-
1
-
-
34247149015
-
The regulation of cyclin D1 degradation: Roles in cancer development and the potential for therapeutic invention
-
Alao JP, (2007). The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention. Mol Cancer 6: 24.
-
(2007)
Mol Cancer
, vol.6
, pp. 24
-
-
Alao, J.P.1
-
2
-
-
18144388677
-
Selective activation of PPARgamma in breast, colon, and lung cancer cell lines
-
Allred CD, Kilgore MW, (2005). Selective activation of PPARgamma in breast, colon, and lung cancer cell lines. Mol Cell Endocrinol 235: 21-29.
-
(2005)
Mol Cell Endocrinol
, vol.235
, pp. 21-29
-
-
Allred, C.D.1
Kilgore, M.W.2
-
3
-
-
34247151073
-
Melatonin: Therapeutic and clinical utilization
-
Altun A, Ugur-Altun B, (2007). Melatonin: therapeutic and clinical utilization. Int J Clin Pract 61: 835-845.
-
(2007)
Int J Clin Pract
, vol.61
, pp. 835-845
-
-
Altun, A.1
Ugur-Altun, B.2
-
4
-
-
0034085810
-
Acute doxorubicin cardiotoxicity involves cardiomyocyte apoptosis
-
Arola OJ, Saraste A, Pulkki K, Kallajoki M, Parvinen M, Voipio-Pulkki LM, (2000). Acute doxorubicin cardiotoxicity involves cardiomyocyte apoptosis. Cancer Res 60: 1789-1792.
-
(2000)
Cancer Res
, vol.60
, pp. 1789-1792
-
-
Arola, O.J.1
Saraste, A.2
Pulkki, K.3
Kallajoki, M.4
Parvinen, M.5
Voipio-Pulkki, L.M.6
-
5
-
-
0038339692
-
Inhibition of fibroblast proliferation in cardiac myocyte cultures by surface microtopography
-
Boateng SY, Hartman TJ, Ahluwalia N, Vidula H, Desai TA, Russell B, (2003). Inhibition of fibroblast proliferation in cardiac myocyte cultures by surface microtopography. Am J Physiol Cell Physiol 285: C171-C182.
-
(2003)
Am J Physiol Cell Physiol
, vol.285
-
-
Boateng, S.Y.1
Hartman, T.J.2
Ahluwalia, N.3
Vidula, H.4
Desai, T.A.5
Russell, B.6
-
6
-
-
11144346203
-
Structural and functional characterisation of cardiac fibroblasts
-
Camelliti P, Borg TK, Kohl P, (2005). Structural and functional characterisation of cardiac fibroblasts. Cardiovasc Res 65: 40-51.
-
(2005)
Cardiovasc Res
, vol.65
, pp. 40-51
-
-
Camelliti, P.1
Borg, T.K.2
Kohl, P.3
-
7
-
-
84857055427
-
First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: A phase I/II open-label and double-blind study
-
Demetri G, Le Cesne A, Chawla S, Brodowicz T, Maki RG, Bach B, et al.(2012). First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: a phase I/II open-label and double-blind study. Eur J Cancer 48: 547-563.
-
(2012)
Eur J Cancer
, vol.48
, pp. 547-563
-
-
Demetri, G.1
Le Cesne, A.2
Chawla, S.3
Brodowicz, T.4
Maki, R.G.5
Bach, B.6
-
8
-
-
77950838898
-
Melatonin and doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines
-
Fan LL, Sun GP, Wei W, Wang ZG, Ge L, Fu WZ, et al. (2010). Melatonin and doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines. World J Gastroenterol 16: 1473-1481.
-
(2010)
World J Gastroenterol
, vol.16
, pp. 1473-1481
-
-
Fan, L.L.1
Sun, G.P.2
Wei, W.3
Wang, Z.G.4
Ge, L.5
Fu, W.Z.6
-
9
-
-
80052032897
-
Single-agent pegylated liposomal doxorubicin (PLD) in the treatment of metastatic breast cancer: Results of an Austrian observational trial
-
Fiegl M, Mlineritsch B, Hubalek M, Bartsch R, Pluschnig U, Steger GG, (2011). Single-agent pegylated liposomal doxorubicin (PLD) in the treatment of metastatic breast cancer: results of an Austrian observational trial. BMC Cancer 11: 373.
