The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions

Journal of Molecular Biology

Volumn 425, Issue 13, 2013, Pages 2359-2371

  Hegde, Muralidhar L ^a   Tsutakawa, Susan E ^b   Hegde, Pavana M ^a   Holthauzen, Luis Marcelo F ^a   Li, Jing ^c   Oezguen, Numan ^a   Hilser, Vincent J ^c   Tainer, John A ^b   Mitra, Sankar ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

DNA repair; electrostatic interactions; intrinsically unstructured region; oxidative DNA damage; protein stability

Indexed keywords

DNA GLYCOSYLTRANSFERASE; NEI ENDONUCLEASE VIII LIKE PROTEIN 1; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; CRYSTAL STRUCTURE; DELETION MUTANT; DNA BINDING; ENZYME ACTIVITY; ESCHERICHIA COLI; EXCISION REPAIR; FLUORESCENCE; FLUORESCENCE ANALYSIS; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; STATIC ELECTRICITY; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI; MAMMALIA;

EID: 84879097056     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.03.030     Document Type: Article

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