3D visualization of epidermal langerhans cells

Methods in Molecular Biology

Volumn 961, Issue , 2013, Pages 119-127

  Kubo, Akiharu ^a   Nagao, Keisuke ^a   Amagai, Masayuki ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Langerhans cells; Skin resident dendritic cells; Stratum corneum; Tight junction

Indexed keywords

ANIMAL CELL; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; DERMIS; EAR; EPIDERMIS CELL; IMMUNOFLUORESCENCE; LANGERHANS CELL; MICROENVIRONMENT; MOLECULAR DYNAMICS; MOLECULAR IMAGING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN SURFACE; TIGHT JUNCTION; ANIMAL; C57BL MOUSE; CONFOCAL MICROSCOPY; CYTOLOGY; EPIDERMIS; FLUORESCENT ANTIBODY TECHNIQUE; HISTOLOGY; METHODOLOGY; ULTRASTRUCTURE;

ANIMALS; EPIDERMIS; FLUORESCENT ANTIBODY TECHNIQUE; HISTOCYTOLOGICAL PREPARATION TECHNIQUES; LANGERHANS CELLS; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; TIGHT JUNCTIONS;

MLCS; MLOWN;

EID: 84879296887     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-227-8_5     Document Type: Article

References (24)

1. Langerhans P (1868) Ueber die Nerven der menschlichen Haut. Virchows Arch 44:325-338
2. Bergstresser PR, Toews GB, Streilein JW (1980) Natural and perturbed distributions of Langerhans cells: responses to ultraviolet light, heterotopic skin grafting, and dinitro fluorobenzene sensitization. J Invest Dermatol 75:73-77
3. Zimmerli S, Hauser C (2007) Langerhans cells and lymph node dendritic cells express the tight junction component claudin-1. J Invest Dermatol 127:2381-2390
4. Merad M, Ginhoux F, Collin M (2008) Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells. Nat Rev Immunol 8:935-947
5. Kubo A, Nagao K, Yokouchi M, Sasaki H, Amagai M (2009) External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers. J Exp Med 206:2937-2946
6. Kaplan DH (2010) In vivo function of Langerhans cells and dermal dendritic cells. Trends Immunol 31:446-451
7. Nagao K, Ginhoux F, Leitner WW, Motegi S, Bennett CL, Clausen BE, Merad M, Udey MC (2009) Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions. Proc Natl Acad Sci U S A 106:3312-3317
8. Thomas WR, Edwards AJ, Watkins MC, Asherson GL (1980) Distribution of immunogenic cells after painting with the contact sensitizers fluorescein isothiocyanate and oxazolone. Different sensitizers form immunogenic complexes with different cell populations. Immunology 39:21-27
9. Larsen CP, Steinman RM, Witmer-Pack M, Hankins DF, Morris PJ, Austyn JM (1990) Migration and maturation of Langerhans cells in skin transplants and explants. J Exp Med 172:1483-1493
10. Nishibu A, Ward BR, Jester JV, Ploegh HL, Boes M, Takashima A (2006) Behavioral responses of epidermal Langerhans cells in situ to local pathological stimuli. J Invest Dermatol 126:787-796
11. Kubo A, Nagao K, Amagai M (2011) Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases. J Clin Invest 122:440-447
12. McGrath JA, Uitto J (2008) The filaggrin story: novel insights into skin-barrier function and disease. Trends Mol Med 14:20-27
13. Oyoshi MK, He R, Kumar L, Yoon J, Geha RS (2009) Cellular and molecular mechanisms in atopic dermatitis. Adv Immunol 102:135-226
14. Medawar P (1941) Sheets of pure epidermal epithelium from human skin. Nature 148:783
15. Felsher Z (1947) Studies on the adherence of the epidermis to the corium. J Invest Dermatol 8:35-47
16. Diaz LA, Heaphy MR, Calvanico NJ, Tomasi TB, Jordon RE (1977) Separation of epidermis from dermis with sodium thiocyanate. J Invest Dermatol 68:36-38
17. Blank IH, Miller OG (1950) A method for the separation of the epidermis from the dermis. J Invest Dermatol 15:9-10
18. Van Scott EJ (1952) Mechanical separation of the epidermis from the corium. J Invest Dermatol 18:377-379
19. Mackenzie IC, Squier CA (1975) Cytochemical identification of ATPase-positive langerhans cells in EDTA-separated sheets of mouse epidermis. Br J Dermatol 92:523-533
20. Juhlin L, Shelley WB (1977) New staining techniques for the Langerhans cell. Acta Derm Venereol 57:289-296
21. Nordlund JJ, Ackles A (1981) A method for quantifying Langerhans cells in epidermal sheets of human and murine skin. Tissue Antigens 17:217-225
22. Caughman SW, Sharrow SO, Shimada S, Stephany D, Mizuochi T, Rosenberg AS, Katz SI, Singer A (1986) Ia+ murine epidermal Langerhans cells are deficient in surface expression of the class I major histocompatibility complex. Proc Natl Acad Sci U S A 83:7438-7442
23. Itoh M, Yonemura S, Nagafuchi A, Tsukita SA, Tsukita SH (1991) A 220-kD undercoatconstitutive protein: its specific localization at cadherin-based cell-cell adhesion sites. J Cell Biol 115:1449-1462
24. Itoh M, Nagafuchi A, Yonemura S, Kitani-Yasuda T, Tsukita SA, Tsukita SH (1993) The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy.J Cell Biol 121:491-502