-
(2011)
BMC Cancer
, vol.11
, pp. 373
-
-
Fiegl, M.1
Mlineritsch, B.2
Hubalek, M.3
Bartsch, R.4
Pluschnig, U.5
Steger, G.G.6
-
10
-
-
0035099803
-
Ternary combination of irinotecan, fluorouracil-folinic acid and oxaliplatin: Results on human colon cancer cell lines
-
Fischel JL, Rostagno P, Formento P, Dubreuil A, Etienne MC, Milano G, (2001). Ternary combination of irinotecan, fluorouracil-folinic acid and oxaliplatin: results on human colon cancer cell lines. Br J Cancer 84: 579-585.
-
(2001)
Br J Cancer
, vol.84
, pp. 579-585
-
-
Fischel, J.L.1
Rostagno, P.2
Formento, P.3
Dubreuil, A.4
Etienne, M.C.5
Milano, G.6
-
11
-
-
0029936580
-
Growth arrest and non-apoptotic cell death associated with the suppression of c-myc expression in MCF-7 breast tumor cells following acute exposure to doxorubicin
-
Fornari FA, Jarvis W, Grant S, Orr MS, Randolph JK, White FKH, et al. (1996). Growth arrest and non-apoptotic cell death associated with the suppression of c-myc expression in MCF-7 breast tumor cells following acute exposure to doxorubicin. Biochem Pharmacol 51: 931-940.
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 931-940
-
-
Fornari, F.A.1
Jarvis, W.2
Grant, S.3
Orr, M.S.4
Randolph, J.K.5
White, F.K.H.6
-
12
-
-
0032032987
-
Melatonin enhances tamoxifen's ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation
-
García J, Reiter R, Ortiz G, Oh C, Tang L, Yu B, et al. (1998). Melatonin enhances tamoxifen's ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation. J Membr Biol 162: 59-65.
-
(1998)
J Membr Biol
, vol.162
, pp. 59-65
-
-
García, J.1
Reiter, R.2
Ortiz, G.3
Oh, C.4
Tang, L.5
Yu, B.6
-
13
-
-
0033006172
-
A critical evaluation of the mechanisms of action proposed for the antitumor effects of thenthracycline antibiotics adriamycin and daunorubicin
-
Gewirtz D, (1999). A critical evaluation of the mechanisms of action proposed for the antitumor effects of thenthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 57: 727-741.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 727-741
-
-
Gewirtz, D.1
-
14
-
-
0035266333
-
Experimental chronotherapy of mouse mammary adenocarcinoma MA13/C with docetaxel and doxorubicin as single agents and in combination
-
Granda TG, Filipski E, D'Attino RM, Vrignaud P, Anjo A, Bissery MC, et al. (2001). Experimental chronotherapy of mouse mammary adenocarcinoma MA13/C with docetaxel and doxorubicin as single agents and in combination. Cancer Res 61: 1996-2001.
-
(2001)
Cancer Res
, vol.61
, pp. 1996-2001
-
-
Granda, T.G.1
Filipski, E.2
D'Attino, R.M.3
Vrignaud, P.4
Anjo, A.5
Bissery, M.C.6
-
15
-
-
33846549188
-
Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells
-
Greco F, Vicent MJ, Gee S, Jones AT, Gee J, Nicholson RI, et al. (2007). Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells. J Control Release 117: 28-39.
-
(2007)
J Control Release
, vol.117
, pp. 28-39
-
-
Greco, F.1
Vicent, M.J.2
Gee, S.3
Jones, A.T.4
Gee, J.5
Nicholson, R.I.6
-
16
-
-
67649236122
-
Melatonin: Signaling mechanisms of a pleiotropic agent
-
Hardeland R, (2009). Melatonin: signaling mechanisms of a pleiotropic agent. Biofactors 35: 183-192.
-
(2009)
Biofactors
, vol.35
, pp. 183-192
-
-
Hardeland, R.1
-
17
-
-
37548999000
-
Rosiglitazone treatment improves cardiac efficiency in hearts from diabetic mice
-
How OJ, Larsen TS, Hafstad AD, Khalid A, Myhre ES, Murray AJ, et al. (2007). Rosiglitazone treatment improves cardiac efficiency in hearts from diabetic mice. Arch Physiol Biochem 113: 211-220.
