Histamine enhances HIV-1-induced modulation of dendritic cells to skew naïve T cell differentiation toward regulatory T cells

Virology

Volumn 442, Issue 2, 2013, Pages 163-172

  Zhai, Rong Rong ^a,b   Jiang, Ai Ping ^b   Wang, Hai Bo ^b   Ma, Li ^b,c   Ren, Xiao Xin ^b,c   Jiang, Jin Feng ^b   Wu, Li ^d   Wei, Ji Fu ^a   Wang, Jian Hua ^b  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b INSTITUTE PASTEUR OF SHANGHAI   (China)

^c SOOCHOW UNIVERSITY   (China)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

Dendritic cells; Histamine; HIV 1; Indoleamine 2,3 dioxygenase; Regulatory T cells

Indexed keywords

CD45RA ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTAMINE; HISTAMINE RECEPTOR; HISTAMINE RECEPTOR 2; HISTAMINE RECEPTOR 3; HLA DR ANTIGEN; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 10; INTERLEUKIN 12; MESSENGER RNA; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE DEFICIENCY; IMMUNOMODULATION; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; TH17 CELL;

CELLS, CULTURED; DENDRITIC CELLS; HISTAMINE; HIV-1; HUMANS; IMMUNOLOGIC FACTORS; INTERLEUKIN-10; INTERLEUKIN-12; T-LYMPHOCYTES, REGULATORY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84879136583     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.04.009     Document Type: Article

References (54)

