메뉴 건너뛰기




Volumn 169, Issue 5, 2013, Pages 1178-1188

Increasing doxorubicin activity against breast cancer cells using PPARγ-ligands and by exploiting circadian rhythms

Author keywords

anti proliferative activity; breast cancer; cardiotoxicity; doxorubicin; melatonin; rosiglitazone

Indexed keywords

CIGLITAZONE; CYCLIN D1; DOXORUBICIN; MELATONIN; ROSIGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTINEOPLASTIC ANTIBIOTIC; COLLAGEN; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 84879012934     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12202     Document Type: Article
Times cited : (32)

References (40)
  • 1
    • 34247149015 scopus 로고    scopus 로고
    • The regulation of cyclin D1 degradation: Roles in cancer development and the potential for therapeutic invention
    • Alao JP, (2007). The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention. Mol Cancer 6: 24.
    • (2007) Mol Cancer , vol.6 , pp. 24
    • Alao, J.P.1
  • 2
    • 18144388677 scopus 로고    scopus 로고
    • Selective activation of PPARgamma in breast, colon, and lung cancer cell lines
    • Allred CD, Kilgore MW, (2005). Selective activation of PPARgamma in breast, colon, and lung cancer cell lines. Mol Cell Endocrinol 235: 21-29.
    • (2005) Mol Cell Endocrinol , vol.235 , pp. 21-29
    • Allred, C.D.1    Kilgore, M.W.2
  • 3
    • 34247151073 scopus 로고    scopus 로고
    • Melatonin: Therapeutic and clinical utilization
    • Altun A, Ugur-Altun B, (2007). Melatonin: therapeutic and clinical utilization. Int J Clin Pract 61: 835-845.
    • (2007) Int J Clin Pract , vol.61 , pp. 835-845
    • Altun, A.1    Ugur-Altun, B.2
  • 6
    • 11144346203 scopus 로고    scopus 로고
    • Structural and functional characterisation of cardiac fibroblasts
    • Camelliti P, Borg TK, Kohl P, (2005). Structural and functional characterisation of cardiac fibroblasts. Cardiovasc Res 65: 40-51.
    • (2005) Cardiovasc Res , vol.65 , pp. 40-51
    • Camelliti, P.1    Borg, T.K.2    Kohl, P.3
  • 7
    • 84857055427 scopus 로고    scopus 로고
    • First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: A phase I/II open-label and double-blind study
    • Demetri G, Le Cesne A, Chawla S, Brodowicz T, Maki RG, Bach B, et al.(2012). First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: a phase I/II open-label and double-blind study. Eur J Cancer 48: 547-563.
    • (2012) Eur J Cancer , vol.48 , pp. 547-563
    • Demetri, G.1    Le Cesne, A.2    Chawla, S.3    Brodowicz, T.4    Maki, R.G.5    Bach, B.6
  • 8
    • 77950838898 scopus 로고    scopus 로고
    • Melatonin and doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines
    • Fan LL, Sun GP, Wei W, Wang ZG, Ge L, Fu WZ, et al. (2010). Melatonin and doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines. World J Gastroenterol 16: 1473-1481.
    • (2010) World J Gastroenterol , vol.16 , pp. 1473-1481
    • Fan, L.L.1    Sun, G.P.2    Wei, W.3    Wang, Z.G.4    Ge, L.5    Fu, W.Z.6
  • 9
    • 80052032897 scopus 로고    scopus 로고
    • Single-agent pegylated liposomal doxorubicin (PLD) in the treatment of metastatic breast cancer: Results of an Austrian observational trial
    • Fiegl M, Mlineritsch B, Hubalek M, Bartsch R, Pluschnig U, Steger GG, (2011). Single-agent pegylated liposomal doxorubicin (PLD) in the treatment of metastatic breast cancer: results of an Austrian observational trial. BMC Cancer 11: 373.
