-
1
-
-
0032511583
-
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group
-
UK Prospective Diabetes Study Group
-
UK Prospective Diabetes Study Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet. 1998;352:837-853.
-
(1998)
Lancet
, vol.352
, pp. 837-853
-
-
-
2
-
-
0029886690
-
Intensive insulin therapy in type II diabetes: Rationale and collaborative clinical trial results
-
Colwell JA. Intensive insulin therapy in type II diabetes: rationale and collaborative clinical trial results. Diabetes. 1996;45(Suppl 3): S87-S90.
-
(1996)
Diabetes
, vol.45
, Issue.SUPPL. 3
-
-
Colwell, J.A.1
-
3
-
-
0029083477
-
Lessons from UK prospective diabetes study
-
Turner RC, Holman RR. Lessons from UK prospective diabetes study. Diabetes Res Clin Pract. 1995;28(Suppl):S151-S157.
-
(1995)
Diabetes Res Clin Pract
, vol.28
, Issue.SUPPL.
-
-
Turner, R.C.1
Holman, R.R.2
-
4
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
-
Diabetes Control and Complications Trial Research Group
-
Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329:977-986.
-
(1993)
N Engl J Med
, vol.329
, pp. 977-986
-
-
-
5
-
-
12844276465
-
Comparison of basal insulin added to oral agents versus twice-daily premixed insulin as initial insulin therapy for type 2 diabetes
-
Janka HU, Plewe G, Riddle MC, Kliebe-Frisch C, Schweitzer MA, Yki-Jarvinen H. Comparison of basal insulin added to oral agents versus twice-daily premixed insulin as initial insulin therapy for type 2 diabetes. Diabetes Care. 2005;28:254-259.
-
(2005)
Diabetes Care
, vol.28
, pp. 254-259
-
-
Janka, H.U.1
Plewe, G.2
Riddle, M.C.3
Kliebe-Frisch, C.4
Schweitzer, M.A.5
Yki-Jarvinen, H.6
-
6
-
-
82655169421
-
Intensifying treatment of type 2 diabetes mellitus: Adding insulin
-
Peters KR. Intensifying treatment of type 2 diabetes mellitus: adding insulin. Pharmacotherapy. 2011;31:54S-64S.
-
(2011)
Pharmacotherapy
, vol.31
-
-
Peters, K.R.1
-
7
-
-
38749103090
-
Why insulin sensitizers but not secretagogues should be retained when initiating insulin in type 2 diabetes
-
Raskin P. Why insulin sensitizers but not secretagogues should be retained when initiating insulin in type 2 diabetes. Diabetes Metab Res Rev. 2008;24:3-13.
-
(2008)
Diabetes Metab Res Rev
, vol.24
, pp. 3-13
-
-
Raskin, P.1
-
8
-
-
0034819464
-
Combination therapies with insulin in type 2 diabetes
-
Yki-Jarvinen H. Combination therapies with insulin in type 2 diabetes. Diabetes Care. 2001;24:758-767.
-
(2001)
Diabetes Care
, vol.24
, pp. 758-767
-
-
Yki-Jarvinen, H.1
-
9
-
-
77956149675
-
Continuation versus discontinuation of insulin secretagogues when initiating insulin in type 2 diabetes
-
Swinnen SG, Dain M P, Mauricio D, Devries JH, Hoekstra JB, Holleman F. Continuation versus discontinuation of insulin secretagogues when initiating insulin in type 2 diabetes. Diabetes Obes Metab. 2010;12: 923-925.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 923-925
-
-
Swinnen, S.G.1
Dain, M.P.2
Mauricio, D.3
Devries, J.H.4
Hoekstra, J.B.5
Holleman, F.6
-
10
-
-
34347393269
-
Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus
-
He YL, Serra D, Wang Y et al. Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus. Clin Pharmacokinet. 2007;46:577-588.
-
(2007)
Clin Pharmacokinet
, vol.46
, pp. 577-588
-
-
He, Y.L.1
Serra, D.2
Wang, Y.3
-
11
-
-
38149096290
-
Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance
-
Rosenstock J, Foley JE, Rendell M, et al. Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance. Diabetes Care. 2008;31:30-35.
