Rimonabant dimorphism and its pressure-temperature phase diagram: A delicate case of overall monotropic behavior

Journal of Pharmaceutical Sciences

Volumn 102, Issue 7, 2013, Pages 2311-2321

  Perrin, Marc Antoine ^a   Bauer, Michel ^a   Barrio, Maria ^b   Tamarit, Josep Lluís ^b   Céolin, René ^b,c   Rietveld, Ivo B ^c  

^a SANOFI   (France)

^b UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

API; Clapeyron equation; Crystal structure; High pressure; Polymorphism; Stability; Thermal analysis; Thermodynamics; Topological phase diagram

Indexed keywords

RIMONABANT;

ARTICLE; CRYSTALLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENTHALPY; HYDROGEN BOND; MELTING POINT; PRESSURE; SOLID STATE; TEMPERATURE; THERMAL ANALYSIS; VAPOR PRESSURE;

EID: 84879005796     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23612     Document Type: Article

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