Epithelial healing and visual outcomes of patients using omega-3 oral nutritional supplements before and after photorefractive keratectomy: A pilot study

Cornea

Volumn 32, Issue 6, 2013, Pages 761-765

  Ong, Nikki Heidi ^a   Purcell, Tracy L ^a   Roch Levecq, Anne Catherine ^a   Wang, Dorothy ^a   Isidro, Marichelle A ^a   Bottos, Katia M ^a   Heichel, Christopher W ^a   Schanzlin, David J ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Cornea; Fatty acids; Omega 3; PRK; Tear breakup time

Indexed keywords

FLUORESCEIN; OMEGA 3 FATTY ACID;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; EPITHELIZATION; FEMALE; HUMAN; MALE; OUTCOME ASSESSMENT; PHOTOGRAPHY; PHOTOREFRACTIVE KERATECTOMY; PILOT STUDY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; REFRACTION ERROR; SINGLE BLIND PROCEDURE; SKIN DEFECT; VISUAL ACUITY;

ADMINISTRATION, ORAL; ADULT; DIETARY SUPPLEMENTS; EPITHELIUM, CORNEAL; FATTY ACIDS, OMEGA-3; FEMALE; HUMANS; MALE; MYOPIA; PHOTOREFRACTIVE KERATECTOMY; PILOT PROJECTS; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PROSPECTIVE STUDIES; SINGLE-BLIND METHOD; TEARS; TREATMENT OUTCOME; VISUAL ACUITY; WOUND HEALING;

EID: 84879190368     PISSN: 02773740     EISSN: 15364798     Source Type: Journal    
DOI: 10.1097/ICO.0b013e31826905b3     Document Type: Article

References (17)

1. Wilson SE. Everett Kinsey Lecture. Keratocyte apoptosis in refractive surgery. CLAO J. 1998;24:181-185.
2. Netto MV, Mohan RR, Ambrósio R Jr, et al. Wound healing in the cornea: a review of refractive surgery complications and new prospects for therapy. Cornea. 2005;24:509-522.
3. Ramirez-Florez S, Maurice DM. Inflammatory cells, refractive regression, and haze after excimer laser PRK. J Refract Surg. 1996;12: 370-381.
4. McDonald MB. Role of anti-inflammatory medication: PRK. Loteprednol Etabonate Technical Paper. Part 1: Refractive. 2009;October:1-4.
5. Maroon JC, Bost JW, Borden MK, et al. Natural antiinflammatory agents for pain relief in athletes. Neurosurg Focus. 2006;21:4.
6. Gilbard JP. Dry eye. Natural history, diagnosis and treatment. Available at: http://www.dryeyeinfo.org. Accessed June 1 2004.
7. Brignole-Baudouin F, Baudouin C, Aragona P, et al. A multicentre, double-masked, randomized, controlled trial assessing the effect of oral supplementation of omega-3 and omega-6 fatty acids on a conjunctival inflammatory marker in dry eye patients. Acta Ophthalmol. 2011;89: e591-e597.
8. Wojtowicz JC, Butovich I, Uchiyama E, et al. Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye. Cornea. 2011;30:308-314.
9. Torres LF, Sancho C, Tan B, et al. Early postoperative pain following Epi-LASIK and photorefractive keratectomy: a prospective, comparative, bilateral study. J Refract Surg. 2007;23:126-132.
10. Tan BU, Purcell TL, Nalgirkar A, et al. Photorefractive keratectomy for the correction of residual refractive error with Intacs intrastromal corneal ring segments in place. J Cataract Refract Surg. 2008;34:909-915.
11. Lichtinger A, Purcell TL, Schanzlin DJ, et al. Gabapentin for postoperative pain after photorefractive keratectomy: a prospective, randomized, double-blind, placebo-controlled trial. J Refract Surg. 2011;27:613-617.
12. Saad HA, Terry MA, Shamie N, et al. An easy and inexpensive method for quantitative analysis of endothelial damage by using vital dye staining and Adobe Photoshop software. Cornea. 2008;27:818-824.
13. Statistica for Windows [computer program]. Version 9.1, Tulsa, OK: Statsoft; 2009.
14. Srinivasan BD. Corneal reepithelialization and anti-inflammatory agents. Trans Am Ophthalmol Soc. 1982;80:758-822.
15. Matt C. Fish oil benefits and side effects from answer fitness. Available at: http://www.answerfitness.com/139/fish-oil-supplements-benefits-sideeffects- answer-fitness/. Accessed September 7, 2012.
16. Macsai MS. The role of omega-3 dietary supplementation in blepharitis and meibomian gland dysfunction (an AOS thesis). Trans Am Ophthalmol Soc. 2008;106:336-356.
17. Foster CS. Dry eye syndrome, eMedicine ophthalmology. Available at: htt://emedicine.medscape.com. Accessed February 15, 2011.