-
(2007)
Arch Physiol Biochem
, vol.113
, pp. 211-220
-
-
How, O.J.1
Larsen, T.S.2
Hafstad, A.D.3
Khalid, A.4
Myhre, E.S.5
Murray, A.J.6
-
18
-
-
77955980762
-
Chronotherapy and the molecular clock: Clinical implications in oncology
-
Innominato PF, Levi FA, Bjarnason GA, (2010). Chronotherapy and the molecular clock: clinical implications in oncology. Adv Drug Deliv Rev 62: 979-1001.
-
(2010)
Adv Drug Deliv Rev
, vol.62
, pp. 979-1001
-
-
Innominato, P.F.1
Levi, F.A.2
Bjarnason, G.A.3
-
19
-
-
33746716146
-
Differential anti-proliferative actions of peroxisome proliferator-activated receptor-[gamma] agonists in MCF-7 breast cancer cells
-
Kim KY, Kim SS, Cheon HG, (2006). Differential anti-proliferative actions of peroxisome proliferator-activated receptor-[gamma] agonists in MCF-7 breast cancer cells. Biochem Pharmacol 72: 530-540.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 530-540
-
-
Kim, K.Y.1
Kim, S.S.2
Cheon, H.G.3
-
20
-
-
0037453585
-
Myocytes die by multiple mechanisms in failing human hearts
-
Kostin S, Pool L, Elsasser A, Hein S, Drexler HC, Arnon E, et al. (2003). Myocytes die by multiple mechanisms in failing human hearts. Circ Res 92: 715-724.
-
(2003)
Circ Res
, vol.92
, pp. 715-724
-
-
Kostin, S.1
Pool, L.2
Elsasser, A.3
Hein, S.4
Drexler, H.C.5
Arnon, E.6
-
21
-
-
56549115139
-
Disruption of ERa signalling pathway by PPARy agonists: Evidences of PPARc-independent events in two hormonedependentbreast cancer cell lines
-
Lecomte J, Flament S, Salamone S, Boisbrun M, Mazerbourg S, Chapleur Y, et al. (2008). Disruption of ERa signalling pathway by PPAR y agonists: evidences of PPARc-independent events in two hormonedependentbreast cancer cell lines. Breast Cancer Res Treat 112: 437-451.
-
(2008)
Breast Cancer Res Treat
, vol.112
, pp. 437-451
-
-
Lecomte, J.1
Flament, S.2
Salamone, S.3
Boisbrun, M.4
Mazerbourg, S.5
Chapleur, Y.6
-
22
-
-
0041419231
-
Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytes
-
Liang F, Wang F, Zhang S, Gardner DG, (2003). Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytes. Endocrinology 144: 4187-4194.
-
(2003)
Endocrinology
, vol.144
, pp. 4187-4194
-
-
Liang, F.1
Wang, F.2
Zhang, S.3
Gardner, D.G.4
-
23
-
-
1542349778
-
Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes
-
Lim CC, Zuppinger C, Guo X, Kuster GM, Helmes M, Eppenberger HM, et al. (2004). Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes. J Biol Chem 279: 8290-8299.
-
(2004)
J Biol Chem
, vol.279
, pp. 8290-8299
-
-
Lim, C.C.1
Zuppinger, C.2
Guo, X.3
Kuster, G.M.4
Helmes, M.5
Eppenberger, H.M.6
-
24
-
-
0037087687
-
Doxorubicin administration by continuous infusion is not cardioprotective: The Dana-Farber 91-01 Acute Lymphoblastic Leukemia protocol
-
Lipshultz SE, Giantris AL, Lipsitz SR, Kimball Dalton V, Asselin BL, Barr RD, et al. (2002). Doxorubicin administration by continuous infusion is not cardioprotective: the Dana-Farber 91-01 Acute Lymphoblastic Leukemia protocol. J Clin Oncol 20: 1677-1682.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1677-1682
-
-
Lipshultz, S.E.1
Giantris, A.L.2
Lipsitz, S.R.3
Kimball Dalton, V.4
Asselin, B.L.5
Barr, R.D.6
-
25
-
-
34548660850
-
Mammalian circadian signaling networks and therapeutic targets
-
Liu AC, Lewis WG, Kay SA, (2007). Mammalian circadian signaling networks and therapeutic targets. Nat Chem Biol 3: 630-639.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 630-639
-
-
Liu, A.C.1
Lewis, W.G.2
Kay, S.A.3
-
26
-
-
58549099485
-
Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways
-
Lyles BE, Akinyeke TO, Moss PE, Stewart LV, (2009). Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways. Cell Cycle 8: 268-277.
