메뉴 건너뛰기




Volumn 121, Issue 16, 2013, Pages 3181-3184

Naturally occurring oncogenic GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; TRANSCRIPTION FACTOR GATA 1;

EID: 84879247882     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-01-405746     Document Type: Article
Times cited : (20)

References (19)
  • 3
    • 35648968664 scopus 로고    scopus 로고
    • Acute megakaryoblastic leukemia in down syndrome
    • Hitzler JK. Acute megakaryoblastic leukemia in Down syndrome. Pediatr Blood Cancer. 2007;49 (7 Suppl):1066-1069.
    • (2007) Pediatr Blood Cancer , vol.49 , Issue.7 , pp. 1066-1069
    • Hitzler, J.K.1
  • 4
    • 63149148538 scopus 로고    scopus 로고
    • Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in down syndrome
    • Malinge S, Izraeli S, Crispino JD. Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome. Blood. 2009; 113(12):2619-2628.
    • (2009) Blood , vol.113 , Issue.12 , pp. 2619-2628
    • Malinge, S.1    Izraeli, S.2    Crispino, J.D.3
  • 6
    • 0141889275 scopus 로고    scopus 로고
    • Frequent mutations in the gata-1 gene in the transient myeloproliferative disorder of down syndrome
    • Xu G, Nagano M, Kanezaki R, et al. Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome. Blood. 2003;102(8):2960-2968.
    • (2003) Blood , vol.102 , Issue.8 , pp. 2960-2968
    • Xu, G.1    Nagano, M.2    Kanezaki, R.3
  • 7
    • 0042243593 scopus 로고    scopus 로고
    • Mutations in exon 2 of gata1 are early events in megakaryocytic malignancies associated with trisomy 21
    • Rainis L, Bercovich D, Strehl S, et al. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood. 2003;102(3):981-986.
    • (2003) Blood , vol.102 , Issue.3 , pp. 981-986
    • Rainis, L.1    Bercovich, D.2    Strehl, S.3
  • 8
    • 1842422317 scopus 로고    scopus 로고
    • The gata1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying down syndrome
    • Harigae H, Xu G, Sugawara T, Ishikawa I, Toki T, Ito E. The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome. Blood. 2004; 103(8):3242-3243.
    • (2004) Blood , vol.103 , Issue.8 , pp. 3242-3243
    • Harigae, H.1    Xu, G.2    Sugawara, T.3    Ishikawa, I.4    Toki, T.5    Ito, E.6
  • 9
    • 38949211469 scopus 로고    scopus 로고
    • Acute megakaryoblastic leukaemia (amkl) in children: A comparison of amkl with and without down syndrome
    • Hama A, Yagasaki H, Takahashi Y, et al. Acute megakaryoblastic leukaemia (AMKL) in children: a comparison of AMKL with and without Down syndrome. Br J Haematol. 2008;140(5):552-561.
    • (2008) Br J Haematol , vol.140 , Issue.5 , pp. 552-561
    • Hama, A.1    Yagasaki, H.2    Takahashi, Y.3
  • 10
    • 23044499360 scopus 로고    scopus 로고
    • Differential requirements for the activation domain and fog-interaction surface of gata-1 in megakaryocyte gene expression and development
    • Muntean AG, Crispino JD. Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development. Blood. 2005; 106(4):1223-1231.
    • (2005) Blood , vol.106 , Issue.4 , pp. 1223-1231
    • Muntean, A.G.1    Crispino, J.D.2
  • 11
    • 69849088569 scopus 로고    scopus 로고
    • Induction of hyperproliferative fetal megakaryopoiesis by an n-terminally truncated gata1 mutant
    • Shimizu R, Kobayashi E, Engel JD, Yamamoto M. Induction of hyperproliferative fetal megakaryopoiesis by an N-terminally truncated GATA1 mutant. Genes Cells. 2009;14(9): 1119-1131.
    • (2009) Genes Cells , vol.14 , Issue.9 , pp. 1119-1131
    • Shimizu, R.1    Kobayashi, E.2    Engel, J.D.3    Yamamoto, M.4
  • 12
