Radiotherapy with rectangular fields is associated with fewer clinical failures than conformal fields in the high-risk prostate cancer subgroup: Results from a randomized trial

Radiotherapy and Oncology

Volumn 107, Issue 2, 2013, Pages 134-139

  Heemsbergen, Wilma D ^a   Al Mamgani, Abrahim ^b   Witte, Marnix G ^a   Van Herk, Marcel ^a   Lebesque, Joos V ^a  

^a ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

High risk; Prostate cancer; Subclinical disease; Trial

Indexed keywords

ARTICLE; CANCER PATIENT; CANCER RADIOTHERAPY; FOLLOW UP; HIGH RISK PATIENT; HUMAN; PRIORITY JOURNAL; PROSTATE CANCER; RANDOMIZED CONTROLLED TRIAL (TOPIC); SEMINAL VESICLE;

AGED; DISEASE PROGRESSION; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROSTATIC NEOPLASMS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; RISK FACTORS; TREATMENT FAILURE;

EID: 84879015011     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2013.03.019     Document Type: Article

References (17)

1. D.B. Chism, A.L. Hanlon, E.M. Horwitz, S.J. Feigenberg, and A. Pollack A comparison of the single and double factor high-risk models for risk assignment of prostate cancer treated with 3D conformal radiotherapy Int J Radiat Oncol Biol Phys 59 2004 380 385 (Pubitemid 38622589)
2. P.B. Morgan, A.L. Hanlon, E.M. Horwitz, M.K. Buyyounouski, and A. Pollack Timing of biochemical failure and distant metastatic disease for low-, intermediate- and high-risk prostate cancer after radiotherapy Cancer 110 2007 68 80 (Pubitemid 46986420)
3. F.Y. Feng, Y. Qian, M.H. Stenmark, S. Halverson, K. Blas, and S. Vance Perineural invasion predicts increased recurrence, metastasis, and death from prostate cancer following treatment with dose-escalated radiation therapy Int J Radiat Oncol Biol Phys 81 2011 e361 e367
4. B.S. Teh, M.D. Bastasch, and W.Y. Mai Predictors of extracapsular extension and its radial distance in prostate cancer: Implications for prostate IMRT, brachytherapy and surgery Cancer J 9 2003 454 460 (Pubitemid 44403481)
5. C.K. Poulos, M.O. Koch, J.N. Eble, J.K. Daggy, and L. Cheng Bladder neck invasion is an independent predictor of prostate-specific antigen recurrence Cancer 101 2004 1563 1568 (Pubitemid 39318902)
6. D. Weckermann, R. Dorn, and M. Trefz Sentinel lymph node dissection for prostate cancer: experience with more than 1000 patients J Urol 177 2007 916 920 (Pubitemid 46216337)
7. D.V. Makarov, B.J. Trock, E.B. Humphreys, L.A. Mangold, P.C. Walsh, and J.I. Epstein Updated nomogram to predict pathologic stage of prostate cancer given prostate-specific antigen level, clinical stage, and biopsy Gleason score (Partin tables) based on cases from 2000 to 2005 Urology 69 2007 1095 1101 (Pubitemid 46891611)
8. P. Pommier, S. Chabaud, and J. Lagrange Is there a role for pelvic irradiation in localized prostate adenocarcinoma? Preliminary results of GETUG-01 J Clin Oncol 25 2007 5366 5373 (Pubitemid 350232211)
9. C. Lawton, M. DeSilvio, and M. Roach An update of the phase III trial comparing whole pelvic to prostate only radiotherapy and neoadjuvant to adjuvant total androgen suppression: updated analysis of RTOG 94-13, with emphasis on unexpected hormone/radiation interactions Int J Radiat Oncol Biol Phys 69 2007 646 655 (Pubitemid 47418390)
10. L.K. Morikawa, and M. Roach Pelvic nodal radiotherapy in patients with unfavorable intermediate and high-risk prostate cancer: evidence, rationale, and future directions Int J Radiat Oncol Biol Phys 80 2011 6 16
11. M. Witte, W.D. Heemsbergen, and R. Bohoslavsky Relating dose outside the prostate with freedom from failure in the Dutch trial 68 Gy versus 78 Gy Int J Radiat Oncol Biol Phys 77 2009 131 138
12. P.C. Koper, P. Janssen, and W. van Putten Gastro-intestinal and genito-urinary morbidity after 3D CRT of prostate cancer: observations of a randomized trial Radiother Oncol 73 2004 1 9 (Pubitemid 39304119)
13. A. Bel, M. van Herk, H. Bartelink, and J.V. Lebesque A verification procedure to improve patient set-up accuracy using portal images Radiother Oncol 29 1993 253 260 (Pubitemid 24007867)
14. M. van Herk, P. Remeijer, and J.V. Lebesque Inclusion of geometric uncertainties in treatment plan evaluation Int J Radiat Oncol Biol Phys 52 2002 1407 1422 (Pubitemid 34296500)
15. W.D. Heemsbergen, M.S. Hoogeman, M.G. Witte, S.T. Peeters, L. Incrocci, and J.V. Lebesque Increased risk of biochemical and clinical failure for prostate patients with a large rectum at radiotherapy planning: results from the Dutch trial of 68 Gy versus 78 Gy Int J Radiat Oncol Biol Phys 67 2007 1418 1424 (Pubitemid 46467163)
16. B. Engels, G. Soete, D. Verellen, and G. Storme Conformal arc radiotherapy for prostate cancer: increased biochemical failure in patients with distended rectum on the planning computed tomogram despite image guidance by implanted markers Int J Radiat Oncol Biol Phys 74 2009 388 391
17. J. Adkison, D.R. McHaffie, and S.M. Bentzen Phase I trial of pelvic nodal dose escalation with hypfractionated IMRT for high-risk prostate cancer Int J Radiat Oncol Biol Phys 82 2012 184 190