Coding variants in ARMS2 and the risk of age-related macular degeneration

JAMA Ophthalmology

Volumn 131, Issue 6, 2013, Pages 804-805

  Wang, Gaofeng ^a   Scott, William K ^a   Agarwal, Anita ^a   Haines, Jonathan L ^a   Pericak Vance, Margaret A ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARMS2 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ALLELE; GENE LOCUS; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; LETTER; NONSENSE MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA MACULA AGE RELATED DEGENERATION; SMOKING; STOP CODON;

CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HAPLOTYPES; HUMANS; MACULAR DEGENERATION; MALE; ODDS RATIO; PHENOTYPE; PROMOTER REGIONS, GENETIC; PROTEINS; RISK ASSESSMENT; RISK FACTORS; SERINE ENDOPEPTIDASES; UNITED STATES;

EID: 84879036778     PISSN: 21686165     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamaophthalmol.2013.589     Document Type: Letter

References (2)

1. Yang Z, Tong Z, Chen Y, et al. Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration. PLoS Genet. 2010;6(2):e1000836.
2. Friedrich U, Myers CA, Fritsche LG, et al. Risk- and non-risk-associated variants at the 10q26 AMD locus influence ARMS2 mRNA expression but exclude pathogenic effects due to protein deficiency. Hum Mol Genet. 2011;20(7):1387-1399.