Influence of Bcl-1 gene polymorphism of glucocorticoid receptor gene (NR3C1, rs41423247) on blood pressure, glucose in Northern Indians

Indian Journal of Clinical Biochemistry

Volumn 26, Issue 2, 2011, Pages 125-130

  Srivastava, Neena ^a   Prakash, Jai ^a   Lakhan, Ram ^b   Agarwal, C G ^a   Pant, D C ^a   Mittal, Balraj ^b  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

^b SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Abdominal obesity; Glucocorticoid receptors; Polymorphism; Risk

Indexed keywords

EID: 84879257545     PISSN: 09701915     EISSN: 09740422     Source Type: Journal    
DOI: 10.1007/s12291-010-0099-6     Document Type: Article

References (28)

1. James WP. The epidemiology of obesity: the size of the problem. J Intern Med. 2008;263:336-52. (Pubitemid 351342683)
2. Flegal MD, Carroll RJ, Kuczmarki RJ. Overweight and obesity in the united state: prevalence and trends, 1960-1994. Int J Obes Eelat Metab Disord. 1998;22:39-47.
3. Rosmond R, Chagnon YC, Holm G, Chagnon M, Perusse L, Lindell K, et al. A glucocorticoid receptor gene marker is associated with abdominal obesity, leptin, and dysregulation of the hypothalamic-pituitary-adrenal axis. Obes Res. 2000;8:211-8.
4. Deurenberg P, Hautvast JG. Prevalence of overweight and obesity in the Netherlands in relation to sociodemographic variables, lifestyle and eating behavior: starting points for the prevention and treatment of obesity. Bibl Nutr Dieta. 1998;44:8-21.
5. Misra A, Wasir JS, Pandey RM. An evaluation of candidate definitions of the metabolic syndrome in adult Asian Indians. Diabetes Care. 2005;28:398-403. (Pubitemid 40170946)
6. Dallman MF, Strack AM, Akana SF, Bradbury MJ, Hanson ES, Scribner KA, et al. Feast and famine: critical role of glucocorticoids with insulin in daily energy flow. Front Neuroendocrinol. 1993;14:303-47. (Pubitemid 23321823)
7. Dallman MF, Akana SF, Strack AM, Hanson ES, Sebastian RJ. The neural network that regulates energy balance is responsive to glucocorticoids and insulin and also regulates HPA axis responsivity at a site proximal to CRF neurons. Ann N Y Acad Sci. 1995;771:730-42. (Pubitemid 26077449)
8. Bjorntorp P, Rosmond R. Obesity and cortisol. Nutrition. 2000;16:924-36.
9. van Rossum EF, Koper JW, van den Beld AW, Uitterlinden AG, Arp P, Ester W, et al. Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index. Clin Endocrinol (Oxf). 2003;59:585-92. (Pubitemid 37357618)
10. Fleury I, Beaulieu P, Primeau M, Labuda D, Sinnett D, Krajinovic M. Characterization of the BclI polymorphism in the glucocorticoid receptor gene. Clin Chem. 2003;49:1528-31. (Pubitemid 37011745)
11. Weaver JU, Hitman GA, Kopelman PG. An association between a Bc1I restriction fragment length polymorphism of the glucocorticoid receptor locus and hyperinsulinaemia in obese women. J Mol Endocrinol. 1992;9:295-300.
12. Clement K, Philippi A, Jury C. Candidate gene approach of familial morbid obesity: linkage analysis of the glucocorticoid receptor gene. Int J Obes Relat Metab Disord. 1996;20:507-12. (Pubitemid 26174334)
13. Buemann B, Vohl MC, Chagnon M, Chagnon YC, Gagnon J, Perusse L, et al. Abdominal visceral fat is associated with a BclI restriction fragment length polymorphism at the glucocorticoid receptor gene locus. Obes Res. 1997;5:186-92. (Pubitemid 127702722)
14. Watt GC, Harrap SB, Foy CJ, Holton DW, Edwards HV, Davidson HR, et al. Abnormalities of glucocorticoid metabolism and the renin-angiotensin system: a four-corners approach to the identification of genetic determinants of blood pressure. J Hypertens. 1992;10:473-82.
15. Panarelli M, Holloway CD, Fraser R, Connell JM, Ingram MC, Anderson NH, et al. Glucocorticoid receptor polymorphism, skin vasoconstriction, and other metabolic intermediate phenotypes in normal human subjects. JClin EndocrinolMetab. 1998;83:1846-52. (Pubitemid 28496304)
16. Srivastava N, Achyut BR, Prakash J, Agarwal CG, Pant DC, Mittal B. Association of cholesteryl ester transfer protein (TaqIB) and apolipoprotein E (HhaI) gene variants with obesity. Mol Cell Biochem. 2008;314:171-7.
17. Young DS, Pestaner LC, Gibberman V. Effects of drugs on clinical laboratory tests. Clin Chem. 1975;21:1D-432D.
18. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16:1215.
19. Andrew R, Gale CR, Walker BR, Seckl JR, Martyn CN. Glucocorticoid metabolism and the metabolic syndrome: associations in an elderly cohort. Exp Clin Endocrinol Diabetes. 2002;110:284-90. (Pubitemid 35246745)
20. Rosmond R, Bjorntorp P. The interactions between hypothalamic-pituitary- adrenal axis activity, testosterone, insulin like growth factor I and abdominal obesity with metabolism and blood pressure in men. Int J Obes Relat Metab Disord. 1998;22:1184-96. (Pubitemid 28548539)
21. Fried SK, Russell CD, Grauso NL, Brolin RE. Lipoprotein lipase regulation by insulin and glucocorticoid in subcutaneous and omental adipose tissues of obese women and men. J Clin Invest. 1993;92:2191-8. (Pubitemid 23333523)
22. Linkowski P, Van Onderbergen A, Kerkhofs M, Bosson D, Mendlewicz J, Van Cauter E. Twin study of the 24-h cortisol profile: evidence for genetic control of the human circadian clock. Am J Physiol. 1993;264:E 173-81.
23. Ukkola O, Rosmond R, Tremblay A, Bouchard C. Glucocorticoid receptor Bcl I variant is associated with an increased atherogenic profile in response to long-term overfeeding. Atherosclerosis. 2001;157:221-4. (Pubitemid 32539374)
24. Morris BJ. Identification of essential hypertension genes. J Hypertens. 1993;11:115-20. (Pubitemid 23130562)
25. Kenyon CJ, Panarelli M, Zagato L, Torielli L, Heeley RP, Holloway CD, et al. Glucocorticoid receptor polymorphism in genetic hypertension. J Mol Endocrinol. 1998;21:41-50. (Pubitemid 28374880)
26. Lin RC, Wang WY, Morris BJ. Association and linkage analyses of glucocorticoid receptor gene markers in essential hypertension. Hypertension. 1999;34:1186-92. (Pubitemid 30002380)
27. Whitworth JA, Kelly JJ, Brown MA, Williamson PM, Lawson JA. Glucocorticoids and hypertension in man. Clin Exp Hypertens. 1997;19:871-84. (Pubitemid 27321710)
28. Kelly JJ, Mangos G, Williamson PM, Whitworth JA. The nitric oxide system and cortisol-induced hypertension in humans. Clin Exp Pharmacol Physiol. 1998;25:945-6. (Pubitemid 28500837)