Impact of anesthetics on 3′-[18F]Fluoro-3′- deoxythymidine ([18F]FLT) uptake in animal models of cancer and inflammation

Molecular Imaging

Volumn 12, Issue 5, 2013, Pages

  Fuchs, Kerstin ^a   Kukuk, Damaris ^a   Mahling, Moritz ^a   Quintanilla Martinez, Leticia ^a   Reischl, Gerald ^a   Reutershan, Jörg ^a   Lang, Florian ^a   Röcken, Martin ^a   Pichler, Bernd J ^a   Kneilling, Manfred ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; MAMMALS; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY;

AIR BREATHING; ANIMAL MODELS OF CANCER; ISOFLURANE; MEDETOMIDINE; POSITRON EMISSION; REGIONS OF INTEREST; TIME-ACTIVITY CURVES; TOMOGRAPHIC;

ANESTHETICS;

2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; 3' FLUOROTHYMIDINE; ANESTHETIC AGENT; KI 67 ANTIGEN;

ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; DISEASE MODEL; FEMALE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; METABOLISM; MOUSE; NEOPLASM; PATHOLOGY; SCINTISCANNING;

ANESTHETICS; ANIMALS; DIDEOXYNUCLEOSIDES; DISEASE MODELS, ANIMAL; FEMALE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KI-67 ANTIGEN; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEOPLASMS;

EID: 84879402628     PISSN: 15353508     EISSN: None     Source Type: Journal    
DOI: 10.2310/7290.2012.00042     Document Type: Article

References (40)

