Lame broiler chickens respond to non-steroidal anti-inflammatory drugs with objective changes in gait function: A controlled clinical trial

Veterinary Journal

Volumn 196, Issue 3, 2013, Pages 477-482

  Caplen, G ^a   Colborne, G R ^a   Hothersall, B ^a   Nicol, C J ^a   Waterman Pearson, A E ^a   Weeks, C A ^a   Murrell, J C ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Broiler; Gait; Kinematics; Lameness; NSAID

Indexed keywords

CARPROFEN; MELOXICAM; PLACEBO;

ANIMAL LAMENESS; ARTICLE; BODY MASS; BROILER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; FEMALE; GAIT; KINEMATICS; MALE; NONHUMAN; WALKING DIFFICULTY; WALKING SPEED;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARBAZOLES; CHICKENS; GAIT; LAMENESS, ANIMAL; POULTRY DISEASES; THIAZINES; THIAZOLES;

GALLUS GALLUS;

EID: 84879412557     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2012.12.007     Document Type: Article

References (22)

1. Abourachid A. Kinematic parameters of terrestrial locomotion in cursorial (ratites), swimming (ducks), and striding birds (quail and guinea fowl). Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology 2001, 131:113-119.
2. Baert K., De Backer P. Comparative pharmacokinetics of three non-steroidal anti-inflammatory drugs in five bird species. Comparative Biochemistry and Physiology - Part C 2003, 134:25-33.
3. Bradshaw R.H., Kirkden R.D., Broom D.M. A review of the aetiology and pathology of leg weakness in broilers in relation to welfare. Poultry and Avian Biology Reviews 2002, 13:45-103.
4. Buchner H.H., Obermüller S., Scheidl M. Body centre of mass movement in the lame horse. Equine Veterinary Journal Suppl. 2001, 33:122-127.
5. Caplen G., Hothersall B., Murrell J.C., Nicol C.J., Waterman-Pearson A.E., Weeks C.A., Colborne G.R. Kinematic analysis quantifies gait abnormalities associated with lameness in broiler chickens and identifies evolutionary gait differences. PLoS ONE 2012, 7:e40800.
6. Caplen, G., Hothersall, B., Sandilands, V., McKeegan, D., Baker, L., Murrell, J.C., Waterman-Pearson, A.E., 2011. Thermal nociception as a tool to investigate NSAID analgesia in a model of inflammatory pain in broilers. In: Proceedings of the 5th International Conference on the Assessment of Animal Welfare at Farm and Group Level, August 8-11, 2011, University of Guelph, Canada, pp. 74.
7. Colborne G.R., Walker A.M., Tattersall A.J., Fuller C.J. Effect of trotting velocity on work patterns of the hind limbs of Greyhounds. American Journal of Veterinary Research 2006, 67:1293-1298.
8. Corr S.A., McCorquodale C.C., Gentle M.J. Gait analysis of poultry. Research in Veterinary Science 1998, 6:233-238.
9. Corr S.A., Gentle M.J., McCorquodale C.C., Bennett D. The effect of morphology on walking ability in the modem broiler: A gait analysis study. Animal Welfare 2003, 12:159-171.
10. Danbury T.C., Weeks C.A., Waterman-Pearson A.E., Kestin S.C., Chambers J.P. Self-selection of the analgesic drug carprofen by lame broiler chickens. Veterinary Record 2000, 146:307-311.
11. Farage-Elwar M. Enzyme and behavioural changes in young chicks as a result of carbaryl treatment. Journal of Toxicology and Environmental Health 1989, 26:119-131.
12. Hocking P.M., Robertson G.W., Gentle M.J. Effects of anti-inflammatory steroid drugs on pain coping behaviours in a model of articular pain in domestic fowl. Research in Veterinary Science 2001, 69:161-166.
13. Hocking P.M., Robertson G.W., Gentle M.J. Effects of non-steroidal anti-inflammatory drugs on pain-related behaviour in a model of articular pain in the domestic fowl. Research in Veterinary Science 2005, 78:69-75.
14. Hothersall, B., Caplen, G., Nolan, A., Monteiro, A., Waterman-Pearson, A.E., Nicol, C., Weeks, C., Sear, J., Murrell, J., 2012. Pharmacokinetics of carprofen in broiler chickens. In: Proceedings of the Association of Veterinary Anaesthetists Spring Meeting, Davos, Switzerland, March 2012.
15. Hughes R.A. Strain-dependent morphine-induced analgesic and hyperalgesic effects on thermal nociception in domestic fowl (Gallus gallus). Behavioral Neuroscience 1990, 104:619-624.
16. Kestin S.C., Knowles T.G., Tinch A.E., Gregory N.G. Prevalence of leg weakness in broiler chickens and its relationship with genotype. Veterinary Record 1992, 131:190-194.
17. Knowles T.G., Kestin S.C., Haslam S.M., Brown S.N., Green L.E., Butterworth A., Pope S.J., Pfeiffer D., Nicol C.J. Leg disorders in broiler chickens: Prevalence, risk factors and prevention. PLoS ONE 2008, 3:E1545.
18. McGeown D., Danbury T.C., Waterman-Pearson A.E., Kestin S.C. Effect of carprofen on lameness in broiler chickens. Veterinary Record 1999, 144:668-671.
19. Reiter K., Bessei W. Gait analysis in laying hens and broilers with and without leg disorders. Equine Veterinary Journal Suppl. 1997, 23:110-112.
20. Roy W.E. Examination of the canine locomotor system. Veterinary Clinics of North America 1971, 1:53-70.
21. Siegel P.B., Gustin S.J., Katanbaf M.N. Motor ability and self-selection of an analgesic drug by fast-growing chickens. Journal of Applied Poultry Research 2011, 20:249-252.
22. Weeks C.A., Danbury T.D., Davies H.C., Hunt P., Kestin S.C. The behaviour of broiler chickens and its modification by lameness. Applied Animal Behaviour Science 2000, 67:111-125.