    • (2011) BMC Cancer , vol.11 , pp. 373
    • Fiegl, M.1    Mlineritsch, B.2    Hubalek, M.3    Bartsch, R.4    Pluschnig, U.5    Steger, G.G.6
  • 10
    • 0035099803 scopus 로고    scopus 로고
    • Ternary combination of irinotecan, fluorouracil-folinic acid and oxaliplatin: Results on human colon cancer cell lines
    • Fischel JL, Rostagno P, Formento P, Dubreuil A, Etienne MC, Milano G, (2001). Ternary combination of irinotecan, fluorouracil-folinic acid and oxaliplatin: results on human colon cancer cell lines. Br J Cancer 84: 579-585.
    • (2001) Br J Cancer , vol.84 , pp. 579-585
    • Fischel, J.L.1    Rostagno, P.2    Formento, P.3    Dubreuil, A.4    Etienne, M.C.5    Milano, G.6
  • 11
    • 0029936580 scopus 로고    scopus 로고
    • Growth arrest and non-apoptotic cell death associated with the suppression of c-myc expression in MCF-7 breast tumor cells following acute exposure to doxorubicin
    • Fornari FA, Jarvis W, Grant S, Orr MS, Randolph JK, White FKH, et al. (1996). Growth arrest and non-apoptotic cell death associated with the suppression of c-myc expression in MCF-7 breast tumor cells following acute exposure to doxorubicin. Biochem Pharmacol 51: 931-940.
    • (1996) Biochem Pharmacol , vol.51 , pp. 931-940
    • Fornari, F.A.1    Jarvis, W.2    Grant, S.3    Orr, M.S.4    Randolph, J.K.5    White, F.K.H.6
  • 12
    • 0032032987 scopus 로고    scopus 로고
    • Melatonin enhances tamoxifen's ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation
    • García J, Reiter R, Ortiz G, Oh C, Tang L, Yu B, et al. (1998). Melatonin enhances tamoxifen's ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation. J Membr Biol 162: 59-65.
    • (1998) J Membr Biol , vol.162 , pp. 59-65
    • García, J.1    Reiter, R.2    Ortiz, G.3    Oh, C.4    Tang, L.5    Yu, B.6
  • 13
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of thenthracycline antibiotics adriamycin and daunorubicin
    • Gewirtz D, (1999). A critical evaluation of the mechanisms of action proposed for the antitumor effects of thenthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 57: 727-741.
    • (1999) Biochem Pharmacol , vol.57 , pp. 727-741
    • Gewirtz, D.1
  • 14
    • 0035266333 scopus 로고    scopus 로고
    • Experimental chronotherapy of mouse mammary adenocarcinoma MA13/C with docetaxel and doxorubicin as single agents and in combination
    • Granda TG, Filipski E, D'Attino RM, Vrignaud P, Anjo A, Bissery MC, et al. (2001). Experimental chronotherapy of mouse mammary adenocarcinoma MA13/C with docetaxel and doxorubicin as single agents and in combination. Cancer Res 61: 1996-2001.
    • (2001) Cancer Res , vol.61 , pp. 1996-2001
    • Granda, T.G.1    Filipski, E.2    D'Attino, R.M.3    Vrignaud, P.4    Anjo, A.5    Bissery, M.C.6
  • 15
    • 33846549188 scopus 로고    scopus 로고
    • Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells
    • Greco F, Vicent MJ, Gee S, Jones AT, Gee J, Nicholson RI, et al. (2007). Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells. J Control Release 117: 28-39.
    • (2007) J Control Release , vol.117 , pp. 28-39
    • Greco, F.1    Vicent, M.J.2    Gee, S.3    Jones, A.T.4    Gee, J.5    Nicholson, R.I.6
  • 16
    • 67649236122 scopus 로고    scopus 로고
    • Melatonin: Signaling mechanisms of a pleiotropic agent
    • Hardeland R, (2009). Melatonin: signaling mechanisms of a pleiotropic agent. Biofactors 35: 183-192.