    • 20044381309 scopus 로고    scopus 로고
    • Developmental stage-selective effect of somatically mutated leukemogenic transcription factor Gata1
    • Li Z, Godinho FJ, Klusmann JH, Garriga-Canut M, Yu C, Orkin SH. Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nat Genet. 2005; 37(6):613-619.
    • (2005) Nat Genet , vol.37 , Issue.6 , pp. 613-619
    • Li, Z.1    Godinho, F.J.2    Klusmann, J.H.3    Garriga-Canut, M.4    Yu, C.5    Orkin, S.H.6
  • 13
    • 78649492744 scopus 로고    scopus 로고
    • Down syndrome and gata1 mutations in transient abnormal myeloproliferative disorder: Mutation classes correlate with progression to myeloid leukemia
    • Kanezaki R, Toki T, Terui K, et al. Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder: mutation classes correlate with progression to myeloid leukemia. Blood. 2010;116(22):4631-4638.
    • (2010) Blood , vol.116 , Issue.22 , pp. 4631-4638
    • Kanezaki, R.1    Toki, T.2    Terui, K.3
  • 14
    • 0023651307 scopus 로고
    • Rna splice junctions of different classes of eukaryotes: Sequence statistics and functional implications in gene expression
    • Shapiro MB, Senapathy P. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res. 1987;15(17): 7155-7174.
    • (1987) Nucleic Acids Res. , vol.15 , Issue.17 , pp. 7155-7174
    • Shapiro, M.B.1    Senapathy, P.2
  • 15
    • 0030926006 scopus 로고    scopus 로고
    • A lineage-selective knockout establishes the critical role of transcription factor gata-1 in megakaryocyte growth and platelet development
    • Shivdasani RA, Fujiwara Y, McDevitt MA, Orkin SH. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J. 1997;16(13):3965-3973.
    • (1997) EMBO J. , vol.16 , Issue.13 , pp. 3965-3973
    • Shivdasani, R.A.1    Fujiwara, Y.2    McDevitt, M.A.3    Orkin, S.H.4
  • 16
    • 58249108548 scopus 로고    scopus 로고
    • The key role of stem cell factor/kit signaling in the proliferation of blast cells from down syndrome-related leukemia
    • Toki T, Kanezaki R, Adachi S, et al. The key role of stem cell factor/KIT signaling in the proliferation of blast cells from Down syndrome-related leukemia. Leukemia. 2009;23(1):95-103.
    • (2009) Leukemia , vol.23 , Issue.1 , pp. 95-103
    • Toki, T.1    Kanezaki, R.2    Adachi, S.3
  • 17
    • 67649981723 scopus 로고    scopus 로고
    • Direct binding of prb/e2f-2 to gata-1 regulates maturation and terminal cell division during erythropoiesis
    • Kadri Z, Shimizu R, Ohneda O, et al. Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis. PLoS Biol. 2009;7(6):e1000123.
    • (2009) Plos Biol , vol.7 , Issue.6
    • Kadri, Z.1    Shimizu, R.2    Ohneda, O.3
  • 18
    • 77955870488 scopus 로고    scopus 로고
    • Developmental stage-specific interplay of gata1 and igf signaling in fetal megakaryopoiesis and leukemogenesis
    • Klusmann JH, Godinho FJ, Heitmann K, et al. Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis. Genes Dev. 2010;24(15): 1659-1672.
    • (2010) Genes Dev , vol.24 , Issue.15 , pp. 1659-1672
    • Klusmann, J.H.1    Godinho, F.J.2    Heitmann, K.3
  • 19
    • 1642535431 scopus 로고    scopus 로고
    • Akt activity determines sensitivity to mammalian target of rapamycin (mtor) inhibitors by regulating cyclin d1 and c-myc expression
    • Gera JF, Mellinghoff IK, Shi Y, et al. AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression. J Biol Chem. 2004; 279(4):2737-2746.
    • (2004) J Biol Chem , vol.279 , Issue.4 , pp. 2737-2746
    • Gera, J.F.1    Mellinghoff, I.K.2    Shi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.