1. Baumer W., Wendorff S., Gutzmer R., Werfel T., Dijkstra D., Chazot P., Stark H., Kietzmann M. Histamine H4 receptors modulate dendritic cell migration through skin-immunomodulatory role of histamine. Allergy 2008, 63(10):1387-1394.
2. Boasso A., Shearer G.M. How does indoleamine 2,3-dioxygenase contribute to HIV-mediated immune dysregulation. Curr. Drug Metab. 2007, 8(3):217-223.
3. Boasso A., Herbeuval J.P., Hardy A.W., Anderson S.A., Dolan M.J., Fuchs D., Shearer G.M. HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells. Blood 2007, 109(8):3351-3359.
4. Boasso A., Vaccari M., Hryniewicz A., Fuchs D., Nacsa J., Cecchinato V., Andersson J., Franchini G., Shearer G.M., Chougnet C. Regulatory T-cell markers, indoleamine 2,3-dioxygenase, and virus levels in spleen and gut during progressive simian immunodeficiency virus infection. J. Virol. 2007, 81(21):11593-11603.
5. Cecchinato V., Trindade C.J., Laurence A., Heraud J.M., Brenchley J.M., Ferrari M.G., Zaffiri L., Tryniszewska E., Tsai W.P., Vaccari M., Parks R.W., Venzon D., Douek D.C., O'Shea J.J., Franchini G. Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques. Mucosal Immunol. 2008, 1(4):279-288.
6. Chevalier M.F., Weiss L. The split personality of regulatory T cells in HIV infection. Blood 2012.
7. Clerici M., Shearer G.M. The Th1-Th2 hypothesis of HIV infection: new insights. Immunol. Today 1994, 15(12):575-581.
8. Dandekar S., George M.D., Baumler A.J. Th17 cells, HIV and the gut mucosal barrier. Curr. Opin. HIV AIDS 2010, 5(2):173-178.
9. de Paulis A., Florio G., Prevete N., Triggiani M., Fiorentino I., Genovese A., Marone G. HIV-1 envelope gp41 peptides promote migration of human Fc epsilon RI+ cells and inhibit IL-13 synthesis through interaction with formyl peptide receptors. J. Immunol. 2002, 169(8):4559-4567.
10. Elhed A., Unutmaz D. Th17 cells and HIV infection. Curr. Opin. HIV AIDS 2010, 5(2):146-150.
11. Favre D., Mold J., Hunt P.W., Kanwar B., Loke P., Seu L., Barbour J.D., Lowe M.M., Jayawardene A., Aweeka F., Huang Y., Douek D.C., Brenchley J.M., Martin J.N., Hecht F.M., Deeks S.G., McCune J.M. Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Sci. Transl. Med. 2010, 2(32):32ra36.
12. Ferstl R., Akdis C.A., O'Mahony L. Histamine regulation of innate and adaptive immunity. Front Biosci. 2012, 17:40-53.
13. Florio G., Petraroli A., Patella V., Triggiani M., Marone G. The immunoglobulin superantigen-binding site of HIV-1 gp120 activates human basophils. AIDS 2000, 14(8):931-938.
14. Gaardbo J., Hartling H., Ullum H., Nielsen S. CD3+CD8+CD161high Tc17 cells are depleted in HIV-Infection and related to the level of immune reconstitution. J. Int. AIDS Soc. 2012, 15(6):18140.
15. Geng S., Gao Y.D., Yang J., Zou J.J., Guo W. Potential role of store-operated Ca2+ entry in Th2 response induced by histamine in human monocyte-derived dendritic cells. Int. Immunopharmacol. 2012, 12(2):358-367.
16. Hanzlikova J., Sedlacek D., Liska M., Gorcikova J., Vlas T., Amiramini S., Panzner P., Maly M. Histamine increases the level of IFNgamma produced by HIV-1 specific CTLs and this production depends on total IgE level. J. Immunol. Methods 2012, 375(1-2):1-6.
17. Hartigan-O'Connor D.J., Abel K., Van Rompay K.K., Kanwar B., McCune J.M. SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment. Sci. Transl. Med. 2012, 4(136):136ra69.
18. Imamichi H., Lane H.C. Regulatory T cells in HIV-1 infection: the good, the bad, and the ugly. J. Infect. Dis. 2012, 205(10):1479-1482.
19. Jurgens B., Hainz U., Fuchs D., Felzmann T., Heitger A. Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells. Blood 2009, 114(15):3235-3243.
20. Kanwar B., Favre D., McCune J.M. Th17 and regulatory T cells: implications for AIDS pathogenesis. Curr. Opin. HIV AIDS 2010, 5(2):151-157.
21. Li D., Chen J., Jia M., Hong K., Ruan Y., Liang H., Liu S., Zhang X., Zhao H., Peng H., Ma P., Shao Y. Loss of balance between T helper type 17 and regulatory T cells in chronic human immunodeficiency virus infection. Clin. Exp. Immunol. 2011, 165(3):363-371.
22. Li S.Y., Xia H.J., Dai Z.X., Zhang G.H., Fan B., Li M.H., Wang R.R., Zheng Y.T. Dynamics and functions of CD4(+)CD25 (high) regulatory T lymphocytes in Chinese rhesus macaques during the early stage of infection with SIVmac239. Arch. Virol. 2012, 157(5):961-967.
23. Li Y., Ling W., Xu H., Wang M., Wu C. The activation and dynamics of cytokine expression by CD4+ T cells and AIDS progression in HIV-1-infected Chinese individuals. Microb. Pathogens 2012, 53(5-6):189-197.
24. Macal M., Sankaran S., Chun T.W., Reay E., Flamm J., Prindiville T.J., Dandekar S. Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses. Mucosal Immunol. 2008, 1(6):475-488.
25. MacGlashan D. Histamine: A mediator of inflammation. J. Allergy Clin. Immunol. 2003, 112(4 Suppl):S53-S59.
26. Manches O., Munn D., Fallahi A., Lifson J., Chaperot L., Plumas J., Bhardwaj N. HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism. J. Clin. Invest. 2008, 118(10):3431-3439.
27. Marone G., Florio G., Petraroli A., Triggiani M., de Paulis A. Role of human FcepsilonRI+ cells in HIV-1 infection. Immunol. Rev. 2001, 179:128-138.
28. Matteoli G., Mazzini E., Iliev I.D., Mileti E., Fallarino F., Puccetti P., Chieppa M., Rescigno M. Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction. Gut 2010, 59(5):595-604.