-
(2008)
Diabetes Care
, vol.31
, pp. 30-35
-
-
Rosenstock, J.1
Foley, J.E.2
Rendell, M.3
-
12
-
-
79960831855
-
Mechanisms of Action of the DPP-4 Inhibitor Vildagliptin in Man
-
Ahren B, Schweizer A, Dejager S, Villhauer EB, Dunning BE, Foley JE. Mechanisms of Action of the DPP-4 Inhibitor Vildagliptin in Man. Diabetes Obes Metab. 2011;13:775-783.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 775-783
-
-
Ahren, B.1
Schweizer, A.2
Dejager, S.3
Villhauer, E.B.4
Dunning, B.E.5
Foley, J.E.6
-
13
-
-
33646569958
-
Contributions of fasting and postprandial glucose to hemoglobin A1c
-
Monnier L, Colette C. Contributions of fasting and postprandial glucose to hemoglobin A1c. Endocr Pract. 2006;12(Suppl 1):42-46.
-
(2006)
Endocr Pract
, vol.12
, Issue.SUPPL. 1
, pp. 42-46
-
-
Monnier, L.1
Colette, C.2
-
15
-
-
80052822199
-
Emerging role of insulin with incretin therapies for management of type 2 diabetes
-
Ahluwalia R, Vora J. Emerging role of insulin with incretin therapies for management of type 2 diabetes. Diabetes Ther. 2011;2:146-161.
-
(2011)
Diabetes Ther
, vol.2
, pp. 146-161
-
-
Ahluwalia, R.1
Vora, J.2
-
16
-
-
84882238199
-
Combination Therapies of DPP4 Inhibitors and GLP1 Analogues with Insulin in Type 2 Diabetic Patients: A Systematic Review
-
Epub 2012 Jun 22
-
Rizos EC, Ntzani EE, Papanas N, et al. Combination Therapies of DPP4 Inhibitors and GLP1 Analogues with Insulin in Type 2 Diabetic Patients: A Systematic Review. Curr Vasc Pharmacol. Epub 2012 Jun 22.
-
Curr Vasc Pharmacol
-
-
Rizos, E.C.1
Ntzani, E.E.2
Papanas, N.3
-
17
-
-
84863950025
-
Impact of insulin resistance, body mass index, disease duration, and duration of metformin use on the efficacy of vildagliptin
-
Schweizer A, Dejager S, Foley JE. Impact of insulin resistance, body mass index, disease duration, and duration of metformin use on the efficacy of vildagliptin. Diabetes Ther. 2012;3:8.
-
(2012)
Diabetes Ther
, vol.3
, pp. 8
-
-
Schweizer, A.1
Dejager, S.2
Foley, J.E.3
-
18
-
-
0036020278
-
Hypoglycaemia: The limiting factor in the glycaemic management of Type I and Type II diabetes
-
Cryer PE. Hypoglycaemia: the limiting factor in the glycaemic management of Type I and Type II diabetes. Diabetologia. 2002;45: 937-948.
-
(2002)
Diabetologia
, vol.45
, pp. 937-948
-
-
Cryer, P.E.1
-
19
-
-
82255185915
-
Glucose-dependent insulinotropic polypeptide: A bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans
-
Christensen M, Vedtofte L, Holst JJ, Vilsboll T, Knop FK. Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans. Diabetes. 2011;60:3103-3109.
-
(2011)
Diabetes
, vol.60
, pp. 3103-3109
-
-
Christensen, M.1
Vedtofte, L.2
Holst, J.J.3
Vilsboll, T.4
Knop, F.K.5
-
20
-
-
34247874561
-
Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes
-
Fonseca V, Schweizer A, Albrecht D, Baron MA, Chang I, Dejager S. Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes. Diabetologia. 2007;50:1148-1155.
-
(2007)
Diabetologia
, vol.50
, pp. 1148-1155
-
-
Fonseca, V.1
Schweizer, A.2
Albrecht, D.3
Baron, M.A.4
Chang, I.5
Dejager, S.6
-
21
-
-
47049084841
-
Sustained efficacy and reduced hypoglycemia during one year of treatment with vildagliptin added to insulin in patients with type 2 diabetes mellitus
-
Fonseca V, Baron M, Shao Q, Dejager S. Sustained efficacy and reduced hypoglycemia during one year of treatment with vildagliptin added to insulin in patients with type 2 diabetes mellitus. Horm Metab Res. 2008;40:427-430.
