Simultaneous determination of 9-dehydro-17-hydro-andrographolide and sodium 9-dehydro-17-hydro-andrographolide-19-yl sulfate in rat plasma by UHPLC-ESI-MS/MS after administration of xiyanping injection: Application to a pharmacokinetic study

Biomedical Chromatography

Volumn 27, Issue 7, 2013, Pages 825-830

  Chong, Lan ^a,b   Chen, Weikang ^a   Luo, Yuehua ^a,b   Jiang, Zihua ^c  

^a Jiangxi Provincial Institute for Drug and Food Control   (China)

^b NANCHANG UNIVERSITY   (China)

^c LAKEHEAD UNIVERSITY   (Canada)

Author keywords

9 dehydro 17 hydro andrographolide; Pharmacokinetics; Sodium 9 dehydro 17 hydro andrographolide 19 yl sulfate; UHPLC ESI MS MS; Xiyanping injection

Indexed keywords

BODY FLUIDS; NEGATIVE IONS; RATS; SODIUM; SULFUR COMPOUNDS;

9-DEHYDRO-17-HYDRO-ANDROGRAPHOLIDE; ANDROGRAPHOLIDE; INTERNAL STANDARDS; PHARMACOKINETIC STUDIES; RAT PLASMA; SODIUM 9-DEHYDRO-17-HYDRO-ANDROGRAPHOLIDE-19-YL SULPHATE; SULPHATES; UHPLC-ESI MS=MS; XIYANPING INJECTION;

PHARMACOKINETICS;

9 DEHYDRO 17 HYDRO ANDROGRAPHOLIDE; ANDROGRAPHOLIDE; METHANOL; SODIUM 9 DEHYDRO 17 HYDRO ANDROGRAPHOLIDE 19 YL SULFATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; NONHUMAN; RAT; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

RATTUS;

EID: 84878995480     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2866     Document Type: Article

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