-
(2009)
Cell Cycle
, vol.8
, pp. 268-277
-
-
Lyles, B.E.1
Akinyeke, T.O.2
Moss, P.E.3
Stewart, L.V.4
-
27
-
-
2642566088
-
Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
-
Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L, (2004). Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 56: 185-229.
-
(2004)
Pharmacol Rev
, vol.56
, pp. 185-229
-
-
Minotti, G.1
Menna, P.2
Salvatorelli, E.3
Cairo, G.4
Gianni, L.5
-
28
-
-
79960130488
-
Molecular basis of chronopharmaceutics
-
Ohdo S, Koyanagi S, Matsunaga N, Hamdan A, (2011). Molecular basis of chronopharmaceutics. J Pharm Sci 100: 3560-3576.
-
(2011)
J Pharm Sci
, vol.100
, pp. 3560-3576
-
-
Ohdo, S.1
Koyanagi, S.2
Matsunaga, N.3
Hamdan, A.4
-
29
-
-
29644448240
-
Prevention of doxorubicin-induced cardiotoxicity by melatonin
-
Oz E, Erbas D, Surucu HS, Duzgun E, (2006). Prevention of doxorubicin-induced cardiotoxicity by melatonin. Mol Cell Biochem 282: 31-37.
-
(2006)
Mol Cell Biochem
, vol.282
, pp. 31-37
-
-
Oz, E.1
Erbas, D.2
Surucu, H.S.3
Duzgun, E.4
-
30
-
-
79960699765
-
Effect of rosiglitazone on cardiac electrophysiology, infarct size and mitochondrial function in ischaemia and reperfusion of swine and rat heart
-
Palee S, Weerateerangkul P, Surinkeaw S, Chattipakorn S, Chattipakorn N, (2011a). Effect of rosiglitazone on cardiac electrophysiology, infarct size and mitochondrial function in ischaemia and reperfusion of swine and rat heart. Exp Physiol 96: 778-789.
-
(2011)
Exp Physiol
, vol.96
, pp. 778-789
-
-
Palee, S.1
Weerateerangkul, P.2
Surinkeaw, S.3
Chattipakorn, S.4
Chattipakorn, N.5
-
31
-
-
79960699765
-
Effect of rosiglitazone on cardiac electrophysiology, infarct size and mitochondrial function in ischaemia and reperfusion of swine and rat heart
-
Palee S, Weerateerangkul P, Surinkeaw S, Chattipakorn S, Chattipakorn N, (2011b). Effect of rosiglitazone on cardiac electrophysiology, infarct size and mitochondrial function in ischaemia and reperfusion of swine and rat heart. Exp Physiol 96: 778-789.
-
(2011)
Exp Physiol
, vol.96
, pp. 778-789
-
-
Palee, S.1
Weerateerangkul, P.2
Surinkeaw, S.3
Chattipakorn, S.4
Chattipakorn, N.5
-
32
-
-
68049121840
-
PPAR gamma protects cardiomyocytes against oxidative stress and apoptosis via Bcl-2 upregulation
-
Ren Y, Sun C, Sun Y, Tan H, Wu Y, Cui B, et al. (2009). PPAR gamma protects cardiomyocytes against oxidative stress and apoptosis via Bcl-2 upregulation. Vascul Pharmacol 51: 169-174.
