Moringa oleifera leaf extract prevents in vitro oxidative DNA damage

Asian Journal of Pharmaceutical and Clinical Research

Volumn 6, Issue SUPPL. 2, 2013, Pages 157-161

  Sikder, Kunal ^a   Sinha, Mahuya ^a   Das, Nilanjan ^a   Das, Dipesh K R ^a   Datta, Sanjukta ^a   Dey, Sanjit ^a  

^a UNIVERSITY OF CALCUTTA   (India)

Author keywords

Antioxidants; DNA damage; Free radicals; Moringa oleifera; Polyphenols

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; DNA; DNA TOPOISOMERASE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MORINGA OLEIFERA EXTRACT; POLYPHENOL;

ANALYTIC METHOD; ANTIOXIDANT ACTIVITY; ARTICLE; COMET ASSAY; CONCENTRATION RESPONSE; DNA DAMAGE; DNA DENATURATION; DNA METABOLISM; DRUG USE; ENZYME INHIBITION; FENTON REACTION; FERRIC REDUCING ANTIOXIDANT POWER ASSAY; FLUORESCENCE MICROSCOPY; GEL ELECTROPHORESIS; IN VITRO STUDY; LIPID PEROXIDATION; LYMPHOCYTE; MEMBRANE DAMAGE; OXIDATIVE STRESS; PHYTOCHEMISTRY; PLANT LEAF; PROTECTION;

