Effects of Glucose Availability on Expression of the Key Genes Involved in Synthesis of Milk Fat, Lactose and Glucose Metabolism in Bovine Mammary Epithelial Cells

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Liu, Hongyun ^a   Zhao, Ke ^a   Liu, Jianxin ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ALPHA LACTALBUMIN; BETA 1, 4 GALACTOSYLTRANSFERASE; FATTY ACID SYNTHASE; GALACTOSYLTRANSFERASE; GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; LACTOSE; MESSENGER RNA; MILK FAT; PENTOSE PHOSPHATE; PYRUVATE KINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOENERGY; BREAST EPITHELIUM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SYNTHESIS; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GLUCOSE METABOLISM; GLYCOLYSIS; IN VITRO STUDY; LIPOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE;

ACETYL-COA CARBOXYLASE; ANIMALS; BIOSYNTHETIC PATHWAYS; CATTLE; CELLS, CULTURED; DIACYLGLYCEROL O-ACYLTRANSFERASE; EPITHELIAL CELLS; FATTY ACID SYNTHASE, TYPE I; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSEPHOSPHATE DEHYDROGENASE; GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE; LACTOSE; LACTOSE SYNTHASE; LIPID METABOLISM; MAMMARY GLANDS, ANIMAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MILK; PYRUVATE KINASE; RNA, MESSENGER;

BOVINAE;

EID: 84879165580     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066092     Document Type: Article

References (36)

