Disrupted prenatal maternal cortisol, maternal obesity, and childhood wheeze: Insights into prenatal programming

American Journal of Respiratory and Critical Care Medicine

Volumn 187, Issue 11, 2013, Pages 1186-1193

  Wright, Rosalind J ^a   Fisher, Kate ^b   Chiu, Yueh Hsiu Mathilda ^a   Wright, Robert O ^a   Fein, Rebecca ^c   Cohen, Sheldon ^d   Coull, Brent A ^e  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d CARNEGIE MELLON UNIVERSITY   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Childhood wheeze; Maternal cortisol; Obesity; Prenatal programming

Indexed keywords

HYDROCORTISONE;

ADULT; AFRICAN AMERICAN; ARTICLE; BODY MASS; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; EDUCATIONAL STATUS; FEMALE; GESTATIONAL AGE; GROUPS BY AGE; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MALE; MATERNAL OBESITY; PRESCHOOL CHILD; PRIORITY JOURNAL; SALIVA ANALYSIS; WHEEZING;

BODY MASS INDEX; FEMALE; HUMANS; HYDROCORTISONE; INCIDENCE; MATERNAL EXPOSURE; OBESITY; PREGNANCY; PRENATAL CARE; PRENATAL EXPOSURE DELAYED EFFECTS; PROSPECTIVE STUDIES; RESPIRATORY SOUNDS; RISK FACTORS; SALIVA; UNITED STATES;

EID: 84878991493     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201208-1530OC     Document Type: Article

References (58)

