Heme Oxygenase-1 Regulates Matrix Metalloproteinase MMP-1 Secretion and Chondrocyte Cell Death via Nox4 NADPH Oxidase Activity in Chondrocytes

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Rousset, Francis ^a   Nguyen, Minh Vu Chuong ^a   Grange, Laurent ^a,b   Morel, Françoise ^a   Lardy, Bernard ^a,c  

^a UNIV GRENOBLE ALPES   (France)

^b Hopital Sud CHU de Grenoble   (France)

^c GRENOBLE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; CELL DNA; HEME; HEME OXYGENASE 1; HETERODIMER; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; PROTEIN P22; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SUCCINYLACETONE;

APOPTOSIS; ARTICLE; BIODEGRADATION; CARTILAGE CELL; CATABOLISM; CELL ACTIVATION; CELL STRAIN; CELL STRAIN C 20; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME LOCALIZATION; ENZYME REGULATION; ENZYME RELEASE; HEME SYNTHESIS; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; SIGNAL TRANSDUCTION;

APOPTOSIS; CARBON MONOXIDE; CHONDROCYTES; DNA FRAGMENTATION; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HEME; HEME OXYGENASE-1; HUMANS; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 1; NADPH OXIDASE; OSTEOARTHRITIS; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS;

EID: 84879260319     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066478     Document Type: Article

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