The clinical and economic costs of delirium after surgical resection for esophageal malignancy

Annals of Surgery

Volumn 258, Issue 1, 2013, Pages 77-81

  Markar, Sheraz R ^a   Smith, Ian A ^a   Karthikesalingam, Alan ^a   Low, Donald E ^a  

^a VIRGINIA MASON MEDICAL CENTER   (United States)

Author keywords

Delirium; Elderly; Esophageal cancer; Esophagectomy; Surgery

Indexed keywords

ADJUVANT THERAPY; ADULT; AGED; ANASTOMOSIS LEAKAGE; ARTICLE; CANCER SURGERY; CHARLSON COMORBIDITY INDEX; COMORBIDITY; COST OF ILLNESS; ESOPHAGUS CANCER; ESOPHAGUS RESECTION; FEMALE; GERIATRIC PATIENT; HOSPITAL COST; HUMAN; INCIDENCE; INTENSIVE CARE UNIT; INTUBATION; LENGTH OF STAY; MAJOR CLINICAL STUDY; MAJOR SURGERY; MALE; PNEUMONIA; PNEUMOTHORAX; POSTOPERATIVE DELIRIUM; PRIORITY JOURNAL; RISK FACTOR; SURVIVAL; URINARY TRACT INFECTION;

ADULT; AGED; AGED, 80 AND OVER; CHEMORADIOTHERAPY; CHI-SQUARE DISTRIBUTION; COMORBIDITY; DELIRIUM; ESOPHAGEAL NEOPLASMS; ESOPHAGECTOMY; FEMALE; HUMANS; LENGTH OF STAY; LOGISTIC MODELS; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; STATISTICS, NONPARAMETRIC; SURVIVAL RATE;

EID: 84879097596     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e31828545c1     Document Type: Article

References (49)

