The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury
Sandanger Ø, Ranheim T, Vinge LE, Bliksoen M, Alfsnes K, Finsen AV et al. The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury. Cardiovasc Res 2013;99: 164-174
Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury
Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Morimoto H et al. Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation 2011;123:594-604
The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse
Mezzaroma E, Toldo S, Farkas D, Seropian IM, Van Tassell BW, Salloum FN et al. The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse. Proc Natl Acad Sci USA 2011;108:19725-19730
Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signaling
Zuurbier CJ, Jong WM, Eerbeek O, Koeman A, Pulskens WP, Butter LM et al. Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signaling. PloS One 2012;7:e40643
Increased expression of monocarboxylate transporter 1 after acute ischemia of isolated, perfused mouse hearts
MartinovV, Rizvi SM,Weiseth SA, Sagave J, Bergersen LH, Valen G. Increased expression of monocarboxylate transporter 1 after acute ischemia of isolated, perfused mouse hearts. Life Sci 2009;85:379-385
Activation of liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia-reperfusion injury
Lei P, Baysa A, Nebb HI, Valen G, Skomedal T, Osnes JB et al. Activation of liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia-reperfusion injury. Basic Res Cardiol 2013;108: 323
An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury
Shigeoka AA, Mueller JL, Kambo A, Mathison JC, King AJ, Hall WF et al. An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury. J Immunol 2010;185:6277-6285