Soluble CD26/Dipeptidyl Peptidase IV Enhances the Transcription of IL-6 and TNF-α in THP-1 Cells and Monocytes

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Ikeda, Tetsurou ^a   Kumagai, Emi ^a   Iwata, Satoshi ^a   Yamakawa, Akio ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DIPEPTIDYL PEPTIDASE IV; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN C FOS; PROTEIN CUX1; PROTEIN P50; RECOMBINANT DIPEPTIDYL PEPTIDASE IV; RECOMBINANT ENZYME; SITAGLIPTIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; DPP4 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR;

ARTICLE; CELL ISOLATION; CELL NUCLEUS; CELL STIMULATION; CELL STRAIN; CELL STRAIN THP 1; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOSOL; GENE ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; MONOCYTE; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; ADULT; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; MALE; METABOLISM; TUMOR CELL LINE;

ADULT; CELL LINE, TUMOR; DIPEPTIDYL PEPTIDASE 4; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; MONOCYTES; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84879275383     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066520     Document Type: Article

References (23)

1. Fox DA, Hussey RE, Fitzgerald KA, Acuto O, Poole C, et al. (1984) Ta1, a novel 105 KD human T cell activation antigen defined by a monoclonal antibody. J Immunol 133: 1250-1256.
2. Nanus DM, Engelstein D, Gastl GA, Gluck L, Vidal MJ, et al. (1993) Molecular cloning of the human kidney differentiation antigen gp160: human aminopeptidase A. Proc Natl Acad Sci USA. 90: 7069-7073.
3. Tanaka T, Camerini D, Seed B, Torimoto Y, Dang NH, et al. (1992) Cloning and functional expression of the T cell activation antigen CD26. J Immunol 149: 481-486.
4. Fleischer B, (1994) CD26: a surface protease involved in T-cell activation. Immunol Today 15: 180-184.
5. Hegen M, Kameoka J, Dong RP, Schlossman SF, Morimoto C, (1997) Cross-linking of CD26 by antibody induces tyrosine phosphorylation and activation of mitogen-activated protein kinase. Immunology 90: 257-264.
6. Tanaka T, Kameoka J, Yaron A, Schlossman SF, Morimoto C, (1993) The costimulatory activity of the CD26 antigen requires dipeptidyl peptidase IV enzymatic activity. Proceedings of the National Academy of Sciences of the United States of America 90: 4586-4590.
7. Ohnuma K, Yamochi T, Uchiyama M, Nishibashi K, Yoshikawa N, et al. (2004) CD26 up-regulates expression of CD86 on antigen-presenting cells by means of caveolin-1. Proc Natl Acad Sci USA 101: 14186-14191.
8. Ohnuma K, Yamochi T, Uchiyama M, Nishibashi K, Iwata S, et al. (2005) CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells. Mol Cell Biol 25: 7743-7757.
9. Manickasingham SP, Anderton SM, Burkhart C, Wraith DC, (1998) Qualitative and quantitative effects of CD28/B7-mediated costimulation on naive T cells in vitro. J Immunol 161: 3827-3835.
10. Ikushima H, Munakata Y, Ishii T, Iwata S, Terashima M, et al. (2000) Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation. Proc Natl Acad Sci USA 97: 8439-8444.
11. Chomczynski P, Sacchi N, (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159.
12. Ponticos M, Harvey C, Ikeda T, Abraham D, Bou-Gharios G, (2009) JunB mediates enhancer/promoter activity of COL1A2 following TGF-{beta} induction. Nucleic Acids Res 37: 5378-5389.
13. Takeda K, Akira S, (2004) TLR signaling pathways. Semin Immunol 16: 3-9.
14. Koga K, Takaesu G, Yoshida R, Nakaya M, Kobayashi T, et al. (2009) Cyclic adenosine monophosphate suppresses the transcription of proinflammatory cytokines via the phosphorylated c-Fos protein. Immunity 30: 372-383.
15. Sinclair AM, Lee JA, Goldstein A, Xing D, Liu S, et al. (2001) Lymphoid apoptosis and myeloid hyperplasia in CCAAT displacement protein mutant mice. Blood 98: 3658-3667.
16. Morimoto C, Schlossman SF, (1998) The structure and function of CD26 in the T-cell immune response. Immunol Rev 161: 55-70.
17. Proost P, De Meester I, Schols D, Struyf S, Lambeir AM, et al. (1998) Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection. J Biol Chem 273: 7222-7227.
18. Kahne T, Neubert K, Faust J, Ansorge S, (1998) Early phosphorylation events induced by DPIV/CD26-specific inhibitors. Cell Immunol 189: 60-66.
19. Kubota T, Flentke GR, Bachovchin WW, Stollar BD, (1992) Involvement of dipeptidyl peptidase IV in an in vivo immune response. Clin Exp Immunol 89: 192-197.
20. Korom S, De Meester I, Stadlbauer TH, Chandraker A, Schaub M, et al. (1997) Inhibition of CD26/dipeptidyl peptidase IV activity in vivo prolongs cardiac allograft survival in rat recipients. Transplantation 63: 1495-1500.
21. Oravecz T, Pall M, Roderiquez G, Gorrell MD, Ditto M, et al. (1997) Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage. Journal Exp Med 186: 1865-1872.
22. Tanaka T, Duke-Cohan JS, Kameoka J, Yaron A, Lee I, et al. (1994) Enhancement of antigen-induced T-cell proliferation by soluble CD26/dipeptidyl peptidase IV. Proc Natl Acad Sci USA 91: 3082-3086.
23. Casrouge A, Decalf J, Ahloulay M, Lababidi C, Mansour H, et al. (2011) Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV. J Clin Invest 121: 308-17.