Hydramacin-1 in action: Scrutinizing the barnacle model

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 7, 2013, Pages 2955-2966

  Michalek, Matthias ^a   Vincent, Bruno ^a   Podschun, Rainer ^b   Joachim Grotzinger ^c   Bechinger, Burkhard ^a   Jung, Sascha ^c  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; EPITOPE; HYDRAMACIN 1; HYDROCARBON; MAGAININ 1; PEPTIDE; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; BARNACLE MODEL; BINDING AFFINITY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HYDROPHOBICITY; LIPID BILAYER; MODEL; NONHUMAN; PHOSPHOLIPID BILAYER; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTEIN STRUCTURE;

ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; BURKHOLDERIA CEPACIA; CELL MEMBRANE; ESCHERICHIA COLI; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPID BILAYERS; LIPIDS; PROTEIN BINDING; PROTEUS MIRABILIS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS HAEMOLYTICUS; STAPHYLOCOCCUS HOMINIS; STATIC ELECTRICITY; STREPTOCOCCUS PNEUMONIAE;

EID: 84879027506     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02498-12     Document Type: Article

References (38)

1. Zasloff M. 2002. Antimicrobial peptides of multicellular organisms. Nature 415:389-395. (Pubitemid 34100944)
2. Jenssen H, Hamill P, Hancock RE. 2006. Peptide antimicrobial agents. Clin. Microbiol. Rev. 19:491-511. (Pubitemid 44137212)
3. Shai Y. 1999. Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. Biochim. Biophys. Acta 1462:55-70.
4. Wilmes M, Cammue BP, Sahl HG, Thevissen K. 2011. Antibiotic activities of host defense peptides: more to it than lipid bilayer perturbation. Nat. Prod. Rep. 28:1350-1358.
5. Jung S, Dingley AJ, Augustin R, Anton-Erxleben F, Stanisak M, Gelhaus C, Gutsmann T, Hammer MU, Podschun R, Bonvin AM, Leippe M, Bosch TC, Grötzinger J. 2009. Hydramacin-1, structure and antibacterial activity of a protein from the basal metazoan Hydra. J. Biol. Chem. 284: 1896-1905.
6. Jung S, Sönnichsen FD, Hung CW, Tholey A, Boidin-Wichlacz C, Haeusgen W, Gelhaus C, Desel C, Podschun R, Waetzig V, Tasiemski A, Leippe M, Grötzinger J. 2012. Macin family of antimicrobial proteins combines antimicrobial and nerve repair activities. J. Biol. Chem. 287: 14246-14258.
7. Bosch TC, Augustin R, Anton-Erxleben F, Fraune S, Hemmrich G, Zill H, Rosenstiel P, Jacobs G, Schreiber S, Leippe M, Stanisak M, Grötzinger J, Jung S, Podschun R, Bartels J, Harder J, Schröder JM. 2009. Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence. Dev. Comp. Immunol. 33:559-569.
8. Dubreil L, Compoint JP, Marion D. 1997. Interaction of puroindolines with wheat flour polar lipids determines their foaming properties. J. Agric. Food Chem. 45:108-116. (Pubitemid 127485759)
9. Chang YC, Ludescher RD. 1994. Local conformation of rabbit skeletal myosin rod filaments probed by intrinsic tryptophan fluorescence. Biochemistry 33:2313-2321. (Pubitemid 24099633)
10. Bolen EJ, Holloway PW. 1990. Quenching of tryptophan fluorescence by brominated phospholipid. Biochemistry 29:9638-9643. (Pubitemid 20355212)
11. Ladokhin AS, Wang L, Steggles AW, Malak H, Holloway PW. 1993. Fluorescence study of a temperature-induced conversion from the "loose" to the "tight" binding form of membrane-bound cytochrome b5. Biochemistry 32:6951-6956. (Pubitemid 23221627)
12. McIntosh TJ, Holloway PW. 1987. Determination of the depth of bromine atoms in bilayers formed from bromolipid probes. Biochemistry 26:1783-1788. (Pubitemid 17047651)
13. Markley JL, Bax A, Arata Y, Hilbers CW, Kaptein R, Sykes BD, Wright PE, Wüthrich K. 1998. Recommendations for the presentation of NMR structures of proteins and nucleic acids. J. Mol. Biol. 280:933-952. (Pubitemid 28345026)
14. Farrow NA, Muhandiram R, Singer AU, Pascal SM, Kay CM, Gish G, Shoelson SE, Pawson T, Forman-Kay JD, Kay LE. 1994. Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation. Biochemistry 33:5984-6003. (Pubitemid 24184605)
15. Delaglio F, Grzesiek S, Vuister GW, Zhu G, Pfeifer J, Bax A. 1995. NMR Pipe: a multidimensional spectral processing system based on UNIX pipes. J. Biomol. NMR 6:277-293.
16. Johnson BA. 2004. Using NMR View to visualize and analyze the NMR spectra of macromolecules. Methods Mol. Biol. 278:313-352.