    • (2009) Biofactors , vol.35 , pp. 183-192
    • Hardeland, R.1
  • 18
    • 77955980762 scopus 로고    scopus 로고
    • Chronotherapy and the molecular clock: Clinical implications in oncology
    • Innominato PF, Levi FA, Bjarnason GA, (2010). Chronotherapy and the molecular clock: clinical implications in oncology. Adv Drug Deliv Rev 62: 979-1001.
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 979-1001
    • Innominato, P.F.1    Levi, F.A.2    Bjarnason, G.A.3
  • 19
    • 33746716146 scopus 로고    scopus 로고
    • Differential anti-proliferative actions of peroxisome proliferator-activated receptor-[gamma] agonists in MCF-7 breast cancer cells
    • Kim KY, Kim SS, Cheon HG, (2006). Differential anti-proliferative actions of peroxisome proliferator-activated receptor-[gamma] agonists in MCF-7 breast cancer cells. Biochem Pharmacol 72: 530-540.
    • (2006) Biochem Pharmacol , vol.72 , pp. 530-540
    • Kim, K.Y.1    Kim, S.S.2    Cheon, H.G.3
  • 21
    • 56549115139 scopus 로고    scopus 로고
    • Disruption of ERa signalling pathway by PPARy agonists: Evidences of PPARc-independent events in two hormonedependentbreast cancer cell lines
    • Lecomte J, Flament S, Salamone S, Boisbrun M, Mazerbourg S, Chapleur Y, et al. (2008). Disruption of ERa signalling pathway by PPAR y agonists: evidences of PPARc-independent events in two hormonedependentbreast cancer cell lines. Breast Cancer Res Treat 112: 437-451.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 437-451
    • Lecomte, J.1    Flament, S.2    Salamone, S.3    Boisbrun, M.4    Mazerbourg, S.5    Chapleur, Y.6
  • 22
    • 0041419231 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytes
    • Liang F, Wang F, Zhang S, Gardner DG, (2003). Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytes. Endocrinology 144: 4187-4194.
    • (2003) Endocrinology , vol.144 , pp. 4187-4194
    • Liang, F.1    Wang, F.2    Zhang, S.3    Gardner, D.G.4
  • 23
    • 1542349778 scopus 로고    scopus 로고
    • Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes
    • Lim CC, Zuppinger C, Guo X, Kuster GM, Helmes M, Eppenberger HM, et al. (2004). Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes. J Biol Chem 279: 8290-8299.
    • (2004) J Biol Chem , vol.279 , pp. 8290-8299
    • Lim, C.C.1    Zuppinger, C.2    Guo, X.3    Kuster, G.M.4    Helmes, M.5    Eppenberger, H.M.6
  • 24
    • 0037087687 scopus 로고    scopus 로고
    • Doxorubicin administration by continuous infusion is not cardioprotective: The Dana-Farber 91-01 Acute Lymphoblastic Leukemia protocol
    • Lipshultz SE, Giantris AL, Lipsitz SR, Kimball Dalton V, Asselin BL, Barr RD, et al. (2002). Doxorubicin administration by continuous infusion is not cardioprotective: the Dana-Farber 91-01 Acute Lymphoblastic Leukemia protocol. J Clin Oncol 20: 1677-1682.
    • (2002) J Clin Oncol , vol.20 , pp. 1677-1682
    • Lipshultz, S.E.1    Giantris, A.L.2    Lipsitz, S.R.3    Kimball Dalton, V.4    Asselin, B.L.5    Barr, R.D.6
  • 25
    • 34548660850 scopus 로고    scopus 로고
    • Mammalian circadian signaling networks and therapeutic targets
    • Liu AC, Lewis WG, Kay SA, (2007). Mammalian circadian signaling networks and therapeutic targets. Nat Chem Biol 3: 630-639.