-
(2008)
Horm Metab Res
, vol.40
, pp. 427-430
-
-
Fonseca, V.1
Baron, M.2
Shao, Q.3
Dejager, S.4
-
22
-
-
84873873967
-
Improved glycaemic control with vildagliptin added to insulin, with or without metformin, in patients with type 2 diabetes mellitus
-
Kothny W, Foley J, Kozlovski P, Shao Q, Gallwitz B, Lukashevich V. Improved glycaemic control with vildagliptin added to insulin, with or without metformin, in patients with type 2 diabetes mellitus. Diabetes Obes Metab. 2013;15:252-257.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 252-257
-
-
Kothny, W.1
Foley, J.2
Kozlovski, P.3
Shao, Q.4
Gallwitz, B.5
Lukashevich, V.6
-
23
-
-
80052551137
-
Safety and efficacy of vildagliptin versus placebo in patients with type 2 diabetes and moderate or severe renal impairment: A prospective 24-week randomized placebo-controlled trial
-
Lukashevich V, Schweizer A, Shao Q, Groop PH, Kothny W. Safety and efficacy of vildagliptin versus placebo in patients with type 2 diabetes and moderate or severe renal impairment: a prospective 24-week randomized placebo-controlled trial. Diabetes Obes Metab. 2011;13:947-954.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 947-954
-
-
Lukashevich, V.1
Schweizer, A.2
Shao, Q.3
Groop, P.H.4
Kothny, W.5
-
24
-
-
84873848407
-
Efficacy of vildagliptin in combination with insulin in patients with type 2 diabetes and severe renal impairment
-
Lukashevich V, Schweizer A, Foley JE, Dickinson S, Groop PH, Kothny W. Efficacy of vildagliptin in combination with insulin in patients with type 2 diabetes and severe renal impairment. Vasc Health Risk Manag. 2013;9:21-28.
-
(2013)
Vasc Health Risk Manag
, vol.9
, pp. 21-28
-
-
Lukashevich, V.1
Schweizer, A.2
Foley, J.E.3
Dickinson, S.4
Groop, P.H.5
Kothny, W.6
-
25
-
-
77953192546
-
An assessment of adverse effects of vildagliptin versus comparators on the liver, the pancreas, the immune system, the skin and in patients with impaired renal function from a large pooled database of Phase II and III clinical trials
-
Ligueros-Saylan M, Foley JE, Schweizer A, Couturier A, Kothny W. An assessment of adverse effects of vildagliptin versus comparators on the liver, the pancreas, the immune system, the skin and in patients with impaired renal function from a large pooled database of Phase II and III clinical trials. Diabetes Obes Metab. 2010;12:495-509.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 495-509
-
-
Ligueros-Saylan, M.1
Foley, J.E.2
Schweizer, A.3
Couturier, A.4
Kothny, W.5
-
26
-
-
79951607030
-
Assessing the general safety and tolerability of vildagliptin: Value of pooled analyses from a large safety database versus evaluation of individual studies
-
Schweizer A, Dejager S, Foley JE, Kothny W. Assessing the general safety and tolerability of vildagliptin: value of pooled analyses from a large safety database versus evaluation of individual studies. Vasc Health Risk Manag. 2011;7:49-57.
-
(2011)
Vasc Health Risk Manag
, vol.7
, pp. 49-57
-
-
Schweizer, A.1
Dejager, S.2
Foley, J.E.3
Kothny, W.4
-
27
-
-
84969302615
-
Evaluation of vildagliptin and fxed dose combination of vildagliptin and metformin on glycemic control and insulin dose over 3 months in patients with type 2 diabetes mellitus
-
Ved P, Shah S. Evaluation of vildagliptin and fxed dose combination of vildagliptin and metformin on glycemic control and insulin dose over 3 months in patients with type 2 diabetes mellitus. Indian J Endocrinol Metab. 2012;16(Suppl 1):S110-S113.
