Naturalistic outcomes of community treatment orders: Antipsychotic long-acting injections versus oral medication

Journal of Psychopharmacology

Volumn 27, Issue 7, 2013, Pages 629-637

  Patel, Maxine X ^a   Matonhodze, Jane ^b   Baig, Mirza K ^c   Taylor, David ^c   Szmukler, George ^a   David, Anthony S ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF GREENWICH   (United Kingdom)

^c SOUTH LONDON AND MAUDSLEY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Antipsychotic drug; clinical outcome; community treatment order; delayed action; drug formulation; hospitalisation; legislation; long acting injection; schizophrenia

Indexed keywords

ANTIDEPRESSANT AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; BENZODIAZEPINE DERIVATIVE; CLOZAPINE; LONG ACTING DRUG; MOOD STABILIZER; NEUROLEPTIC AGENT; PSYCHOTROPIC AGENT;

ADOLESCENT; ADULT; AGED; ARTICLE; BIPOLAR DISORDER; COHORT ANALYSIS; COMMUNITY CARE; CONTROLLED STUDY; DEMOGRAPHY; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; FEMALE; FOLLOW UP; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH CARE; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PHARMACEUTICAL CARE; PRESCRIPTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PSYCHOSIS; SAMPLING; SCHIZOAFFECTIVE PSYCHOSIS; TREATMENT RESPONSE; UNITED KINGDOM;

ANTIPSYCHOTIC DRUG; CLINICAL OUTCOME; COMMUNITY TREATMENT ORDER; DELAYED ACTION; DRUG FORMULATION; HOSPITALISATION; LEGISLATION; LONG ACTING INJECTION; SCHIZOPHRENIA;

ADMINISTRATION, ORAL; ADULT; ANTIPSYCHOTIC AGENTS; COHORT STUDIES; COMMUNITY MENTAL HEALTH SERVICES; ENGLAND; FEMALE; HOSPITALIZATION; HUMANS; INJECTIONS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; TREATMENT OUTCOME; WALES; YOUNG ADULT;

EID: 84879352910     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881113486717     Document Type: Article

References (35)