    • (2007) Nat Chem Biol , vol.3 , pp. 630-639
    • Liu, A.C.1    Lewis, W.G.2    Kay, S.A.3
  • 26
    • 58549099485 scopus 로고    scopus 로고
    • Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways
    • Lyles BE, Akinyeke TO, Moss PE, Stewart LV, (2009). Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways. Cell Cycle 8: 268-277.
    • (2009) Cell Cycle , vol.8 , pp. 268-277
    • Lyles, B.E.1    Akinyeke, T.O.2    Moss, P.E.3    Stewart, L.V.4
  • 27
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L, (2004). Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 56: 185-229.
    • (2004) Pharmacol Rev , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 29
    • 29644448240 scopus 로고    scopus 로고
    • Prevention of doxorubicin-induced cardiotoxicity by melatonin
    • Oz E, Erbas D, Surucu HS, Duzgun E, (2006). Prevention of doxorubicin-induced cardiotoxicity by melatonin. Mol Cell Biochem 282: 31-37.
    • (2006) Mol Cell Biochem , vol.282 , pp. 31-37
    • Oz, E.1    Erbas, D.2    Surucu, H.S.3    Duzgun, E.4
  • 30
    • 79960699765 scopus 로고    scopus 로고
    • Effect of rosiglitazone on cardiac electrophysiology, infarct size and mitochondrial function in ischaemia and reperfusion of swine and rat heart
    • Palee S, Weerateerangkul P, Surinkeaw S, Chattipakorn S, Chattipakorn N, (2011a). Effect of rosiglitazone on cardiac electrophysiology, infarct size and mitochondrial function in ischaemia and reperfusion of swine and rat heart. Exp Physiol 96: 778-789.
    • (2011) Exp Physiol , vol.96 , pp. 778-789
    • Palee, S.1    Weerateerangkul, P.2    Surinkeaw, S.3    Chattipakorn, S.4    Chattipakorn, N.5
  • 31
    • 79960699765 scopus 로고    scopus 로고
    • Effect of rosiglitazone on cardiac electrophysiology, infarct size and mitochondrial function in ischaemia and reperfusion of swine and rat heart
    • Palee S, Weerateerangkul P, Surinkeaw S, Chattipakorn S, Chattipakorn N, (2011b). Effect of rosiglitazone on cardiac electrophysiology, infarct size and mitochondrial function in ischaemia and reperfusion of swine and rat heart. Exp Physiol 96: 778-789.
    • (2011) Exp Physiol , vol.96 , pp. 778-789
    • Palee, S.1    Weerateerangkul, P.2    Surinkeaw, S.3    Chattipakorn, S.4    Chattipakorn, N.5
  • 32
    • 68049121840 scopus 로고    scopus 로고
    • PPAR gamma protects cardiomyocytes against oxidative stress and apoptosis via Bcl-2 upregulation
    • Ren Y, Sun C, Sun Y, Tan H, Wu Y, Cui B, et al. (2009). PPAR gamma protects cardiomyocytes against oxidative stress and apoptosis via Bcl-2 upregulation. Vascul Pharmacol 51: 169-174.
    • (2009) Vascul Pharmacol , vol.51 , pp. 169-174
    • Ren, Y.1    Sun, C.2    Sun, Y.3    Tan, H.4    Wu, Y.5    Cui, B.6
  • 33
    • 80052853172 scopus 로고    scopus 로고
    • Results of a phase II trial of gemcitabine plus doxorubicin in patients with recurrent head and neck cancers: Serum C18-ceramide as a novel biomarker for monitoring response
    • Saddoughi SA, Garrett-Mayer E, Chaudhary U, O'Brien PE, Afrin LB, Day TA, et al. (2011). Results of a phase II trial of gemcitabine plus doxorubicin in patients with recurrent head and neck cancers: serum C18-ceramide as a novel biomarker for monitoring response. Clin Cancer Res 17: 6097-6105.