1. Mathilda Chiu YH, Coull BA, Cohen S, Wooley A, Wright RJ. Prenatal and postnatal maternal stress and wheeze in urban children: effect of maternal sensitization. Am J Respir Crit Care Med 2012;186:147-154.
2. Cookson H, Granell R, Joinson C, Ben-Shlomo Y, Henderson AJ. Mothers' anxiety during pregnancy is associated with asthma in their children. J Allergy Clin Immunol 2009;123:847-853, e11.
3. Reyes M, Perzanowski MS, Whyatt RM, Kelvin EA, Rundle AG, Diaz DM, Hoepner L, Perera FP, Rauh V, Miller RL. Relationship between maternal demoralization, wheeze, and immunoglobulin E among innercity children. Ann Allergy Asthma Immunol 2011;107:42-49, e1.
4. Harris A, Seckl J. Glucocorticoids, prenatal stress and the programming of disease. Horm Behav 2011;59:279-289.
5. Wright RJ. Prenatal maternal stress and early caregiving experiences: implications for childhood asthma risk. Paediatr Perinat Epidemiol 2007;21:8-14. (Pubitemid 47568803)
6. Wright RJ. Perinatal stress and early life programming of lung structure and function. Biol Psychol 2010;84:46-56.
7. Rondó PH, Lemos JO, Pereira JA, Souza JM. The relationship between cortisol concentrations in pregnancy and systemic vascular resistance in childhood. Early Hum Dev 2010;86:127-131.
8. Bolten MI, Wurmser H, Buske-Kirschbaum A, Papoušek M, Pirke KM, Hellhammer D. Cortisol levels in pregnancy as a psychobiological predictor for birth weight. Arch Women Ment Health 2011;14:33-41.
9. LeWinn KZ, Stroud LR, Molnar BE, Ware JH, Koenen KC, Buka SL. Elevated maternal cortisol levels during pregnancy are associated with reduced childhood IQ. Int J Epidemiol 2009;38:1700-1710.
10. Beijers R, Jansen J, Riksen-Walraven M, de Weerth C. Maternal prenatal anxiety and stress predict infant illnesses and health complaints. Pediatrics 2010;126:e401-e409.
11. Håberg SE, Stigum H, London SJ, Nystad W, Nafstad P. Maternal obesity in pregnancy and respiratory health in early childhood. Paediatr Perinat Epidemiol 2009;23:352-362.
12. Reichman NE, Nepomnyaschy L. Maternal pre-pregnancy obesity and diagnosis of asthma in offspring at age 3 years. Matern Child Health J 2008;12:725-733.
13. Scholtens S, Wijga AH, Brunekreef B, Kerkhof M, Postma DS, Oldenwening M, de Jongste JC, Smit HA. Maternal overweight before pregnancy and asthma in offspring followed for 8 years. Int J Obes (Lond) 2010;34:606-613.
14. Lowe A, Bråbäck L, Ekeus C, Hjern A, Forsberg B. Maternal obesity during pregnancy as a risk for early-life asthma. J Allergy Clin Immunol 2011;128:1107-1109.e1-e2.
15. Weiss ST. Obesity: insight into the origins of asthma. Nat Immunol 2005;6:537-539. (Pubitemid 41710719)
16. Müssig K, Remer T, Maser-Gluth C. Brief review: glucocorticoid excretion in obesity. J Steroid Biochem Mol Biol 2010;121:589-593.
17. Larsson CA, Gullberg B, Råstam L, Lindblad U. Salivary cortisol differs with age and sex and shows inverse associations with WHR in Swedish women: a cross-sectional study. BMC Endocr Disord 2009;9:16.
18. Kumari M, Chandola T, Brunner E, Kivimaki M. A nonlinear relationship of generalized and central obesity with diurnal cortisol secretion in the Whitehall II study. J Clin Endocrinol Metab 2010;95:4415-4423.
19. Stewart FM, Freeman DJ, Ramsay JE, Greer IA, Caslake M, Ferrell WR. Longitudinal assessment of maternal endothelial function and markers of inflammation and placental function throughout pregnancy in lean and obese mothers. J Clin Endocrinol Metab 2007;92:969-975. (Pubitemid 46465671)
20. Challier JC, Basu S, Bintein T, Minium J, Hotmire K, Catalano PM, Hauguelde Mouzon S. Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placenta. Placenta 2008;29:274-281.
21. Heerwagen MJ, Miller MR, Barbour LA, Friedman JE. Maternal obesity and fetal metabolic programming: a fertile epigenetic soil. Am J Physiol Regul Integr Comp Physiol 2010;299:R711-R722.
22. Shore SA. Obesity and asthma: possible mechanisms. J Allergy Clin Immunol 2008;121:1087-1093; quiz 1094-1085.
23. Shore SA. Obesity and asthma: lessons from animal models. J Appl Physiol 2007;102:516-528. (Pubitemid 46220879)
24. Hersoug LG, Linneberg A. The link between the epidemics of obesity and allergic diseases: does obesity induce decreased immune tolerance? Allergy 2007;62:1205-1213. (Pubitemid 47374032)
25. Balistreri CR, Caruso C, Candore G. The role of adipose tissue and adipokines in obesity-related inflammatory diseases. Mediators Inflamm 2010;2010:802078.
26. Lugogo NL, Kraft M, Dixon AE. Does obesity produce a distinct asthma phenotype? J Appl Physiol 2010;108:729-734.
27. Wright RJ, Fisher K, Chiu Y-HM, Cohen S, Coull B. Disruption of maternal diurnal cortisol in pregnancy and prenatal BMI are associated with repeated wheeze up to age 2.5 years in urban children: Project ACCESS. Presented at the American Thoracic Society 2011 International Conference. May 13-18, 2011, Denver, CO.
28. Wright RJ, Enlow MB. Maternal stress and perinatal programming in the expression of atopy. Expert Rev Clin Immunol 2008;4:535-538.
29. Kivlighan KT, DiPietro JA, Costigan KA, Laudenslager ML. Diurnal rhythm of cortisol during late pregnancy: associations with maternal psychological well-being and fetal growth. Psychoneuroendocrinology 2008;33:1225-1235.
