Putative conformations of the receptor-binding domain in S protein of hCoV-EMC in complex with its receptor dipeptidyl peptidase-4

Journal of Infection

Volumn 67, Issue 2, 2013, Pages 156-158

  Jiang, Shibo ^a   Lu, Lu ^a   Du, Lanying ^b   Debnath, Asim K ^b  

^a FUDAN UNIVERSITY   (China)

^b NEW YORK BLOOD CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; VIRUS PROTEIN; VITRONECTIN;

ALPHA HELIX; BINDING KINETICS; BINDING SITE; COMPLEX FORMATION; COMPUTER PROGRAM; CORONAVIRUS; FOURIER TRANSFORMATION; HUMAN BETACORONAVIRUS EMC; LETTER; MOLECULAR DOCKING; NONHUMAN; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; SARS CORONAVIRUS; SEQUENCE HOMOLOGY;

EID: 84879320515     PISSN: 01634453     EISSN: 15322742     Source Type: Journal    
DOI: 10.1016/j.jinf.2013.04.007     Document Type: Letter

References (12)

1. Jiang S., Lu L., Du L., Debnath A.K. A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC. J Infect 2013, 66:464-466.
2. Li F., Li W.H., Farzan M., Harrison S.C. Structure of SARS coronavirus spike receptor-binding domain complexed with receptor. Science 2005, 309:1864-1868.
3. Prabakaran P., Gan J., Feng Y., Zhu Z., Choudhry V., Xiao X., et al. Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody. J Biol Chem 2006, 281:15829-15836.
4. Muller M.A., Raj V.S., Muth D., Meyer B., Kallies S., Smits S.L., et al. Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines. MBio 2012, 3.
5. Raj V.S., Mou H., Smits S.L., Dekkers D.H., Muller M.A., Dijkman R., et al. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature 2013, 495:251-254.
6. Oefner C., D'Arcy A., Mac S.A., Pierau S., Gardiner R., Dale G.E. High-resolution structure of human apo dipeptidyl peptidase IV/CD26 and its complex with 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)-acetyl]-2-cyano-(S)-pyrrolidine. Acta Crystallogr D Biol Crystallogr 2003, 59:1206-1212.
7. Comeau S.R., Kozakov D., Brenke R., Shen Y., Beglov D., Vajda S. ClusPro: performance in CAPRI rounds 6-11 and the new server. Proteins 2007, 69:781-785.
8. Kozakov D., Brenke R., Comeau S.R., Vajda S. PIPER: an FFT-based protein docking program with pairwise potentials. Proteins 2006, 65:392-406.
9. Ritchie D.W., Venkatraman V. Ultra-fast FFT protein docking on graphics processors. Bioinformatics 2010, 26:2398-2405.
10. Krissinel E., Henrick K. Inference of macromolecular assemblies from crystalline state. J Mol Biol 2007, 372:774-797.
11. WHO. Novel coronavirus infection - update. 3-26-2013. http://www.who.int/csr/don/2013_03_26/en/index.html.
12. Evidence of person-to-person transmission within a family cluster of novel coronavirus infections, United Kingdom, February 2013. Euro Surveill 2013, 18. The Health Protection Agency (HPA) UK Novel Coronavirus Investigation team, pii=20427.