Hypoglycemic activity of ethanolic extract of Aphyllorchis montana induced by streptozocin in rats

International Journal of PharmTech Research

Volumn 5, Issue 2, 2013, Pages 320-323

  Thalla, Sreenu ^a   Venkata Ramana, K ^a   Tammu, Jyothibasu ^a   Napa, Delhiraj ^a  

^a ASN Pharmacy College   (India)

Author keywords

Aphyllorchis montana; Hypoglycemic; Streptozocin

Indexed keywords

ANTIDIABETIC AGENT; APHYLLORCHIS MONTANA EXTRACT; GLUCOSE; GLUTATHIONE; PLANT EXTRACT; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; BULIMIA; CONTROLLED STUDY; DIABETES MELLITUS; FLUID INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSURIA; INTESTINE ABSORPTION; MALE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; POLYDIPSIA; RAT; WEIGHT GAIN;

EID: 84879144670     PISSN: 09744304     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Mohanty P, Hamouda W, Garg R, Aljada A, Ghanim H, Dandona P. Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes. J Clin Endocrinol Metab 2000;85:2970-2973
2. Kameswara Rao B, Renuka Sudarshan P, Rajasekhar MD, Nagaraju N, Appa Rao Ch. Hypoglycemic activity of Terminalia pallida fruit in alloxan-induced diabetic rats. J Ethnopharmacol, 2003; 85:169-172.
3. Burcelin R, Eddouks M, Maury J, Kande J, Assan R, Girard J. Excessive glucose production, rather than insulin resistance, accounts for hyperglycemia in recent-onset streptozotocin-diabetic rats. Diabetologia, 1995; 38:283-290
4. Kamesawara BR, Giri R, Kesavulu MM., Apparao CH. Effect of oral administration of bark extracts of Pterocarpus santalinus L. on blood glucose level in experimental animals. J of Ethnopharmacology.2000; 74: 69-74.
5. Yoshida K, Hirokawa J, Tagami S. Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux. Diabetologia 1995;38:201-210.
6. Paolisso G, Di Maro G, Pizza. Plasma GSH/GSSG affects glucose homeostasis in healthy subjects an NIDDM. Am J Physiol 1992;263: E435-440.
7. Jacot E, Assal JPH. Regulation de la glycemie. Dans: Pharmacologie des concepts Fondamentaux aux Applications Therapeutiques. Schorderet, in: Frison-Roche et Slatkine (Ed.), 1989; 481-494.
8. Sreenu Thalla, Bhavani Pentela, Tharangini K, Geethanjali J, GovindaReddy T, Venkata Lakshmi D. Hypo-glycemic activity of ethanolic extract of Aphyllorchis montana on Alloxan induce diabetes in rats. 2012. IJCPS. Vol 3(3):41-45.
9. Ali L, Azad Khan AK, Mamun MIR, Mosihuzzaman M, Nahar N, Nur-E-Alan M., Rokeya B. Studies on the hypoglycaemic effects of fruits pulp, seed and whole plant of Momordica charantia on normal and diabetic model rats. Planta Medica. 1993; 59: 408-412.
10. Kamanyi A, Djamen D, Nkeh B. Hypoglycemic properties of the aqueous roots extract of Morinda lucida study in the mouse. Phytotherapy Research. 1994; 8: 369-371.
11. Rokeya B, Nahar N, Ali L, Hassan Z, Nure-EAlam M, Chowdhury SN, et al. Effects of five medicinal plants on blood glucose levels in non-diabetic and diabetic model rats. Diabetes Research. 1999; 34:219-228.
12. Shanmugasundaram ERB, Gopinath KL, Shanmugasundaram KR, Rajendran VM. Possible regeneration of the islets of Langerhans in streptozotocin-diabetes rats given Gymnema sylvestre leaf extracts. J of Ethnopharmacol. 1990; 30: 265-279.