1. Been LB, Suurmeijer AJ, Cobben DC, et al. [18F]FLT-PET in oncology: current status and opportunities. Eur J Nucl Med Mol Imaging 2004;31:1659-72, doi:10.1007/s00259-004-1687-6. (Pubitemid 40104613)
2. van Waarde A, Jager PL, Ishiwata K, et al. Comparison of sigma-ligands and metabolic PET tracers for differentiating tumor from inflammation. J Nucl Med 2006;47:150-4. (Pubitemid 46768524)
3. Shields AF, Grierson JR, Dohmen BM, et al. Imaging proliferation in vivo with [F-18]FLT and positron emission tomography. Nat Med 1998;4:1334-6, doi:10.1038/3337. (Pubitemid 28512118)
4. Eintrei C, Sokoloff L, Smith CB. Effects of diazepam and ketamine administered individually or in combination on regional rates of glucose utilization in rat brain. Br J Anaesth 1999;82:596-602, doi:10.1093/bja/82.4. 596. (Pubitemid 29151246)
5. Flores JE, McFarland LM, Vanderbilt A, et al. The effects of anesthetic agent and carrier gas on blood glucose and tissue uptake in mice undergoing dynamic FDG-PET imaging: sevoflurane and isoflurane compared in air and in oxygen. Mol Imaging Biol 2008; 10:192-200, doi:10.1007/s11307-008-0137-4.
6. Fueger BJ, Czernin J, Hildebrandt I, et al. Impact of animal handling on the results of 18F-FDG PET studies in mice. J Nucl Med 2006;47:999-1006. (Pubitemid 46939953)
7. Cullen BM, Walker HC. The effect of several different anaesthetics on the blood pressure and heart rate of the mouse and on the radiation response of the mouse sarcoma RIF-1. Int J Radiat Biol Relat Stud Phys Chem Med 1985;48:761-71, doi:10.1080/09553008514551861. (Pubitemid 16257050)
8. Zanelli GD, Lucas PB, Fowler JF. The effect of anaesthetics on blood perfusion in transplanted mouse tumours. Br J Cancer 1975; 32:380-90, doi:10.1038/bjc.1975.238.
9. Menke H, Vaupel P. Effect of injectable or inhalational anesthetics and of neuroleptic, neuroleptanalgesic, and sedative agents on tumor blood flow. Radiat Res 1988;114:64-76, doi:10.2307/3577144.
10. Fortis S, Spieth PM, Lu WY, et al. Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury. Intensive Care Med 2012;38:1548-55, doi:10.1007/s00134-012-2610-4.
11. Carroll GL, Hartsfield SM. General anesthetic techniques in ruminants. Vet Clin North Am Food Anim Pract 1996;12:627-61.
12. Sinclair MD. A review of the physiological effects of alpha2-agonists related to the clinical use of medetomidine in small animal practice. Can Vet J 2003;44:885-97. (Pubitemid 37527346)
13. Olkkola KT, Ahonen J. Midazolam and other benzodiazepines. Handb Exp Pharmacol 2008;182:335-60, doi:10.1007/978-3-540-74806-9-16.
14. Fuchs K, Kukuk D, Reischl G, et al. Oxygen breathing impacts 3'-deoxy-3'-(18)F-fluorothymidine (18F-FLT) uptake in mouse models of arthritis and cancer. J Nucl Med 2012;53:823-30, doi:10.2967/jnumed.111.101808.
15. Brattain MG, Strobel-Stevens J, Fine D, et al. Establishment of mouse colonic carcinoma cell lines with different metastatic properties. Cancer Res 1980;40:2142-6. (Pubitemid 10082214)
16. Judenhofer MS, Wehrl HF, Newport DF, et al. Simultaneous PET-MRI: a new approach for functional and morphological imaging. Nat Med 2008;14:459-65, doi:10.1038/nm1700. (Pubitemid 351499385)
17. Kouskoff V, Korganow AS, Duchatelle V, et al. Organ-specific disease provoked by systemic autoimmunity. Cell 1996;87:811-22, doi:10.1016/S0092- 8674(00)81989-3. (Pubitemid 26404281)
18. Monach PA, Mathis D, Benoist C. The K/BxN arthritis model. Curr Protoc Immunol 2008; Chapter 15:Unit 15.22. doi:10.1002/0471142735.im1522s81.
19. Kneilling M, Hultner L, Pichler BJ, et al. Targeted mast cell silencing protects against joint destruction and angiogenesis in experimental arthritis in mice. Arthritis Rheum 2007;56:1806-16, doi:10.1002/art.22602. (Pubitemid 47110380)
20. Reischl G, Wei R, Ehrlichmann W, et al. Simplified, automated synthesis of 3'-[18F]fluoro-3'-deoxy-thymidine ([18F]FLT) and simple method for metabolite analysis in plasma. Radiochim Acta 2006;94:447-51, doi:10.1524/ract.2006.94.8. 447.
21. Constantinescu CC, Mukherjee J. Performance evaluation of an Inveon PET preclinical scanner. Phys Med Biol 2009;54:2885-99, doi:10.1088/0031-9155/54/9/ 020.