-
(2012)
Indian J Endocrinol Metab
, vol.16
, Issue.SUPPL. 1
-
-
Ved, P.1
Shah, S.2
-
28
-
-
33845513982
-
Interactions between delivery, transport, and phosphorylation of glucose in governing uptake into human skeletal muscle
-
Bertoldo A, Pencek RR, Azuma K, et al. Interactions between delivery, transport, and phosphorylation of glucose in governing uptake into human skeletal muscle. Diabetes. 2006;55:3028-3037.
-
(2006)
Diabetes
, vol.55
, pp. 3028-3037
-
-
Bertoldo, A.1
Pencek, R.R.2
Azuma, K.3
-
29
-
-
33744920053
-
Dose-responsive insulin regulation of glucose transport in human skeletal muscle
-
Pencek RR, Bertoldo A, Price J, Kelley C, Cobelli C, Kelley DE. Dose-responsive insulin regulation of glucose transport in human skeletal muscle. Am J Physiol Endocrinol Metab. 2006;290:E1124-E1130.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Pencek, R.R.1
Bertoldo, A.2
Price, J.3
Kelley, C.4
Cobelli, C.5
Kelley, D.E.6
-
30
-
-
64749110344
-
Hypoglycemia: Still the limiting factor in the glycemic management of diabetes
-
Cryer PE. Hypoglycemia: still the limiting factor in the glycemic management of diabetes. Endocr Pract. 2008;14:750-756.
-
(2008)
Endocr Pract
, vol.14
, pp. 750-756
-
-
Cryer, P.E.1
-
31
-
-
57249098943
-
The barrier of hypoglycemia in diabetes
-
Cryer PE. The barrier of hypoglycemia in diabetes. Diabetes. 2008;57:3169-3176.
-
(2008)
Diabetes
, vol.57
, pp. 3169-3176
-
-
Cryer, P.E.1
-
32
-
-
0141446274
-
Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans
-
Ahren B, Holst JJ, Mari A. Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans. Diabetes Care. 2003;26: 2860-2864.
-
(2003)
Diabetes Care
, vol.26
, pp. 2860-2864
-
-
Ahren, B.1
Holst, J.J.2
Mari, A.3
-
33
-
-
79961191559
-
Regulation of glucagon secretion by incretins
-
Holst JJ, Christensen M, Lund A, et al. Regulation of glucagon secretion by incretins. Diabetes Obes Metab. 2011;13(Suppl 1):89-94.
-
(2011)
Diabetes Obes Metab
, vol.13
, Issue.SUPPL. 1
, pp. 89-94
-
-
Holst, J.J.1
Christensen, M.2
Lund, A.3
-
34
-
-
65249095686
-
Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes
-
Ahren B, Schweizer A, Dejager S, et al. Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes. J Clin Endocrinol Metab. 2009;94:1236-1243.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 1236-1243
-
-
Ahren, B.1
Schweizer, A.2
Dejager, S.3
-
35
-
-
54049099230
-
Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes
-
Foley JE, Ligueros-Saylan M, He YL, et al. Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes. Horm Metab Res. 2008;40:727-730.
-
(2008)
Horm Metab Res
, vol.40
, pp. 727-730
-
-
Foley, J.E.1
Ligueros-Saylan, M.2
He, Y.L.3
-
36
-
-
84873814444
-
-
Konigswinter, Germany: infll Kommunikation GmbH
-
Ferrannini E, Groop PH, Nauck M, Fioretto P, Hach T, Thomas M. The Signifcance of the Kidney in Diabetes. Konigswinter, Germany: infll Kommunikation GmbH; 2012.
-
(2012)
The Signifcance of the Kidney In Diabetes
-
-
Ferrannini, E.1
Groop, P.H.2
Nauck, M.3
Fioretto, P.4
Hach, T.5
Thomas, M.6
-
37
-
-
84864285795
-
Management of hyperglycaemia in type 2 diabetes: A patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
-
Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia. 2012;55:1577-1596.
-
(2012)
Diabetologia
, vol.55
, pp. 1577-1596
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
|