1. Bindman J. Compulsion and freedom. Psychiatry. 2004 ; 3: 32-36
2. Brookes G, Brindle N. Compulsion in the community? The introduction of supervised community treatment. Adv Psych Treatment. 2010 ; 16: 242-252
3. Brown R, Taylor M, Mackay K, et al. Community compulsion in Scotland: A descriptive analysis. Psychiatrist. 2012 ; 36: 205-207
4. Burns T, Rugkasa J, Molodynski A, et al. Community treatment orders for patients with psychosis (OCTET): a randomised controlled trial. The Lancet. 2013 ; 376: 1670-1681
5. Care Quality Commission (2010) Monitoring the use of the Mental Health Act in 2009/10. Available at: www.cqc.org.uk/sites/default/files/media/ documents/cqc-monitoring-the-use-of-the-mental-health-act-in-200910-main-report- tagged.pdf (accessed 5 March 2012).
6. Churchill R, Owen G, Singh S, et al International Experiences of Community Treatment Orders. London: Institute of Psychiatry ; 2007
7. Department of Health (2007). Mental health Act 2007. Available at: www.legislation.gov.uk/ukpga/2007/12/pdfs/ukpga-20070012-en.pdf (accessed 5 March 2012).
8. Dye S, Dannaram S, Loynes B, et al. Supervised community treatment: Two-year follow-up study in Suffolk. Psychiatrist. 2012 ; 36: 298-302
9. Evans R, Makala J, Humphreys M, et al. Supervised community treatment - The first 6 months in Birmingham and Solihull. Psychiatrist. 2010 ; 34: 330-333
10. Frank D, Perry JC, Kean D, et al. Effects of compulsory treatment orders on time to hospital admission. Psychiatric Serv. 2005 ; 56: 867-869
11. Gould M. Hazards of a health safeguard. The Guardian. 2009 ;:
12. Haddad PM, Tiihonen J, Haukka J, et al. The place of observational studies in assessing the effectiveness of depot antipsychotics. Schizophr Res. 2011 ; 131: 260-261
13. Kisely S, Campbell LA, Preston N. Compulsory community and involuntary outpatient treatment for people with severe mental disorders. Cochrane Database Syst Rev. 2005 ;:
14. Lambert TJ, Singh BS, Patel MX. Community treatment orders and antipsychotic long-acting injections. Br J Psychiatry. 2009 ; 195: S57-62
15. Leucht C, Heres S, Kane JM, et al. Oral versus depot antipsychotic drugs for schizophrenia -A critical systematic review and meta-analysis of randomised long-term trials. Schizophr Res. 2011 ; 127: 82-92
16. Macpherson R, Molodynski A, Freeth R, et al. Supervised community treatment: Guidance for clinicians. Adv Psych Treatment. 2010 ; 16: 253-259
17. Muirhead DR, Ingram G, Harvey C. Effectiveness of community treatment orders for treatment of schizophrenia with oral or depot antipsychotic medication: Clinical outcomes. Aus NZ Psychiatry. 2006 ; 40: 596-605
18. Munetz MR, Grande T, Kleist J, et al. The effectiveness of outpatient civil commitment. Psychiatric Serv. 1996 ; 47: 1251-1253
19. O'Brien AA, Farrelle SJ. Community treatment orders: Profile of Canadian experience. Can J Psychiatry. 2005 ; 50: 27-30
20. O'Brien AJ, Mckenna BG, Kydd RR. Compulsory community mental health treatment: Literature review. Int J Nursing Studies. 2009 ; 46: 1245-1255
21. Office for National Statistics (2001) 2001 census: Census area statistics - ethnic group (UV09) data. Available at: http://neighbourhood.statistics.gov. uk/dissemination (accessed 5 March 2012).
22. Olfson M, Marcus SC, Ascher-Svanum H. Treatment of schizophrenia with long-acting fluphenazine, haloperidol, or risperidone. Schiz Bull. 2007 ; 33: 1379-1387
23. Patel MX, David AS. Why aren't depots prescribed more often, and what can be done about it?. Adv Psych Treatment. 2005 ; 11: 203-213
24. Patel MX, Matonhodze J, Baig MK, et al. Increased use of antipsychotic long-acting injections with community treatment orders. Therapeut Adv Psychopharmacol. 2011 ; 1: 37-45
25. Patel MX, Taylor M, David AS. Antipsychotic long-acting injections - Mind the gap. Br J Psychiatry. 2009 ; 195: S1-4
26. Rohland B, Rohrer J, Richards C. The long term effect of out-patient commitment on service use. Admin Policy Ment Health Ment Health Serv Res. 2000 ; 27: 383-394
27. Rosenheck RA, Krystal JH, Lew R, et al. Long-acting risperidone and oral antipsychotics in unstable schizophrenia. N Engl J Med. 2011 ; 364: 842-851
28. Royal Pharmaceutical Society (2008) British National Formulary. London: Royal Pharmaceutical Society of Great Britain.
29. Segal SP, Burgess PM. The utility of extended outpatient civil commitment. Int J Law Psychiatry. 2006 ; 29: 525-534
30. Steadman HJ, Gounis K, Dennis D, et al. Assessing the New York City involuntary outpatient commitment pilot program. Psychiatric Serv. 2001 ; 52: 330-336
31. Swartz MS, Swanson JW, Wagner HR, et al. Can involuntary outpatient commitment reduce hospital recidivism? Finding from a randomized trial with severely mentally ill individuals. Am J Psychiatry. 1999 ; 156: 1968-1975
32. Taylor M. Community treatment orders and their use in the UK. Adv Psych Treatment. 2010 ; 16: 260-262
33. Tiihonen J, Haukka J, Taylor M, et al. A nationwide cohort study of oral and depot antipsychotics after first hospitalisation for schizophrenia. Am J Psychiatry. 2011 ; 168: 603-609
34. Vaughn K, McConaghy N, Wolf C, et al. Community treatment orders: Relationship to clinical care, medication compliance, behavioural disturbance and readmission. Aus NZ J Psychiatry. 2000 ; 34: 801-808
35. World Health Organisation (1992) The International Classification of Diseases, version 10: Classification of mental and behavioural disorders: Clinical descriptions and diagnostic guidelines (ICD-10). Geneva: WHO ; 1992 :