EID: 84879161453     PISSN: 09742441     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Maluf SW. Monitoring DNA damage following radiation exposure using cytokinesis-block micronucleus method and alkaline single-cell gel electrophoresis. Clin Chim Acta. 2004;347: 15-24.
2. Kamat J P, Boloor K K, Devasagayam T P A, Venkatachalam S R. Antioxidant properties of Asparagus racemosus against damage induced by gamma-radiation in rat liver mitochondria. J Ethnopharmacol. 2000;71: 425-435.
3. Rice-Evans CA, Miller NJ, Panganga G. Antioxidant Properties of Phenolic Compounds. Trends in Plant Sci. 1996;2: 152-159.
4. Wangensteen H, Samuelsen AB, Malterud KE. Antioxidant activity in extracts from coriander. Food Chem. 2004;88: 293-297.
5. Hong Y, Lin S, Jiang Y, Ashraf M. Variation in contents of total phenolics and flavonoids and antioxidant activities in the leaves of 11 Eriobotrya species. Plant food Hum Nutr. 2008;63: 200-204.
6. Saito K, Kohno M, Yoshizaki F, Niwano Y. Extensive screening for edible herbal extracts with potent scavenging activity against superoxide anions. Plant Foods Hum Nutr. 2008;63: 65-70.
7. Nhukarume L, Chikwambi Z, Muchuweti M, Chipurura B. Phenolic content and antioxidant capacities of Parinari curatelifolia, Strychnos spinosa and Adansonia digitata. J Food Biochem. 2010;34: 207-221.
8. Somali MA, Bajnedi MA, Al-Faimani SS. Chemical composition and characteristics of Moringa peregrina seeds and seed oil. J Am Oil Chem Soc. 1984;61: 85-86.
9. Morton JF. The horseradish tree, Moringa pterigosperma (Moringaceae). A boon to arid lands. Econ Bot. 1991; 45: 318-333.
10. Sreelatha S, Padma PR. Antioxidant Activity and Total Phenolic Content of Moringa oleifera Leaves in Two Stages of Maturity. Plant Foods Hum Nutr. 2009;64: 303-311.
11. Anwar F, Latif S, Ashraf M, Gilani AH. Moringa oleifera: a food plant with multiple medicinal uses. Phytother Res. 2007; 21: 17-25.
12. Rao VA, Devi PU, Kamath R. In vivo radioprotective effect of Moringa oleifera leaves. Indian J Exp Biol. 2001;39: 858-863.
13. Tsimogiannis DI, Oreopoulou V. The contribution of flavonoid C-ring on the DPPH free radical scavenging efficiency. A kinetic approach for the 3', 4'-hydroxyl substituted members. Innovative food sci emerg technol. 2006;7: 140-146.
14. Sinha M, Das DK, Datta S, Ghosh S, Dey S. Amelioration of ionizing radiation induced lipid peroxidation in mouse liver by Moringa oleifera Lam. leaf extract. Indian J Exp Biol. 2012;50: 209-215.
15. Sinha M, Das DK, Bhattacharjee S, Majumdar S, Dey S. Leaf extract of Moringa oleifera prevents ionizing radiation-induced oxidative stress in mice. J Med Food. 2011;14: 1167-1172.
16. Das N, Sikder K, Ghosh S, Fromenty B, Dey S. Moringa oleifera Lam. Leaf extract prevents early liver injury and restores antioxidant status in mice fed with high-fat diet. Indian J Exp Biol. 2012;50: 404-412.
17. Babu V, Gangadevi T, Subramoniam A. Antidiabetic activity of ethanol extract of Cassia kleinii leaf in streptozotocin induced diabetic rats and isolation of an active fraction and toxicity evaluation of the extract. Indian J Pharmacol. 2003;35: 290-296.
18. Taga MS, Miller EE, Pratt DE. Chia seeds as a source of natural lipid antioxidants. J Am Oil Chem Soc. 1984;61: 928-931.
19. Oktay M, Gulcin I, Kufrevioglu OI. Determination of in vitro antioxidant activity fennel seed extracts. Lebensmittel-Wissenschaft Technol. 2003;36: 263-271.
20. Decker EA, Welch B. Role of ferritin as a lipid oxidation catalyst in muscle food. J Agric Food Chem. 1990;38: 674-677.
21. Benzie IFF, Strain JJ. Ferric Reducing Ability of Plasma as a measure of antioxidant power, The FRAP assay. Anal Biochem. 1996;239: 70-76.
22. Oyaizu M. Studies on product of browning reaction prepared from glucose amine Japanese J Nutr. 1986;44: 307-315.
23. Murthy CKN, Singh RP, Jayaprakasha GK. Antioxidant activities of grape pomace extracts. J Agric Food Chem. 2002;50: 5905-5914.
24. Takao T, Kitatani F, Watanabe N, Yagi A, Sakata KA. Simple screening method for antioxidants and isolation of several antioxidant produced by marine bacteria from fish and shellfish. Biosci Biotechnol Biochem. 1994;58: 1780-1783.
25. Henle SE, Luo Y, Linn S. Fe2+, Fe3+, and Oxygen React with DNA-Derived Radicals Formed during Iron-Mediated Fenton Reactions. Biochem J. 1996;35: 12212-12219.
26. Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res. 1988;175-184.
27. Roy A, Das BB, Ganguly A, BoseDasgupta S, Khalkho VN, Pal C, Dey S, Giri SV, Jaisankar P, Dey S, Majumder KH. An insight into the mechanism of inhibition of unusual bi-subunit topoisomerase I from Leishmania donovani by 3, 3'-di-indolylmethane, a novel DNA topoisomerase I poison with a strong binding affinity to the enzyme. Biochem J. 2008;409: 611-622.
28. Gordon MH. The mechanism of antioxidant action in vitro. Food antiox. 1990;1-18.
29. O'Byme DJ, Devaraj S, Grundy SM, Jialal I. Comparison of antioxidant effects of Concord grape juice flavonoids and α-tocopherol on markers of oxidative stress in healthy adults. Am J Clin Nutr. 2002;76: 1367-1374.
30. Spencer JPE. DNA damage in human respiratory tract epithelial cells. FEBS Lett. 1995;375: 179-182.
31. Padmarao P, Acharya BM, Dennis TJ. Pharmacognostic study on stembark of Moringa oleifera Lam. Bull. Medico-Ethno-Botanical Res. 1996;17: 141-151.
32. Liu LF. DNA topoisomerase poisons as antitumor drugs. Annu Rev Biochem. 1989;58: 351-375.
33. Wang JC. DNA topoisomerases. Annu Rev Biochem. 1996;65: 635-692.
34. Champoux JJ. DNA topoisomerases: structure, function and mechanism. Annu Rev Biochem. 2001;70: 369-413.
35. Chitra K, Pillai KS. Antioxidants in health. Indian J Physiol Pharmacol. 2002;46: 1-5.
36. Kohen R, Gati I. Skin low molecular weight antioxidants and their role in aging and in oxidative stress. Toxicol. 2000;148: 149-157.
37. Aruoma OI. Free radicals, antioxidants and international nutrition. Asia Pac J Clin Nutr. 1999;8: 53-63.
38. Bont RD, van Larebeke N. Endogenous DNA damage in humans: a review of quantitative data. Mutagenesis. 2004;3: 169-185.
39. Das D K, Chakraborty A, Bhattacharjee S, Dey S. Biosynthesis of stabilised gold nanoparticle using an aglycone flavonoid, Quercetin. J Exp Nanosci. 2012;iFirst: 1-7.