Reply to Mottershead et al.: GDF9:BMP15 heterodimers are potent regulators of ovarian functions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 25, 2013, Pages

  Peng, Jia ^a   Li, Qinglei ^a   Wigglesworth, Karen ^a   Rangarajan, Adithya ^a   Kattamuri, Chandramohan ^a   Peterson, Randall T ^b   Eppigg, John J ^a   Thompson, Thomas B ^a   Matzuk, Martin M ^a,c,d,e  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c JACKSON LABORATORY   (United States)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 15; GROWTH DIFFERENTIATION FACTOR 9; HETERODIMER; HOMODIMER;

GRANULOSA CELL; HUMAN; IN VITRO STUDY; LETTER; MOLECULAR EVOLUTION; NONHUMAN; OOCYTE; OVARY FOLLICLE DEVELOPMENT; OVARY FUNCTION; PREDICTION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SHEEP; SIGNAL TRANSDUCTION; SILVER STAINING;

ANIMALS; BONE MORPHOGENETIC PROTEIN 15; FEMALE; GROWTH DIFFERENTIATION FACTOR 9; HUMANS; OVARY;

EID: 84879286287     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1304497110     Document Type: Letter

References (6)

1. Mottershead DG, et al. (2013) Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization. Proc Natl Acad Sci USA 110:E2257.
2. Peng J, et al. (2013) Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions. Proc Natl Acad Sci USA 110(8):E776-E785.
3. Li Q, Rajanahally S, Edson MA, Matzuk MM (2009) Stable expression and characterization of N-terminal tagged recombinant human bone morphogenetic protein 15. Mol Hum Reprod 15(12):779-788.
4. Yan C, et al. (2001) Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function. Mol Endocrinol 15(6):854-866.
5. Liao WX, Moore RK, Otsuka F, Shimasaki S (2003) Effect of intracellular interactions on the processing and secretion of bone morphogenetic protein-15(BMP-15) and growth and differentiation factor-9. Implication of the aberrant ovarian phenotype of BMP-15 mutant sheep. J Biol Chem 278 (6):3713-3719.
6. Li Q, et al. (2011) Transforming growth factor β receptor type 1 is essential for female reproductive tract integrity and function. PLoS Genet 7(10):e1002320. Human Development through R01