Application of pharmacovigilance methods in occupational health surveillance: Comparison of seven disproportionality metrics

Safety and Health at Work

Volumn 3, Issue 2, 2012, Pages 92-100

  Bonneterre, Vincent ^a,b,c   Bicout, Dominique Joseph ^a   De Gaudemaris, Regis ^a,b,c  

^a LABORATOIRE TIMC IMAG   (France)

^b GRENOBLE UNIVERSITY HOSPITAL   (France)

^c French National Occupational Diseases Surveillance and Prevention Network (RNV3P)   (France)

Author keywords

Data mining; Occupational diseases; Occupational diseases network or database; Pharmacovigilance methods

Indexed keywords

EID: 84879383539     PISSN: 20937911     EISSN: 20937997     Source Type: Journal    
DOI: 10.5491/SHAW.2012.3.2.92     Document Type: Conference Paper

References (21)

1. The European Union Scientific Committee on Emerging and Newly Identified Health Risks (SCENHIR). Emerging Issues and the role of SCENHIR. Position paper adopted at the SCENHIR 28th Plenary [Internet]. Brussels (Belgium): SCENHIR. 2009 [cited 2011 Sep 1]. Available from: http://ec.europa.eu/health/ph-risk/ committees/04-scenihr/docs/scenihr-s-01.pdf.
2. Carder M, McNamee R, Turner S, Hussey L, Money A, Agius R. Improving estimates of specialist-diagnosed, workrelated respiratory and skin disease. Occup Med (Lond) 2011;61:33-9.
3. Hussey L, Turner S, Thorley K, McNamee R, Agius R. Comparison of work-related ill health reporting by occupational physicians and general practitioners. Occup Med (Lond) 2010;60:294-300.
4. McNamee R, Chen Y, Hussey L, Agius R. Time-sampled versus continuous-time reporting for measuring incidence. Epidemiology 2010;21:376-8.
5. Stocks SJ, McNamee R, Carder M, Agius RM. The incidence of medically reported work-related ill health in the UK construction industry. Occup Environ Med 2010;67:574-6.
6. Bonneterre V, Bicout D, Bernardet C, Dupas D, de Clavière C, de Gaudemaris R; RNV3P. The National Occupational illness surveillance and Prevention Network (RNV3P) and health monitoring. Sante Publique 2008;20(Suppl 3):S201-10. French.
7. Bonneterre V, de Gaudemaris R, Celse M, Chamoux A. Réseau national de vigilance des pathologies professionnelles: premier bilan et perspectives. Arch Mal Prof Env 2006;5:719-23. French.
8. Bonneterre V, Faisandier L, Bicout D, Bernardet C, Piollat J, Ameille J, de Clavière C, Aptel M, Lasfargues G, de Gaudemaris R; RNV3P. Programmed health surveillance and detection of emerging diseases in occupational health: contribution of the French national occupational disease surveillance and prevention network (RNV3P). Occup Environ Med 2010;67:178-86.
9. Bonneterre V. Detection and investigation of potential emerging occupational diseases using the French National Occupational Disease Surveillance and Prevention Network [PhD dissertation thesis]. Grenoble (France): Université de Grenoble; 2010.
10. Watson WA, Litovitz TL, Belson MG, Wolkin AB, Patel M, Schier JG, Reid NE, Kilbourne E, Rubin C. The toxic exposure surveillance system (TESS): risk assessment and real-time toxicovigilance across United States poison centers. Toxicol Appl Pharmacol 2005;207(2 Suppl):604-10.
11. Henning KJ. What is syndromic surveillance? MMWR Morb Mortal Wkly Rep 2004;53 (Suppl):5-11.
12. Wagner MM, Espino J, Tsui FC, Gesteland P, Chapman W, Ivanov O, Moore A, Wong W, Dowling J, Hutman J. Syndrome and outbreak detection using chief-complaint data-experience of the Real-Time Outbreak and Disease Surveillance project. MMWR Morb Mortal Wkly Rep 2004;53 (Suppl):28-31.
13. Lindquist M, Edwards IR, Bate A, Fucik H, Nunes AM, Ståhl M. From association to alert-a revised approach to international signal analysis. Pharmacoepidemiol Drug Saf 1999;8 (Suppl 1):S15-25.
14. Wilson AM, Thabane L, Holbrook A. Application of data mining techniques in pharmacovigilance. Br J Clin Pharmacol. 2004;57:127-34.
15. Hauben M, Bate A. Decision support methods for the detection of adverse events in post-marketing data. Drug Discov Today 2009;14:343-57.
16. Bonneterre V, Bicout DJ, Larabi L, Bernardet C, Maitre A, Tubert-Bitter P, de Gaudemaris R. Detection of emerging diseases in occupational health: usefulness and limitations of the application of pharmacosurveillance methods to the database of the French National Occupational Disease Surveillance and Prevention network (RNV3P). Occup Environ Med 2008;65:32-7.
17. Roux E, Thiessard F, Fourrier A, Bégaud B, Tubert-Bitter P. Evaluation of statistical association measures for the automatic signal generation in pharmacovigilance. IEEE Trans Inf Technol Biomed 2005;9:518-27.
18. van Puijenbroek EP, Bate A, Leufkens HG, Lindquist M, Orre R, Egberts AC. A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions. Pharmacoepidemiol Drug Saf 2002;11:3-10.
19. Szarfman A, Machado SG, O'Neill RT. Use of screening algorithms and computer systems to efficiently signal higherthan-expected combinations of drugs and events in the US FDA's spontaneous reports database. Drug Saf 2002;25:381-92.
20. Hauben M, Reich L, Chung S. Postmarketing surveillance of potentially fatal reactions to oncology drugs: potential utility of two signal-detection algorithms. Eur J Clin Pharmacol 2004;60:747-50.
21. Faisandier L, Bonneterre V, De Gaudemaris R, Bicout DJ. Occupational exposome: a network-based approach for characterizing Occupational Health Problems. J Biomed Inform 2011;44:545-52.