIOTHREITOL; GLUTATHIONE; ISOPEPTIDASE T; NITRIC OXIDE; PROTEASOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; CAROTID ARTERY INJURY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NITROSYLATION; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; UBIQUITINATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; CAROTID ARTERY INJURIES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DITHIOTHREITOL; DOWN-REGULATION; ENDOPEPTIDASES; GLUTATHIONE; HUMANS; HYPERPLASIA; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NEOINTIMA; NITRIC OXIDE; NITRIC OXIDE DONORS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; S-NITROSO-N-ACETYLPENICILLAMINE; TIME FACTORS; UBIQUITINATION; VASCULAR SYSTEM INJURIES;

EID: 84879415817     PISSN: 07415214     EISSN: 10976809     Source Type: Journal    
DOI: 10.1016/j.jvs.2012.10.066     Document Type: Article

References (29)

1. L.L. Shears, M.R. Kibbe, A.D. Murdock, T.R. Billiar, A. Lizonova, and I. Kovesdi Efficient inhibition of intimal hyperplasia by adenovirus-mediated inducible nitric oxide synthase gene transfer to rats and pigs in vivo J Am Coll Surg 187 1998 295 306 (Pubitemid 28433437)
2. C.G. Pearce, S.F. Najjar, M.R. Kapadia, J. Murar, J. Eng, and B. Lyle Beneficial effect of a short-acting NO donor for the prevention of neointimal hyperplasia Free Radic Biol Med 44 2008 73 81 (Pubitemid 350138632)
3. M.R. Kapadia, L.W. Chow, N.D. Tsihlis, S.S. Ahanchi, J.W. Eng, and J. Murar Nitric oxide and nanotechnology: a novel approach to inhibit neointimal hyperplasia J Vasc Surg 47 2008 173 182
4. M.R. Kapadia, J.W. Eng, Q. Jiang, D.A. Stoyanovsky, and M.R. Kibbe Nitric oxide regulates the 26S proteasome in vascular smooth muscle cells Nitric Oxide 20 2009 279 288
5. A.Y. Amerik, S. Swaminathan, B.A. Krantz, K.D. Wilkinson, and M. Hochstrasser In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome EMBO J 16 1997 4826 4838 (Pubitemid 27348392)
6. K.D. Wilkinson, V.L. Tashayev, L.B. O'Connor, C.N. Larsen, E. Kasperek, and C.M. Pickart Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T Biochemistry 34 1995 14535 14546
7. T. Hadari, J.V. Warms, I.A. Rose, and A. Hershko A ubiquitin C-terminal isopeptidase that acts on polyubiquitin chains: role in protein degradation J Biol Chem 267 1992 719 727
8. S. Dayal, A. Sparks, J. Jacob, N. Allende-Vega, D.P. Lane, and M.K. Saville Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53 J Biol Chem 284 2009 5030 5041
9. T. Lacombe, and J.M. Gabriel Further characterization of the putative human isopeptidase T catalytic site FEBS Lett 531 2002 469 474 (Pubitemid 35336071)
10. C.M. Crews Feeding the machine: mechanisms of proteasome-catalyzed degradation of ubiquitinated proteins Curr Opin Chem Biol 7 2003 534 539 (Pubitemid 37315787)
11. L. Gregori, M.S. Poosch, G. Cousins, and V. Chau A uniform isopeptide-linked multiubiquitin chain is sufficient to target substrate for degradation in ubiquitin-mediated proteolysis J Biol Chem 265 1990 8354 8357
12. W. Li, and Y. Ye Polyubiquitin chains: functions, structures, and mechanisms Cell Mol Life Sci 65 2008 2397 2406
13. C.M. Pickart, and D. Fushman Polyubiquitin chains: polymeric protein signals Curr Opin Chem Biol 8 2004 610 616 (Pubitemid 39535722)