17. Grzesiek S, Stahl SJ, Wingfield PT, Bax A. 1996. The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR. Biochemistry 35:10256-10261. (Pubitemid 26277283)
18. Aisenbrey C, Bertani P, Bechinger B. 2010. Solid-state NMR investigations of membrane-associated antimicrobial peptides. Methods Mol. Biol. 618:209-233.
19. Salnikov ES, Aisenbrey C, Balandin SV, Zhmak MN, Ovchinnikova TV, Bechinger B. 2011. Structure and alignment of the membrane-associated antimicrobial peptide arenicin by oriented solid-state NMR spectroscopy. Biochemistry 50:3784-3795.
20. Aisenbrey C, Bechinger B. 2004. Tilt and rotational pitch angle of membrane-inserted polypeptides from combined 15N and2Hsolid-state NMR spectroscopy. Biochemistry 43:10502-10512. (Pubitemid 39079321)
21. Bechinger B, Salnikov ES. 2012. The membrane interactions of antimicrobial peptides revealed by solid-state NMR spectroscopy. Chem. Phys. Lipids 165:282-301.
22. Marquette A, Lorber B, Bechinger B. 2010. Reversible liposome association induced by LAH4: a peptide with potent antimicrobial and nucleic acid transfection activities. Biophys. J. 98:2544-2553.
23. Dathe M, Nikolenko H, Meyer J, Beyermann M, Bienert M. 2001. Optimization of the antimicrobial activity of magainin peptides by modification of charge. FEBS Lett. 501:146-150.
24. Beschiaschvili G, Seelig J. 1990. Melittin binding to mixed phosphatidylglycerol/phosphatidylcholine membranes. Biochemistry 29:52-58. (Pubitemid 20033706)
25. Gazit E, Boman A, Boman HG, Shai Y. 1995. Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles. Biochemistry 34:11479-11488.
26. Eftink MR, Ghiron CA. 1976. Exposure of tryptophanyl residues in proteins. Quantitative determination by fluorescence quenching studies. Biochemistry 15:672-680.
27. Raja SM, Rawat SS, Chattopadhyay A, Lala AK. 1999. Localization and environment of tryptophans in soluble and membrane-bound states of a pore-forming toxin from Staphylococcus aureus. Biophys. J. 76:1469-1479. (Pubitemid 29262626)
28. Tortech L, Jaxel C, Vincent M, Gallay J, de Foresta B. 2001. The polar headgroup of the detergent governs the accessibility to water of tryptophan octyl ester in host micelles. Biochim. Biophys. Acta 1514:76-86. (Pubitemid 32769930)
29. Aisenbrey C, Prongidi-Fix L, Chenal A, Gillet D, Bechinger B. 2009. Side chain resonances in static oriented proton-decoupled 15N solid-state NMR spectra of membrane proteins. J. Am. Chem. Soc. 131:6340-6341.
30. Sizun C, Bechinger B. 2002. Bilayer sample for fast or slow magic angle oriented sample spinning solid-state NMR spectroscopy. J. Am. Chem. Soc. 124:1146-1147. (Pubitemid 34169103)
31. Qin L, Sharpe MA, Garavito RM, Ferguson-Miller S. 2007. Conserved lipid-binding sites in membrane proteins: a focus on cytochrome c oxidase. Curr. Opin. Struct. Biol. 17:444-450. (Pubitemid 47451764)
32. Esbjörner EK, Caesar CE, Albinsson B, Lincoln P, Norden B. 2007. Tryptophan orientation in model lipid membranes. Biochem. Biophys. Res. Commun. 361:645-650. (Pubitemid 47238038)
33. Gaede HC, Yau WM, Gawrisch K. 2005. Electrostatic contributions to indole-lipid interactions. J. Phys Chem. B 109:13014-13023. (Pubitemid 40999829)
34. Wimley WC, White SH. 1996. Experimentally determined hydrophobicity scale for proteins at membrane interfaces. Nat. Struct. Biol. 3:842-848. (Pubitemid 26330634)
35. Yau WM, Wimley WC, Gawrisch K, White SH. 1998. The preference of tryptophan for membrane interfaces. Biochemistry 37:14713-14718. (Pubitemid 28487579)
36. Ramachandran R, Heuck AP, Tweten RK, Johnson AE. 2002. Structural insights into the membrane-anchoring mechanism of a cholesteroldependent cytolysin. Nat. Struct. Biol. 9:823-827. (Pubitemid 35257781)
37. Hong Q, Gutierrez-Aguirre I, Barlic A, Malovrh P, Kristan K, Podlesek Z, Macek P, Turk D, Gonzalez-Manas JM, Lakey JH, Anderluh G. 2002. Two-step membrane binding by Equinatoxin II, a pore-forming toxin from the sea anemone, involves an exposed aromatic cluster and a flexible helix. J. Biol. Chem. 277:41916-41924. (Pubitemid 35257504)
38. Gutierrez-Aguirre I, Trontelj P, Macek P, Lakey JH, Anderluh G. 2006. Membrane binding of zebrafish actinoporin-like protein: AF domains, a novel superfamily of cell membrane binding domains. Biochem. J. 398: 381-392. (Pubitemid 44453382)