-
(2009)
Vascul Pharmacol
, vol.51
, pp. 169-174
-
-
Ren, Y.1
Sun, C.2
Sun, Y.3
Tan, H.4
Wu, Y.5
Cui, B.6
-
33
-
-
80052853172
-
Results of a phase II trial of gemcitabine plus doxorubicin in patients with recurrent head and neck cancers: Serum C18-ceramide as a novel biomarker for monitoring response
-
Saddoughi SA, Garrett-Mayer E, Chaudhary U, O'Brien PE, Afrin LB, Day TA, et al. (2011). Results of a phase II trial of gemcitabine plus doxorubicin in patients with recurrent head and neck cancers: serum C18-ceramide as a novel biomarker for monitoring response. Clin Cancer Res 17: 6097-6105.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6097-6105
-
-
Saddoughi, S.A.1
Garrett-Mayer, E.2
Chaudhary, U.3
O'Brien, P.E.4
Afrin, L.B.5
Day, T.A.6
-
34
-
-
0037379266
-
Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition
-
Sahi J, Black C, Hamilton G, Zheng X, Jolley S, Rose K, et al. (2003). Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition. Drug Metab Dispos 31: 439-446.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 439-446
-
-
Sahi, J.1
Black, C.2
Hamilton, G.3
Zheng, X.4
Jolley, S.5
Rose, K.6
-
35
-
-
0033741281
-
Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists
-
Sato H, Ishihara S, Kawashima K, Moriyama N, Suetsugu H, Kazumori H, et al. (2000). Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists. Br J Cancer 83: 1394-1400.
-
(2000)
Br J Cancer
, vol.83
, pp. 1394-1400
-
-
Sato, H.1
Ishihara, S.2
Kawashima, K.3
Moriyama, N.4
Suetsugu, H.5
Kazumori, H.6
-
36
-
-
77956249704
-
Rosiglitazone reverses cardiac adverse remodeling (fibrosis and vascularization) in perinatal low protein rat offspring
-
Torres TDS, Aguila MB, Mandarim-de-Lacerda CA, (2010). Rosiglitazone reverses cardiac adverse remodeling (fibrosis and vascularization) in perinatal low protein rat offspring. Pathol Res Pract 206: 642-646.
-
(2010)
Pathol Res Pract
, vol.206
, pp. 642-646
-
-
Torres, T.D.S.1
Aguila, M.B.2
Mandarim-De-Lacerda, C.A.3
-
37
-
-
0034643258
-
Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis
-
Tsubouchi Y, Sano H, Kawahito Y, Mukai S, Yamada R, Kohno M, et al. (2000). Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis. Biochem Biophys Res Commun 270: 400-405.
-
(2000)
Biochem Biophys Res Commun
, vol.270
, pp. 400-405
-
-
Tsubouchi, Y.1
Sano, H.2
Kawahito, Y.3
Mukai, S.4
Yamada, R.5
Kohno, M.6
-
38
-
-
33745113772
-
Beyond peroxisome proliferator-activated receptor gamma signaling: The multi-facets of the antitumor effect of thiazolidinediones
-
Weng JR, Chen CY, Pinzone JJ, Ringel MD, Chen CS, (2006). Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones. Endocr Relat Cancer 13: 401-413.
-
(2006)
Endocr Relat Cancer
, vol.13
, pp. 401-413
-
-
Weng, J.R.1
Chen, C.Y.2
Pinzone, J.J.3
Ringel, M.D.4
Chen, C.S.5
-
39
-
-
6044274062
-
Cardiovascular complications of cancer therapy: Diagnosis, pathogenesis, and management
-
Yeh ET, Tong AT, Lenihan DJ, Yusuf SW, Swafford J, Champion C, et al. (2004). Cardiovascular complications of cancer therapy: diagnosis, pathogenesis, and management. Circulation 109: 3122-3131.
-
(2004)
Circulation
, vol.109
, pp. 3122-3131
-
-
Yeh, E.T.1
Tong, A.T.2
Lenihan, D.J.3
Yusuf, S.W.4
Swafford, J.5
Champion, C.6
-
40
-
-
84859844118
-
Circadian regulation of the hepatic endobiotic and xenobitoic detoxification pathways: The time matters
-
Zmrzljak UP, Rozman D, (2012). Circadian regulation of the hepatic endobiotic and xenobitoic detoxification pathways: the time matters. Chem Res Toxicol 25: 811-824.
-
(2012)
Chem Res Toxicol
, vol.25
, pp. 811-824
-
-
Zmrzljak, U.P.1
Rozman, D.2
|