14. V. Chau, J.W. Tobias, A. Bachmair, D. Marriott, D.J. Ecker, and D.K. Gonda A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein Science 243 1989 1576 1583 (Pubitemid 19090506)
15. D. Finley, S. Sadis, B.P. Monia, P. Boucher, D.J. Ecker, and S.T. Crooke Inhibition of proteolysis and cell cycle progression in a multiubiquitination- deficient yeast mutant Mol Cell Biol 14 1994 5501 5509 (Pubitemid 24235979)
16. S. Raasi, R. Varadan, D. Fushman, and C.M. Pickart Diverse polyubiquitin interaction properties of ubiquitin-associated domains Nat Struct Mol Biol 12 2005 708 714 (Pubitemid 43086277)
17. M.R. Kibbe, J. Li, S. Nie, S.C. Watkins, A. Lizonova, and I. Kovesdi Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate J Vasc Surg 31 2000 1214 1228 (Pubitemid 30418493)
18. S.M. Yu, L.M. Hung, and C.C. Lin cGMP-elevating agents suppress proliferation of vascular smooth muscle cells by inhibiting the activation of epidermal growth factor signaling pathway Circulation 95 1997 1269 1277
19. N.D. Tsihlis, M.R. Kapadia, A.K. Vavra, Q. Jiang, B. Fu, and J. Martinez Nitric oxide decreases activity and levels of the 11S proteasome activator PA28 in the vasculature Nitric Oxide 27 2012 50 58
20. K.M. Timms, M.A. Ansari-Lari, W. Morris, S.N. Brown, and R.A. Gibbs The genomic organization of isopeptidase T-3 (ISOT-3), a new member of the ubiquitin specific protease family UBP Gene 217 1998 101 106 (Pubitemid 28427312)
21. M.A. Ansari-Lari, D.M. Muzny, J. Lu, F. Lu, C.E. Lilley, and S. Spanos A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13 Genome Res 6 1996 314 326 (Pubitemid 26161693)
22. S. Kostin, L. Pool, A. Elsasser, S. Hein, H.C. Drexler, and E. Arnon Myocytes die by multiple mechanisms in failing human hearts Circ Res 92 2003 715 724 (Pubitemid 36457635)
23. J. Herrmann, A.M. Saguner, D. Versari, T.E. Peterson, A. Chade, and M. Olson Chronic proteasome inhibition contributes to coronary atherosclerosis Circ Res 101 2007 865 874 (Pubitemid 350287173)
24. S. Meiners, M. Laule, W. Rother, C. Guenther, I. Prauka, and P. Muschick Ubiquitin-proteasome pathway as a new target for the prevention of restenosis Circulation 105 2002 483 489 (Pubitemid 34141706)
25. P.L. Faries, D.I. Rohan, M.C. Wyers, M.L. Marin, L.H. Hollier, and W.C. Quist Relationship of the 20S proteasome and the proteasome activator PA28 to atherosclerosis and intimal hyperplasia in the human vascular system Ann Vasc Surg 15 2001 628 633 (Pubitemid 33115646)
26. D.H. Stone, N. Sivamurthy, M.A. Contreras, L. Fitzgerald, F.W. LoGerfo, and W.C. Quist Altered ubiquitin/proteasome expression in anastomotic intimal hyperplasia J Vasc Surg 34 2001 1016 1022 (Pubitemid 33660660)
27. B. Lima, M.T. Forrester, D.T. Hess, and J.S. Stamler S-Nitrosylation in cardiovascular signaling Circ Res 106 2010 633 646
28. S.S. Ahanchi, V.N. Varu, N.D. Tsihlis, J. Martinez, C.G. Pearce, and M.R. Kapadia Heightened efficacy of nitric oxide-based therapies in type II diabetes mellitus and metabolic syndrome Am J Physiol Heart Circ Physiol 295 2008 H2388 H2398
29. M.R. Kibbe, J. Li, S. Nie, B.M. Choi, I. Kovesdi, and A. Lizonova Potentiation of nitric oxide-induced apoptosis in p53-/- vascular smooth muscle cells Am J Physiol Cell Physiol 282 2002 C625 C634