    • (2011) Clin Cancer Res , vol.17 , pp. 6097-6105
    • Saddoughi, S.A.1    Garrett-Mayer, E.2    Chaudhary, U.3    O'Brien, P.E.4    Afrin, L.B.5    Day, T.A.6
  • 34
    • 0037379266 scopus 로고    scopus 로고
    • Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition
    • Sahi J, Black C, Hamilton G, Zheng X, Jolley S, Rose K, et al. (2003). Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition. Drug Metab Dispos 31: 439-446.
    • (2003) Drug Metab Dispos , vol.31 , pp. 439-446
    • Sahi, J.1    Black, C.2    Hamilton, G.3    Zheng, X.4    Jolley, S.5    Rose, K.6
  • 35
    • 0033741281 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists
    • Sato H, Ishihara S, Kawashima K, Moriyama N, Suetsugu H, Kazumori H, et al. (2000). Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists. Br J Cancer 83: 1394-1400.
    • (2000) Br J Cancer , vol.83 , pp. 1394-1400
    • Sato, H.1    Ishihara, S.2    Kawashima, K.3    Moriyama, N.4    Suetsugu, H.5    Kazumori, H.6
  • 36
    • 77956249704 scopus 로고    scopus 로고
    • Rosiglitazone reverses cardiac adverse remodeling (fibrosis and vascularization) in perinatal low protein rat offspring
    • Torres TDS, Aguila MB, Mandarim-de-Lacerda CA, (2010). Rosiglitazone reverses cardiac adverse remodeling (fibrosis and vascularization) in perinatal low protein rat offspring. Pathol Res Pract 206: 642-646.
    • (2010) Pathol Res Pract , vol.206 , pp. 642-646
    • Torres, T.D.S.1    Aguila, M.B.2    Mandarim-De-Lacerda, C.A.3
  • 37
    • 0034643258 scopus 로고    scopus 로고
    • Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis
    • Tsubouchi Y, Sano H, Kawahito Y, Mukai S, Yamada R, Kohno M, et al. (2000). Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis. Biochem Biophys Res Commun 270: 400-405.
    • (2000) Biochem Biophys Res Commun , vol.270 , pp. 400-405
    • Tsubouchi, Y.1    Sano, H.2    Kawahito, Y.3    Mukai, S.4    Yamada, R.5    Kohno, M.6
  • 38
    • 33745113772 scopus 로고    scopus 로고
    • Beyond peroxisome proliferator-activated receptor gamma signaling: The multi-facets of the antitumor effect of thiazolidinediones
    • Weng JR, Chen CY, Pinzone JJ, Ringel MD, Chen CS, (2006). Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones. Endocr Relat Cancer 13: 401-413.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 401-413
    • Weng, J.R.1    Chen, C.Y.2    Pinzone, J.J.3    Ringel, M.D.4    Chen, C.S.5
  • 39
    • 6044274062 scopus 로고    scopus 로고
    • Cardiovascular complications of cancer therapy: Diagnosis, pathogenesis, and management
    • Yeh ET, Tong AT, Lenihan DJ, Yusuf SW, Swafford J, Champion C, et al. (2004). Cardiovascular complications of cancer therapy: diagnosis, pathogenesis, and management. Circulation 109: 3122-3131.
    • (2004) Circulation , vol.109 , pp. 3122-3131
    • Yeh, E.T.1    Tong, A.T.2    Lenihan, D.J.3    Yusuf, S.W.4    Swafford, J.5    Champion, C.6
  • 40
    • 84859844118 scopus 로고    scopus 로고
    • Circadian regulation of the hepatic endobiotic and xenobitoic detoxification pathways: The time matters
    • Zmrzljak UP, Rozman D, (2012). Circadian regulation of the hepatic endobiotic and xenobitoic detoxification pathways: the time matters. Chem Res Toxicol 25: 811-824.
    • (2012) Chem Res Toxicol , vol.25 , pp. 811-824
    • Zmrzljak, U.P.1    Rozman, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.