30. Adam EK, Kumari M. Assessing salivary cortisol in large-scale, epidemiological research. Psychoneuroendocrinology 2009;34:1423-1436.
31. Kirschbaum C, Hellhammer DH. Salivary cortisol in psychoneuroendocrine research: recent developments and applications. Psychoneuroendocrinology 1994;19:313-333. (Pubitemid 24150545)
32. Strazdins L, Meyerkort S, Brent V, D'Souza RM, Broom DH, Kyd JM. Impact of saliva collection methods on sIgA and cortisol assays and acceptability to participants. J Immunol Methods 2005;307:167-171. (Pubitemid 41817277)
33. Gold DR, Burge HA, Carey V, Milton DK, Platts-Mills T, Weiss ST. Predictors of repeated wheeze in the first year of life: the relative roles of cockroach, birth weight, acute lower respiratory illness, and maternal smoking. Am J Respir Crit Care Med 1999;160:227-236. (Pubitemid 29326093)
34. World Health Organization. BMI classification [accessed 2013 May 19]. Available from: http://apps.who.int/bmi/index.jsp?introPage=intro-3.html
35. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1:307-310. (Pubitemid 16134762)
36. Glynn LM, Schetter CD, Chicz-DeMet A, Hobel CJ, Sandman CA. Ethnic differences in adrenocorticotropic hormone, cortisol and corticotropin-releasing hormone during pregnancy. Peptides 2007;28:1155-1161. (Pubitemid 46843390)
37. Polk DE, Cohen S, Doyle WJ, Skoner DP, Kirschbaum C. State and trait affect as predictors of salivary cortisol in healthy adults. Psychoneuroendocrinology 2005;30:261-272. (Pubitemid 39423360)
38. Cohen S, Schwartz JE, Epel E, Kirschbaum C, Sidney S, Seeman T. Socioeconomic status, race, and diurnal cortisol decline in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Psychosom Med 2006;68:41-50. (Pubitemid 43803214)
39. Oken E, Kleinman KP, Rich-Edwards J, Gillman MW. A nearly continuous measure of birth weight for gestational age using a United States national reference. BMC Pediatr 2003;3:6.
40. Arck PC, Knackstedt MK, Blois SM. Current insights and future perspectives on neuro-endocrine-immune circuitry challenging pregnancy maintenance and fetal health. J Reproduktionsmed Endokrinol 2006;3:98-102. (Pubitemid 43855571)
41. Bolt RJ, van Weissenbruch MM, Lafeber HN, Delemarre-van de Waal HA. Glucocorticoids and lung development in the fetus and preterm infant. Pediatr Pulmonol 2001;32:76-91.
42. von Hertzen LC. Maternal stress and T-cell differentiation of the developing immune system: possible implications for the development of asthma and atopy. J Allergy Clin Immunol 2002;109:923-928.
43. Elenkov IJ, Iezzoni DG, Daly A, Harris AG, Chrousos GP. Cytokine dysregulation, inflammation and well-being. Neuroimmunomodulation 2005;12:255-269. (Pubitemid 41318209)
44. Jansson T, Powell TL. Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches. Clin Sci (Lond) 2007;113:1-13. (Pubitemid 47066020)
45. Wright RJ. Stress-related programming of autonomic imbalance: role in allergy and asthma. Chem Immunol Allergy 2012;98:32-47.
46. Young JB. Programming of sympathoadrenal function. Trends Endocrinol Metab 2002;13:381-385. (Pubitemid 36723590)
47. Eskandari F, Webster JI, Sternberg EM. Neural immune pathways and their connection to inflammatory diseases. Arthritis Res Ther 2003;5:251-265. (Pubitemid 37407974)
48. Raison CL, Miller AH. When not enough is too much: the role of insufficient gluccocorticoid signaling in the pathophysiology of stress-related disorders. Am J Psychiatry 2003;160:1554-1565. (Pubitemid 41079539)
49. Guerra S, Martinez FD. Epidemiology of the origins of airflow limitation in asthma. Proc Am Thorac Soc 2009;6:707-711.
50. Duclos M, Corcuff JB, Etcheverry N, Rashedi M, Tabarin A, Roger P. Abdominal obesity increases overnight cortisol excretion. J Endocrinol Invest 1999;22:465-471. (Pubitemid 29355564)
51. Farag NH, Moore WE, Lovallo WR, Mills PJ, Khandrika S, Eichner JE. Hypothalamic-pituitary-adrenal axis function: relative contributions of perceived stress and obesity in women. J Womens Health (Larchmt) 2008;17:1647-1655.
52. Davy KP, Orr JS. Sympathetic nervous system behavior in human obesity. Neurosci Biobehav Rev 2009;33:116-124.
53. Helmreich RJ, Hundley V, Varvel P. The effect of obesity on heart rate (heart period) and physiologic parameters during pregnancy. Biol Res Nurs 2008;10:63-78.
54. Staab CA, Maser E. 11beta-Hydroxysteroid dehydrogenase type 1 is an important regulator at the interface of obesity and inflammation. J Steroid Biochem Mol Biol 2010;119:56-72.
55. Wright RJ, Cohen S, Carey V, Weiss ST, Gold DR. Parental stress as a predictor of wheezing in infancy: a prospective birth-cohort study. Am J Respir Crit Care Med 2002;165:358-365. (Pubitemid 34118509)
56. Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010;303:235-241.
57. Davis EM, Stange KC, Horwitz RI. Childbearing, stress and obesity disparities in women: a public health perspective. Matern Child Health J 2012;16:109-118.
58. Suglia SF, Staudenmayer J, Cohen S, Enlow MB, Rich-Edwards JW, Wright RJ. Cumulative stress and cortisol disruption among black and Hispanic pregnant women in an urban cohort. Psychol Trauma 2010;2:326-334. Stress Stress Stress