Pyogenic arthritis, pyoderma gangrenosum, acne, and hidradenitis suppurativa (papash): A new autoinflammatory syndrome associated with a novel mutation of the pstpip1 gene

JAMA Dermatology

Volumn 149, Issue 6, 2013, Pages 762-764

  Marzano, Angelo V ^a   Trevisan, Valentina ^a   Gattorno, Marco ^b   Ceccherini, Isabella ^c   De Simone, Clara ^d   Crosti, Carlo ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b G GASLINI INSTITUTE   (Italy)

^c Istituto Giannina   (Italy)

^d CATHOLIC UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; DAPSONE; METHYLPREDNISOLONE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TACROLIMUS;

ABSCESS; ACNE; ADOLESCENT; ARTHRALGIA; BACTERIAL ARTHRITIS; CASE REPORT; FEMALE; GENE; GENE MUTATION; HOSPITAL ADMISSION; HUMAN; HUMAN TISSUE; JOINT RADIOGRAPHY; KELOID; LETTER; PAPASH SYNDROME; PHYSICAL EXAMINATION; POLYARTHRITIS; PRIORITY JOURNAL; PSTPIP1 GENE; PYODERMA GANGRENOSUM; SKIN BIOPSY; SKIN ULCER; SKINFOLD; SUPPURATIVE HIDRADENITIS;

ACNE VULGARIS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADOLESCENT; ARTHRITIS, INFECTIOUS; CYTOSKELETAL PROTEINS; FEMALE; HIDRADENITIS SUPPURATIVA; HUMANS; MUTATION; PYODERMA GANGRENOSUM; SYNDROME;

EID: 84879387220     PISSN: 21686068     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamadermatol.2013.2907     Document Type: Letter

References (3)

1. Braun-Falco M, Kovnerystyy O, Lohse P, Ruzicka T. Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH): a new autoinflammatory syndrome distinct from PAPA syndrome. J Am Acad Dermatol. 2012;66(3):409- 415.
2. Kastner DL, Aksentijevich I, Goldbach-Mansky R. Autoinflammatory disease reloaded: a clinical perspective. Cell. 2010;140(6):784-790.
3. Wise CA, Gillum JD, Seidman CE, et al. Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder. Hum Mol Genet. 2002;11(8):961-969. (Pubitemid 34449783)