29. Mazzoni A., Leifer C.A., Mullen G.E., Kennedy M.N., Klinman D.M., Segal D.M. Cutting edge: histamine inhibits IFN-alpha release from plasmacytoid dendritic cells. J. Immunol. 2003, 170(5):2269-2273.
30. Mazzoni A., Young H.A., Spitzer J.H., Visintin A., Segal D.M. Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization. J. Clin. Invest. 2001, 108(12):1865-1873.
31. McIlroy A., Caron G., Blanchard S., Fremaux I., Duluc D., Delneste Y., Chevailler A., Jeannin P. Histamine and prostaglandin E up-regulate the production of Th2-attracting chemokines (CCL17 and CCL22) and down-regulate IFN-gamma-induced CXCL10 production by immature human dendritic cells. Immunology 2006, 117(4):507-516.
32. McKinnon L.R., Kaul R. Quality and quantity: mucosal CD4+ T cells and HIV susceptibility. Curr. Opin. HIV AIDS 2012, 7(2):195-202.
33. Moreno-Fernandez M.E., Presicce P., Chougnet C.A. Homeostasis and function of regulatory T cells in HIV/SIV infection. J. Virol. 2012, 86(19):10262-10269.
34. Nilsson J., Boasso A., Velilla P.A., Zhang R., Vaccari M., Franchini G., Shearer G.M., Andersson J., Chougnet C. HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS. Blood 2006, 108(12):3808-3817.
35. O'Mahony L., Akdis M., Akdis C.A. Regulation of the immune response and inflammation by histamine and histamine receptors. J. Allergy Clin. Immunol. 2011, 128(6):1153-1162.
36. Pallotta M.T., Orabona C., Volpi C., Vacca C., Belladonna M.L., Bianchi R., Servillo G., Brunacci C., Calvitti M., Bicciato S., Mazza E.M., Boon L., Grassi F., Fioretti M.C., Fallarino F., Puccetti P., Grohmann U. Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells. Nat. Immunol. 2011, 12(9):870-878.
37. Patella V., Florio G., Petraroli A., Marone G. HIV-1 gp120 induces IL-4 and IL-13 release from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE. J. Immunol. 2000, 164(2):589-595.
38. Pedersen M., Nielsen C.M., Permin H. HIV antigen-induced release of histamine from basophils from HIV infected patients. Mechanism and relation to disease progression and immunodeficiency. Allergy 1991, 46(3):206-212.
39. Pedersen M., Permin H., Bendtzen K., Norn S. Cytokine-induced release of histamine from basophil leukocytes from AIDS patients. Agents Actions 1990, 30(1-2):294-296.
40. Prendergast A., Prado J.G., Kang Y.H., Chen F., Riddell L.A., Luzzi G., Goulder P., Klenerman P. HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells. AIDS 2010, 24(4):491-502.
41. Presicce P., Orsborn K., King E., Pratt J., Fichtenbaum C.J., Chougnet C.A. Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy. PLoS One 2011, 6(12):e28118.
42. Presicce P., Shaw J.M., Miller C.J., Shacklett B.L., Chougnet C.A. Myeloid dendritic cells isolated from tissues of SIV-infected Rhesus macaques promote the induction of regulatory T cells. AIDS 2012, 26(3):263-273.
43. Prussin C., Metcalfe D.D. 4. IgE, mast cells, basophils, and eosinophils. J. Allergy Clin. Immunol. 2003, 111(Suppl. 2):S486-S494.
44. Raffatellu M., Santos R.L., Verhoeven D.E., George M.D., Wilson R.P., Winter S.E., Godinez I., Sankaran S., Paixao T.A., Gordon M.A., Kolls J.K., Dandekar S., Baumler A.J. Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut. Nat. Med. 2008, 14(4):421-428.
45. Rubbo P.A., Tuaillon E., Bollore K., Foulongne V., Bourdin A., Nagot N., Van de Perre P., Desgranges C., Israel-Biet D., Vendrell J.P. The potential impact of CD4+ T cell activation and enhanced Th1/Th2 cytokine ratio on HIV-1 secretion in the lungs of individuals with advanced AIDS and active pulmonary infection. Clin. Immunol. 2011, 139(2):142-154.
46. Schneider E., Leite-de-Moraes M., Dy M. Histamine, immune cells and autoimmunity. Adv. Exp. Med. Biol. 2010, 709:81-94.
47. Shaw J.M., Hunt P.W., Critchfield J.W., McConnell D.H., Garcia J.C., Pollard R.B., Somsouk M., Deeks S.G., Shacklett B.L. Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers. J. Virol. 2011, 85(21):11422-11434.
48. Shen C.J., Jia Y.H., Tian R.R., Ding M., Zhang C., Wang J.H. Translation of Pur-alpha is targeted by cellular miRNAs to modulate the differentiation-dependent susceptibility of monocytes to HIV-1 infection. FASEB J. 2012, 26(11):4755-4764.
49. Simon T., Laszlo V., Falus A. Impact of histamine on dendritic cell functions. Cell Biol. Int. 2011, 35(10):997-1000.
50. Singh A., Vajpayee M., Ali S.A., Mojumdar K., Chauhan N.K., Singh R. HIV-1 diseases progression associated with loss of Th17 cells in subtype 'C' infection. Cytokine 2012, 60(1):55-63.
51. St Gelais C., Coleman C.M., Wang J.H., Wu L. HIV-1 Nef enhances dendritic cell-mediated viral transmission to CD4+ T cells and promotes T-cell activation. PLoS One 2012, 7(3):e34521.
52. Sun C., Jiang Y., Sun L., Shang H., Zhao Y. The characteristics of Th1/Th2 cytokine receptors on monocytes in untreated patients of long term nonprogressor or chronic HIV infection. Curr. Mol. Med. 2012, 12(8):1028-1039.
53. Taub D.D., Mikovits J.A., Nilsson G., Schaffer E.M., Key M.L., Petrow-Sadowski C., Ruscetti F.W. Alterations in mast cell function and survival following in vitro infection with human immunodeficiency viruses-1 through CXCR4. Cell Immunol. 2004, 230(2):65-80.
54. Williams, A., Steffens, F., Reinecke, C., Meyer, D., 2013. The Th1/Th2/Th17 cytokine profile of HIV-infected individuals: a multivariate cytokinomics approach. Cytokine 61, 521-526.