1. Bell AW, Bauman DE, (1997) Adaptations of glucose metabolism during pregnancy and lactation. J Mammary Gland Biol Neoplasia 2: 265-278.
2. Annison EF, Linzell JL, (1964) The oxidation and utilization of glucose and acetate by the mammary gland of the goat in relation to their over-all metabolism and to milk formation. J Physiol 175: 372-385.
3. Hurtaud C, Lemosquet S, Rulquin H, (2000) Effect of graded duodenal infusions of glucose on yield and composition of milk from dairy cows. 2. Diets based on grass silage. J Dairy Sci 83: 2952-2962.
4. Rulquin H, Rigout S, Lemosquet S, Bach A, (2004) Infusion of glucose directs circulating amino acids to the mammary gland in well-fed dairy cows. J Dairy Sci 87: 340-349.
5. Rigout S, Lemosquet S, Van Eys JE, Blum JW, Rulquin H, (2002) Duodenal glucose increases glucose fluxes and lactose synthesis in grass silage-fed dairy cows. J Dairy Sci 85: 595-606.
6. Lemosquet S, Rideau N, Rulquin H, Faverdin P, Simon J, et al. (1997) Effects of a duodenal glucose infusion on the relationship between plasma concentrations of glucose and insulin in dairy cows. J Dairy Sci 80: 2854-2865.
7. Al-Trad B, Reisberg K, Wittek T, Penner GB, Alkaassem A, et al. (2009) Increasing intravenous infusions of glucose improve body condition but not lactation performance in midlactation dairy cows. J Dairy Sci 92: 5645-5658.
8. Oldick BS, Staples CR, Thatcher WW, (1997) Abomasal infusion of glucose and fat-effect on digestion, production, and ovarian and uterine functions of cows. J Dairy Sci 80: 1315-1328.
9. Judson GJ, Leng RA, (1973) Studies on the control of gluconeogenesis in sheep: effect of glucose infusion. Brit J Nutr 29: 175-195.
10. Xiao CT, Cant JP, (2005) Relationship between glucose transport and metabolism in isolated bovine mammary epithelial cells. J Dairy Sci 88: 2794-2805.
11. Zhao K, Liu HY, Wang HF, Zhou MM, Liu JX, (2012) Effect of glucose availability on glucose transport in bovine mammary epithelial cells. Animal 6: 488-493.
12. Zhao K, Liu H, Zhou M, Liu J, (2010) Establishment and characterization of a lactating bovine mammary epithelial cell model for the study of milk synthesis. Cell Biol Int 34: 717-721.
13. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 25: 402-408.
14. Kimmich GA, Randles J, Brand JS, (1975) Assay of picomole amounts of ATP, ADP, and AMP using the luciferase enzyme system. Anal Biochem 69: 187-206.
15. Harvatine KJ, Boisclair YR, Bauman DE, (2009) Recent advances in the regulation of milk fat synthesis. Animal 3: 40-54.
16. Vaulont S, Vasseur-Cognet M, Kahn A, (2000) Glucose regulation of gene transcription. J Biol Chem 275: 31555-315558.
17. Bionaz M, Loor JJ, (2008) Gene networks driving bovine milk fat synthesis during the lactation cycle. BMC Genomics 9: 366-387.
18. Bernard L, Leroux C, Chilliard Y, (2008) Expression and nutritional regulation of lipogenic genes in the reminant lactating mammary gland. Adv Exp Med Biol 606: 67-108.
19. Towle HC, Kaytor EN, Shih HM, (1997) Regulation of the expression of lipogenic enzyme genes by carbohydrate. Annu Rev Nutr 17: 405-433.
20. Edwards PA, Tabor D, Kast HR, Venkateswaran A, (2000) Regulation of gene expression by SREBP and SCAP. Bioch et Bioph Acta 1529: 103-113.
21. Bauman DE, Perfield JW, Harvatine KJ, Baumgard LH, (2008) Regulation of fat synthesis by conjugated linoleic acid: lactation and the ruminant model. J Nutr 138: 403-409.
22. Hammerman PS, Fox CCJ, Thompson CB, (2004) Beginnings of a signal-transduction pathway for bioenergetic control of cell survival. Trends Biochem Sci 29: 586-592.
23. Hurtaud C, Rulquin H, Verite R, (1998) Effect of graded duodenal infusions of glucose on yield and composition of milk from dairy cows. 1. Diets based on corn silage. J Dairy Sci 81: 3239-3247.
24. Girard J, Ferré P, Foufelle F, (1997) Mechanisms by which carbohydrates regulate expression on genes for glycolytic and lipogenic enzymes. Annu Rev Nutr 17: 325-352.
25. Farrell Jr HM, Jimenez-Flores R, Bleck GT, Brown EM, Butler JE, et al. (2004) Nomenclature of the proteins of cows' milk-sixth revision. J Dairy Sci 87: 1641-1674.
26. Ramakrishnan B, Qasba PK, (2001) Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the β 1, 4-galactosyltransferase-I. J Mol Biol 310: 205-218.
27. Mellenberger RW, Bauman DE, (1974) Lactose synthesis in rabbit mammary tissue during pregnancy and lactation. Biochem J 142: 659-665.
28. Lemosquet S, Rigout S, Bach A, Rulquin H, Blum JW, (2004) Glucose metabolism in lactating cows in response to isoenergetic infusions of propionic acid or duodenal glucose. J Dairy Sci 87: 1767-1777.
29. Kleiber M, Black AL, Brown MA, Baxter CF, Luick JR, et al. (1955) Glucose as a precursor of milk constituents in the intact dairy cow. Bioch et Bioph Acta 17: 252-260.
30. Abraham S, Hirsch PF, Chaikoff IL, (1954) The quantitiative significance of glycolysis and non-glycolysis in glucose utilization by rat mammary gland. J Biol Chem 211: 31-38.
31. Renner ED, Plagemann PGW, Bernlohr RW, (1972) Permeation of glucose by simple and facilitated diffusion by Novikoff rat hepatoma cells in suspension culture and its relationship to glucose metabolism. J Biol Chem 247: 5765.-5776.
32. Möbius K, Arias-Cartin R, Breckau D, Hännig A, Riedmann K, et al. (2010) Heme biosynthesis is coupled to electron transport chains for energy generation. Proc Natl Acad Sci USA 107: 10436-10441.
33. Rathmell JC, Heiden MGV, Harris MH, Frauwirth KA, Thompson CB, (2000) In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. Mol Cell 6: 683-692.
34. Humphrey BD, Rudrappa SG, (2008) Increased glucose availability activates chicken thymocyte metabolism and survival. J Nutr 138: 1153-1157.
35. Han L, Ma Q, Li J, Liu H, Li W, et al. (2011) High glucose promotes pancreatic cancer cell proliferation via the induction of EGF expression and transactivation of EGFR. PLoS One 6(11): e27074.
36. Kahn CM (2005) Merck veterinary manual. 9th Ed. Merck & Co., Inc., Whitehouse Station, N.J. 2586 P.