Mesenchymal stromal cell expansion for cord-blood engraftment

Clinical Advances in Hematology and Oncology

Volumn 11, Issue 3, 2013, Pages 248-250

  de Lima, Marcos ^a  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DIFFERENTIATION; CELL SURVIVAL; CORD BLOOD STEM CELL TRANSPLANTATION; GRAFT VERSUS HOST REACTION; HUMAN; INCIDENCE; LYMPHOCYTE; MESENCHYMAL STROMA CELL; NEUTROPHIL; NOTE; PHASE 2 CLINICAL TRIAL (TOPIC); STEM CELL EXPANSION; THROMBOCYTE; CELL EXPANSION; DISEASE ASSOCIATION; DISEASE REGISTRY; ENGRAFTMENT; HEMATOLOGIC DISEASE; STROMA; UMBILICAL CORD BLOOD;

CD34 ANTIGEN;

CLINICAL TRIALS, PHASE II AS TOPIC; COCULTURE TECHNIQUES; FETAL BLOOD; GRAFT SURVIVAL; HEMATOLOGIC NEOPLASMS; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; RESEARCH; RESEARCH DESIGN; TREATMENT OUTCOME;

EID: 84879016633     PISSN: 15430790     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (5)

1. Delaney C, Bollard CM, Shpall EJ. Cord blood graft engineering. Biol Blood Marrow Transplant. 2013;19(suppl 1):S74-S78.
2. Delaney C, Heimfeld S, Brashem-Stein C, Voorhies H, Manger RL, Bernstein ID. Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution. Nat Med. 2010;16:232-236.
3. de Lima M, McMannis J, Gee A, et al. Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine (TEPA): a phase I trial. Bone Marrow Transpl. 2008;41:771-778.
4. de Lima M, McNiece I, Robinson SN, et al. Cord-blood engraftment with ex vivo mesenchymal-cell coculture. N Engl J Med. 2012;367:2305-2315.
5. Oran B, Shpall E. Umbilical cord blood transplantation: a maturing technology. Hematology Am Soc Hematol Educ Program. 2012;2012:215-222.