Design, synthesis and screening of some novel benzoxazole based 1,3,4-oxadiazoles as potential antimicrobial agents

Chinese Chemical Letters

Volumn 24, Issue 7, 2013, Pages 625-628

  Vodela, Sunil ^a   Mekala, Raghu Vardhan Reddy ^b   Danda, Ravinder Reddy ^c   Kodhati, Venkateshwarlu ^d  

^a Talla Padmavathi College of Engineering   (India)

^b KAKATIYA UNIVERSITY   (India)

^c Mahathma Gandhi University   (India)

^d Vaagdevi College of Pharmacy   (India)

Author keywords

1,3,4 Oxadiazoles; Antimicrobial activity; Benzoxazoles

Indexed keywords

EID: 84879035566     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cclet.2013.04.005     Document Type: Article

References (19)

1. M.P. Hutt, E.F. Elstager, and L.M. Werbet 2-Phenyl-5-(trichloromethyl)-1, 3,4-oxadiazoles, a new class of anti-malarial substances J. Heterocycl. Chem. 7 1970 511 581
2. F. Omar, N. Mahfouz, and M. Rahman Design, synthesis and antiinflammatory activity of some 1,3,4-oxadiazole derivatives Eur. J. Med. Chem. 31 1996 819 825
3. A. Zarghi, S.A. Tabatabai, and M. Faizi Synthesis and anticonvulsant activity of new 2-substituted-5-(2-benzyloxyphenyl)-1,3,4-oxadiazoles Bioorg. Med. Chem. Lett. 15 2005 1863 1865
4. A. Husain, and M. Ajmal Synthesis of novel 1,3,4-oxadiazole derivatives and their biological properties Acta Pharm. 59 2009 223 233
5. S.L. Gaonkar, and K.M. Rai Synthesis and antimicrobial studies of a new series of 2-{4-[2-(5-ethylpyridin-2-yl)ethoxy]phen-yl}-5-substituted-1,3,4- oxadiazoles Eur. J. Med. Chem. 41 2006 841 846
6. M.A. Ali, and M.S. Yar Oxadiazole mannich bases: synthesis and antimycobacterial activity Bioorg. Med. Chem. Lett. 17 2007 3314 3316
7. Z.H. Luo, S.Y. He, and B.Q. Chen Synthesis and in vitro antitumor activity of 1,3,4-oxadiazole derivatives based on benzisoselenazolone Chem. Pharm. Bull. 60 2012 887 891
8. V.J. Ram, and H.N. Pandey Synthesis and anti-inflammatory activity of benzal-3-pentadecylaryloxyalkyl carboxylic acid hydrazides and 2-benzalamino-5-(3′-pentadecylaryloxyalkyl)-1,3,4-oxadiazoles Eur. J. Med. Chem. 25 1990 541 548
9. P.J. Shirote, and M.S. Bhatia Synthesis, characterization and antiinflammatory activity of 5-{[((5-substituted-aryl)-1,3,4-thiadiazol-2-yl) thio]-n-alkyl}-1,3,4-oxadiazole-2-thiol Chin. J. Chem. 28 2010 1429 1436
10. V. Padmavathi, G.S. Reddy, A. Padmaja, P. Kondaiah, and A. Shazia Synthesis, antimicrobial and cytotoxic activities of 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles Eur. J. Med. Chem. 44 2009 2106 2112
11. B. Jayashankar, K.M.L. Rai, N. Baskaran, and H.S.S. Shazia Synthesis and pharmacological evaluation of 1,3,4-oxadiazole bearing bis(heterocycle) derivatives as anti-inflammatory and analgesic agents Eur. J. Med. Chem. 44 2009 3898 3902
12. F.A. Omar, N.M. Mahfouz, and M.A. Rahman Design, synthesis and antiinflammatory activity of some 1,3,4-oxadiazole derivatives Eur. J. Med. Chem. 31 1996 819 825
13. T. Hisano, M. Ichikawa, K. Tsumoto, and M. Tasaki Synthesis of benzoxazoles, benzothiazoles and benzimidazoles and evaluation of their antifungal, insecticidal and herbicidal activities Chem. Pharm. Bull. 30 1982 2996 3004
14. A. Kumar, and D. Kumar Synthesis and antimicrobial activity of metal complexes from 2-(1′/2′-hydroxynaphthyl)benzoxazoles Arkivoc 2007 117 125
15. Y. Katsura, Y. Inoue, and S. Nishino Synthesis and antiulcer activities of imidazo[1,2-a]pyridinylethyl-benzoxazoles and related compounds. A novel class of histamine H2-receptor antagonists Chem. Pharm. Bull. 40 1992 1424 1438
16. R.D. Haugwitz, R.G. Angel, and G.A. Jacobs Synthesis and anthelmintic activities of novel 2-heteroaromatic-substituted isothiocyanatoben-zoxazoles and benzothiazoles J. Med. Chem. 25 1982 969 974
17. C.J. Paget, K. Kisner, R.L. Stone, and D.C. DeLong Immunosuppressive and antiviral activity of benzothiazole and benzoxazoleureas J. Med. Chem. 12 1969 1016 1018
18. T.A. Ozlem, Y. Ilkay, and O. Semih Synthesis and biological activity of some new benzoxazoles Eur. J. Med. Chem. 43 2008 1423 1431
19. R. Cruickshank Medicinal Microbiology. A Guide to Diagnosis and Control of Infection 11th ed. 1986 E & S Livingstone Edinburgh and London, UK pp. 888-902