1. Geriatric Review Syllabus-A Core Curriculum in Geriatric Medicine. 6th ed. New York: American Geriatrics Society; 2006.
2. Etzioni DA, Liu JH, Maggard MA, et al. The aging population and its impact on the surgery workforce. Ann Surg. 2003;238:170-177.
3. Poon RT, Law SY, Chu KM, et al. Esophagectomy for carcinoma of the esophagus in the elderly: results of current surgical management. Ann Surg. 1998;227:357-364.
4. Sabel MS, Smith JL, Nava HR, et al. Esophageal resection for carcinoma in patients older than 70 years. Ann Surg Oncol. 2002;9:210-214.
5. Rahamim JS, Murphy GJ, Awan Y, et al. The effect of age on the outcome of surgical treatment for carcinoma of the oesophagus and gastric cardia. Eur J Cardiothorac Surg. 2003;23:805-810.
6. Robinson TN, Raeburn CD, Tran ZV, et al. Postoperative delirium in the elderly: risk factors and outcomes. Ann Surg. 2009;249:173-178.
7. Inouye SK. Delirium in older patients. N Engl J Med. 2006;354:1157-1165.
8. Lipowski ZJ. Delirium (acute confusional states). JAMA. 1987;258:1789-1792.
9. Inouye SK, Charpentier PA. Precipitating factors for delirium in hospitalized elderly persons: predictive model and interrelationship with baseline vulnerability. JAMA. 1996;275:852-857.
10. Marcantonio ER, Goldman L, Mangione CM, et al. A clinical prediction rule for delirium after elective noncardiac surgery. JAMA. 1994;271:134-139.
11. Millar HR. Psychiatric morbidity in elderly surgical patients. Br J Psychiatry. 1981;138:17-20.
12. Seymore DG, Pringle R. Post-operative complications in the elderly surgical patient. Gerontology. 1983;29:262-270.
13. Rice KL, Bennett M, Gomez M, et al. Nurses' recognition of delirium in the hospitalized older adult. Clin Nurse Spec. 2011;25:299-311.
14. Rolfson DB, Ma Elhaney JE, Rockwood K, et al. Incidence and risk factors for delirium and other adverse outcomes in older adults after coronary artery bypass graft surgery. Can J Cardiol. 1999;15:771-776.
15. Ganai S, Lee KF, Merrill A, et al. Adverse outcomes of geriatric patients undergoing abdominal surgery who are at high risk for delirium. Arch Surg. 2007;142:1072-1078.
16. Low DE, Kunz S, Schembre D, et al. Esophagectomy-it's not just about mortality anymore: standardized perioperative clinical pathways improved outcomes in patients with esophageal cancer. J Gastrointest Surg. 2007;11:1395-1402.
17. Cerfolio RJ, Bryant AS, Bass CS, et al. Fast tracking after Ivor Lewis esophagogastrectomy. Chest. 2004;126:1187-1194.
18. Munitiz V, Martinez-de-Haro LF, Ortiz A, et al. Effectiveness of a written clinical pathway for enhanced recovery after transthoracic (Ivor Lewis) oesophagectomy. Br J Surg. 2010;97:714-718.
19. Zehr KJ, Dawson PB, Yang SC, et al. Standardized clinical care pathways for major thoracic cases reduce hospital costs. Ann Thorac Surg. 1998;66:914-919.
20. Wallbridge HR, Benoit AG, Staley D, et al. Risk factors for postoperative cognitive and functional difficulties in abdominal aortic aneurysm patients: a three month follow-up. Int J Geriatr Psychiatry. 2011;26:818-824.
21. Martin BJ, Buth KJ, Arora RC, et al. Delirium: a cause for concern beyond the immediate postoperative period. Ann Thorac Surg. 2012;93:1114-1120.
22. Takeno S, Takahashi Y, Watanabe S, et al. Esophagectomy in patients aged over 80 years with esophageal cancer. Hepatogastroenterology. 2008;55:453-456.
23. Liu HC, Chen YC, Chen CH, et al. Esophagectomy in elderly patients with esophageal cancer. Int J Gerontol. 2010;4:176-179.
24. Tei M, Ikeda M, Haraguchi N, et al. Risk factors for postoperative delirium in elderly patients with colorectal cancer. Surg Endosc. 2010;24:2135-2139.
25. Pitkala KH, Laurila JV, Strandberg TE, et al. Multicomponent geriatric intervention for elderly inpatients with delirium: effects on costs and related quality of life. J Gerontol A Biol Sci Med Sci. 2008;63:56-61.
26. Leslie DL, Marcantonio ER, Zhang Y, et al. One-year health care costs associated with delirium in the elderly population. Arch Intern Med. 2008;168:27-32.
27. Han JH, Shintani A, Eden S, et al. Delirium in the emergency department: an independent predictor of death within 6 months. Ann Emerg Med. 2010;56:244-252.
28. Demeure MJ, Fain MJ. The elderly surgical patient and postoperative delirium. J Am Coll Surg. 2006;203:752-757.
29. Ansaloni L, Catena F, Chattat R, et al. Risk factors and incidence of postoperative delirium in elderly patients after elective and emergency surgery. Br J Surg. 2010;97:273-280.
30. Cjis TM, Verhoef C, Steyerberg EW, et al. Outcome of esophagectomy for cancer in Elderly patients. Ann Thorac Surg. 2010;90:900-907.
31. Bonavina L, Incarbone R, Saino G, et al. Clinical outcome and survival after esophagectomy for carcinoma in elderly patients. Dis Esophagus. 2003;16:270-272.
32. Robinson TN, Eiseman B, Wallace JI, et al. Redefining geriatric preoperative assessment using frailty, disability and co-morbidity. Ann Surg. 2009;250:449-455.
33. Brouquet A, Cudennec T, Benoist S, et al. Impaired mobility, ASA status and administration of tramadol are risk factors for postoperative delirium in patients aged 75 years or more after major abdominal surgery. Ann Surg. 2010;251:759-765.
34. Dasgupta M, Dumbrell AC. Preoperative risk assessment for delirium after noncardiac surgery: a systematic review. J Am Geriatr Soc. 2006;54:1578-1589.
35. Inouye SK, Bogardus ST, Jr, Charpentier PA, et al. A multicomponent intervention to prevent delirium in hospitalized older patients. N Engl J Med. 1999;340:669-676.
36. Pol RA, Van Leeuwen BL, Visser L, et al. Standardised frailty indicator as predictor for postoperative delirium after vascular surgery: a prospective cohort study. Eur J Vasc Endosvasc Surg. 2011;42:824-830.
37. Afonso A, Scurlock C, Reich D, et al. Predictive model for postoperative delirium in cardiac surgical patients. Semin Cardiothorac Vasc Anesth. 2010;14:212-217.
38. O'Keeffe ST, Lavan JN. Predicting delirium in elderly patients: development and validation of a risk-stratification model. Age Ageing. 1996;25:317-321.
39. Satz P. Brain reserve capacity on symptom onset after brain injury: a formulation and review of evidence for threshold theory. Neuropsychology. 1993;273-295.
40. Stern Y. The concept of cognitive reserve: a catalyst for research. J Clin Exp Neuropyschol. 2003;25:589-593.
41. Franco JG, Valencia C, Bernal C, et al. Relationship between cognitive status at admission and incident delirium in older medical inpatients. J Neuropsychiatry Clin Neurosci. 2010;22:329-337.
42. Inouye SK, Van Dyck CH, Alessi CA, et al. Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med. 1990;113:941-948.
43. Ely EW, Shintani A, Truman B, et al. Delirium as a predictor ofmortality in mechanically ventilated patients in the intensive care unit. JAMA. 2004;291:1753-1762.
44. Marcantonio ER, Flacker JM, Michaels M, et al. Delirium is independently associated with poor functional recovery after hip fracture. J Am Geriatr Soc. 2000;48:618-624.
45. O'Mahony R, Murthy L, Akunne A, et al. Guideline Development Group. Synopsis of National Institute for Health and Clinical Excellence guideline for prevention of delirium. Ann Intern Med. 2011;154:746-751.
46. Mouchoux C, Rippert P, Duclos A, et al. Impact of a multifaceted program to prevent postoperative delirium in the elderly: the CONFUCIUS stepped wedge protocol. BMC Geriatr. 2011;11:25.
47. Siddiqi N, Stockdale R, Britton AM, et al. Interventions for preventing delirium in hospitalized patients. Cochrane Database Syst Rev. 2007:CD005563.
48. Ono H, Taguchi T, Kido Y, et al. The usefulness of bright light therapy for patients after oesophagectomy. Intensive Crit Care Nurs. 2011;27:158-166.
49. Rudin A, Flisberg P, Johansson J, et al. Thoracic epidural analgesia or intravenous morphine analgesia after thoracoabdominal esophagectomy: a prospective follow-up of 201 patients. J Cardiothorac Vasc Anesth. 2005;19:350-357.