Improving the outcome of a Marek's disease challenge in multiple lines of egg type chickens

Avian Diseases

Volumn 57, Issue 2 SUPPL. 1, 2013, Pages 519-522

  Fulton, J E ^a   Arango, J ^a   Arthur, J A ^a   Settar, P ^a   Kreager, K S ^a   O'Sullivan, N P ^a  

^a Hy Line International   (United States)

Author keywords

Egg type chickens; Genetic resistance; MDV challenge; MHC haplotype

Indexed keywords

ANIMAL; ARTICLE; BIRD DISEASE; CHICKEN; FEMALE; GENETIC SELECTION; GENETICS; HAPLOTYPE; IMMUNOLOGY; MAJOR HISTOCOMPATIBILITY COMPLEX; MARDIVIRUS; MAREK DISEASE; MORTALITY; VIROLOGY;

ANIMALS; CHICKENS; FEMALE; HAPLOTYPES; MAJOR HISTOCOMPATIBILITY COMPLEX; MARDIVIRUS; MAREK DISEASE; POULTRY DISEASES; SELECTION, GENETIC;

AVES; GALLUS GALLUS;

EID: 84879313709     PISSN: 00052086     EISSN: None     Source Type: Journal    
DOI: 10.1637/10408-100212-Reg.1     Document Type: Article

References (16)

1. Bacon, L. D. Influence of the major histocompatibility complex on disease resistance and productivity. Poult. Sci. 66:802-811. 1987.
2. Biggs, P. M., and V. Nair. The long view: 40 years of Marek's disease research and avian pathology. Avian Pathol. 41:1, 3-9. 2012.
3. Briles, W. E., H. A. Stone, and R. K. Cole. Marek's disease: Effect of B histocompatibility alloalleles in resistant and susceptible lines. Science 195:193-195. 1977.
4. Cole, R. K. Studies on genetic resistance to Marek's disease. Avian Dis. 12:9-28. 1968.
5. Fulton, J. E., H. R. Juul-Madsen, C. M. Ashwell, A. M. McCarron, J. A. Arthur, N. P. O'Sullivan, and R. L. Taylor Jr. Molecular genotype identification of the Gallus gallus major histocompatibility complex. Immunogenetics 58:407-421. 2006.
6. Heifetz, E. M., J. E. Fulton, N. P. O'Sullivan, J. A. Arthur, H. Cheng, J. Wang, M. Soller, and J. C. M. Dekkers. Mapping QTL affecting resistance to Marek's disease in an F6 advanced intercross population of commercial layer chickens. BMC Genomics 10:20. 2009.
7. Heifetz, E. M., J. E. Fulton, N. P. O'Sullivan, J. A. Arthur, J. Wang, J. C. M. Dekkers, and M. Soller. Mapping quantitative trait loci affecting susceptibility to Marek's disease virus in a backcross population of layer chickens. Genetics 177:2417-2431. 2007.
8. Kuhnlein, U., L. Ni, S. Weigend, J. S. Gavora, W. Fairfull, and D. Zadworny. DNA polymorphisms in the chicken growth hormone gene: Response to selection for disease resistance and association with egg production. Anim. Genet. 28:116-123. 1997.
9. Li, D. F., L. Lian, L. J. Qu, M. Chen, W. B. Liu, S. R. Chen, J. X. Zheng, G. Y. Xu, and N. Yang. A genome-wide SNP scan reveals two loci associated with the chicken resistance to Marek's disease. Anim. Genet. doi:10.1111/j.1365-2052.2012.02395.x [Epub ahead of print]. 2012.
10. Liu, H. C., H. J. Kung, J. E. Fulton, R. W. Morgan, and H. H. Cheng. Growth hormone interacts with the Marek's disease virus SORF2 protein and is associated with disease resistance in chicken. Proc. Natl. Acad. Sci. U. S. A. 98:9203-9208. 2001.
11. Liu, H. C., M. Niikura, J. Fulton, and H. H. Cheng. Identification of chicken lymphocyte antigen 6 complex, locus E (LY6E, alias SCA2) as a putative Marek's disease resistance gene via a virus-host protein interaction screen. Cytogenet. Genome Res. 102:304-308. 2003.
12. Rauw, W. M., E. Kanis, E. N. Noordhuizen-Stassen, and F. J. Grommers. Undesirable side effects of selection for high production efficiency in farm animals: A review. Livestock Prod. Sci. 56:15-33. 1998.
13. Smith, J., J. R. Sadeyen, I. R. Paton, P. M. Hocking, N. Salmon, M. Fife, V. Nair, D. W. Burt, and P. Kaiser. Systems analysis of immune responses in Marek's disease virus-infected chickens identified a gene involved in susceptibility and highlights a novel pathogenicity mechanism. J. Virol. 85:11146-11158. 2010.
14. Vallejo, R. L., L. D. Bacon, H. C. Liu, R. L. Witter, M. A. Groenen, J. Hillel, and H. H. Cheng. Genetic mapping of quantitative trait loci affecting susceptibility to Marek's disease virus induced tumors in F2 intercross chickens. Genetics 148:349-360. 1998.
15. Witter, R. L. Increased virulence of Marek's disease virus field isolates. Avian Dis. 41:149-163. 1997.
16. Yonash, N., L. D. Bacon, R. L. Witter, and H. H. Cheng. High resolution mapping and identification of new quantitative trait loci (QTL) affecting susceptibility to Marek's disease. Anim. Genet. 30:126-135. 1999.