Neurodegenerative disease: Frontotemporal dementia - Time to target inflammation?

Nature Reviews Neurology

Volumn 9, Issue 6, 2013, Pages 304-305

  Piguet, Olivier ^a  

^a NEUROSCIENCE RESEARCH AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROGRANULIN; TAR DNA BINDING PROTEIN; TUMOR NECROSIS FACTOR;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; AUTOIMMUNE DISEASE; BEHAVIOR DISORDER; CEREBROSPINAL FLUID EXAMINATION; DEMENTIA; DISEASE ASSOCIATION; FRONTAL VARIANT FRONTOTEMPORAL DEMENTIA; FRONTOTEMPORAL DEMENTIA; HISTOPATHOLOGY; HUMAN; INFLAMMATION; LANGUAGE DISABILITY; NERVOUS SYSTEM INFLAMMATION; PREVALENCE; PRIMARY PROGRESSIVE APHASIA; PRIORITY JOURNAL; PROGRANULIN GENE; PROTEIN AGGREGATION; PROTEIN DEFECT; SYSTEMIC DISEASE; SYSTEMIC INFLAMMATION; TAUOPATHY;

AUTOIMMUNE DISEASES; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; HUMANS; MALE; TDP-43 PROTEINOPATHIES;

EID: 84878943418     PISSN: 17594758     EISSN: 17594766     Source Type: Journal    
DOI: 10.1038/nrneurol.2013.84     Document Type: Article

References (9)

1. Ratnavalli, E., Brayne, C., Dawson, K. & Hodges, J. R. The prevalence of frontotemporal dementia. Neurology 58, 1615-1621 (2002).
2. Boxer, A. L. et al. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development. Alzheimers Dement. 9, 176-188 (2013).
3. Miller, Z. A. et al. TDP-43 frontotemporal lobar degeneration and autoimmune disease. J. Neurol. Neurosurg. Psychiatry http://dx.doi.org/10.1136/ jnnp-2012-304644.
4. Gorno-Tempini, M. L. et al. Classification of primary progressive aphasia and its variants. Neurology 76, 1006-1014 (2011).
5. Rascovsky, K. et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain 134, 2456-2477 (2011).
6. Mackenzie, I. R. et al. A harmonized classification system for FTLD-TDP pathology. Acta Neuropathol. 122, 111-113 (2011).
7. Hodges, J. R. Hope abandoned: memantine therapy in frontotemporal dementia. Lancet Neurol. 12, 121-123 (2013).
8. Piguet, O. et al. Eating and hypothalamus changes in behavioral-variant frontotemporal dementia. Ann. Neurol. 69, 312-319 (2011).
9. Seelaar, H., Rohrer, J. D., Pijnenburg, Y. A., Fox, N. C. & van Swieten, J. C. Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review. J. Neurol. Neurosurg. Psychiatry 82, 478-486 (2011).