22. Schwartz DD, Clark TP. Selectivity of atipamezole, yohimbine and tolazoline for alpha-2 adrenergic receptor subtypes: implications for clinical reversal of alpha-2 adrenergic receptor mediated sedation in sheep. J Vet Pharmacol Ther 1998;21:342-7, doi:10.1046/j.1365-2885.1998.00151.x. (Pubitemid 28488097)
23. Baudelet C, Gallez B. Effect of anesthesia on the signal intensity in tumors using BOLD-MRI: comparison with flow measurements by laser Doppler flowmetry and oxygen measurements by luminescence-based probes. Magn Reson Imaging 2004;22:905-12, doi:10.1016/j.mri.2004.02.005. (Pubitemid 38993519)
24. Clarke KW, Hall LW. "Xylazine" - a new sedative for horses and cattle. Vet Rec 1969;85:512-7, doi:10.1136/vr.85.19.512.
25. White PF, Way WL, Trevor AJ. Ketamine - its pharmacology and therapeutic uses. Anesthesiology 1982;56:119-36, doi:10.1097/00000542-198202000-00007. (Pubitemid 12164876)
26. Hikasa Y, Ohe N, Takase K, et al. Cardiopulmonary effects of sevoflurane in cats: comparison with isoflurane, halothane, and enflurane. Res Vet Sci 1997;63:205-10, doi:10.1016/S0034-5288 (97)90021-7. (Pubitemid 28045949)
27. Hitt BA, Mazze RI, Cousins MJ, et al. Metabolism of isoflurane in Fischer 344 rats and man. Anesthesiology 1974;40:62-7, doi: 10.1097/00000542-197401000- 00015.
28. Lee HT, Kim M, Kim N, et al. Isoflurane protects against renal ischemia and reperfusion injury and modulates leukocyte infiltration in mice. Am J Physiol Renal Physiol 2007;293:F713-22, doi: 10.1152/ajprenal.00161.2007. (Pubitemid 47403341)
29. Gurfinkel R, Czeiger D, Douvdevani A, et al. Ketamine improves survival in burn injury followed by sepsis in rats. Anesth Analg 2006;103:396-402, doi:10.1213/01.ane.0000226140.84281.3e. (Pubitemid 44140641)
30. Shaked G, Czeiger D, Dukhno O, et al. Ketamine improves survival and suppresses IL-6 and TNFalpha production in a model of Gram-negative bacterial sepsis in rats. Resuscitation 2004;62:237-42, doi:10.1016/j.resuscitation.2004. 02.015. (Pubitemid 39037266)
31. Boost KA, Flondor M, Hofstetter C, et al. The beta-adrenoceptor antagonist propranolol counteracts anti-inflammatory effects of isoflurane in rat endotoxemia. Acta Anaesthesiol Scand 2007;51: 900-8, doi:10.1111/j.1399- 6576.2007.01363.x. (Pubitemid 47063014)
32. Li QF, Zhu YS, Jiang H, et al. Isoflurane preconditioning ameliorates endotoxin-induced acute lung injury and mortality in rats. Anesth Analg 2009;109:1591-7, doi:10.1213/ANE.0b013e3181baf506.
33. Adams SD, Radhakrishnan RS, Helmer KS, et al. Effects of anesthesia on lipopolysaccharide-induced changes in serum cytokines. J Trauma 2008;65:170-4, doi:10.1097/TA.0b013e31805824ca.
34. Chiang N, Schwab JM, Fredman G, et al. Anesthetics impact the resolution of inflammation. PloS One 2008;3:e1879, doi:10.1371/journal.pone.0001879. (Pubitemid 351943827)
35. Amour J, Brzezinska AK, Weihrauch D, et al. Role of heat shock protein 90 and endothelial nitric oxide synthase during early anesthetic and ischemic preconditioning. Anesthesiology 2009;110: 317-25.
36. Goetzenich A, Roehl AB, Moza A, et al. The effects of metoprolol on hypoxia- and isoflurane-induced cardiac late-phase preconditioning. Acta Anaesthesiol Scand 2011;55:862-9, doi:10.1111/j.1399-6576.2011.02455.x.
37. de Klaver MJ, Buckingham MG, Rich GF. Isoflurane pretreatment has immediate and delayed protective effects against cytokine-induced injury in endothelial and vascular smooth muscle cells. Anesthesiology 2003;99:896-903, doi:10.1097/00000542-200310000-00023. (Pubitemid 37186081)
38. Toyama H, Ichise M, Liow JS, et al. Evaluation of anesthesia effects on [18F]FDG uptake in mouse brain and heart using small animal PET. Nucl Med Biol 2004;31:251-6, doi:10.1016/S0969-8051(03) 00124-0. (Pubitemid 38315120)
39. Lee KH, Ko BH, Paik JY, et al. Effects of anesthetic agents and fasting duration on 18F-FDG biodistribution and insulin levels in tumor-bearing mice. J Nucl Med 2005;46:1531-6.
40. Woo SK, Lee TS, Kim KM, et al. Anesthesia condition for (18)F-FDG imaging of lung metastasis tumors using small animal PET. Nucl Med Biol 2008;35:143-50, doi:10.1016/j.nucmedbio.2007.10.003. (Pubitemid 350298253)