Meta-Analysis Indicates That the European GWAS-Identified Risk SNP rs1344706 within ZNF804A Is Not Associated with Schizophrenia in Han Chinese Population

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Li, Ming ^a,e   Zhang, Hui ^a   Luo, Xiong jian ^b   Gao, Lei ^c,e   Qi, Xue bin ^a   Gourraud, Pierre Antoine ^d   Su, Bing ^a  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c INSTITUTE OF PSYCHOLOGY   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; CHINESE; GENE; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; ZNF804A GENE;

ASIAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; POLYMORPHISM, SINGLE NUCLEOTIDE; REGRESSION ANALYSIS; SCHIZOPHRENIA;

EID: 84878942703     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065780     Document Type: Article

References (36)

1. Saha S, Chant D, Welham J, McGrath J, (2005) A systematic review of the prevalence of schizophrenia. PLoS Med 2: e141.
2. Sullivan PF, Kendler KS, Neale MC, (2003) Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry 60: 1187-1192.
3. Lichtenstein P, Bjork C, Hultman CM, Scolnick E, Sklar P, et al. (2006) Recurrence risks for schizophrenia in a Swedish national cohort. Psychol Med 36: 1417-1425.
4. Williams HJ, Owen MJ, O'Donovan MC, (2009) Schizophrenia genetics: new insights from new approaches. Br Med Bull 91: 61-74.
5. Owen MJ, Craddock N, O'Donovan MC, (2010) Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia. Arch Gen Psychiatry 67: 667-673.
6. Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, et al. (2011) Genome-wide association study identifies five new schizophrenia loci. Nat Genet 43: 969-976.
7. Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, et al. (2009) Common variants conferring risk of schizophrenia. Nature 460: 744-747.
8. Rietschel M, Mattheisen M, Degenhardt F, Muhleisen TW, Kirsch P, et al. (2011) Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe. Mol Psychiatry 17: 906-917.
9. O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, et al. (2008) Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet 40: 1053-1055.
10. Riley B, Thiselton D, Maher BS, Bigdeli T, Wormley B, et al. (2010) Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample. Mol Psychiatry 15: 29-37.
11. Zhang F, Chen Q, Ye T, Lipska BK, Straub RE, et al. (2011) Evidence of sex-modulated association of ZNF804A with schizophrenia. Biol Psychiatry 69: 914-917.
12. Steinberg S, Mors O, Borglum AD, Gustafsson O, Werge T, et al. (2011) Expanding the range of ZNF804A variants conferring risk of psychosis. Mol Psychiatry 16: 59-66.
13. Williams HJ, Norton N, Dwyer S, Moskvina V, Nikolov I, et al. (2011) Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Mol Psychiatry 16: 429-441.
14. Zhang R, Lu SM, Qiu C, Liu XG, Gao CG, et al. (2011) Population-based and family-based association studies of ZNF804A locus and schizophrenia. Mol Psychiatry 16: 360-361.
15. Xiao B, Li W, Zhang H, Lv L, Song X, et al. (2011) Association of ZNF804A polymorphisms with schizophrenia and antipsychotic drug efficacy in a Chinese Han population. Psychiatry Res 190: 379-381.
16. Chen M, Xu Z, Zhai J, Bao X, Zhang Q, et al. (2012) Evidence of IQ-modulated association between ZNF804A gene polymorphism and cognitive function in schizophrenia patients. Neuropsychopharmacology 37: 1572-1578.
17. Li M, Luo XJ, Xiao X, Shi L, Liu XY, et al. (2011) Allelic differences between Han Chinese and Europeans for functional variants in ZNF804A and their association with schizophrenia. Am J Psychiatry 168: 1318-1325.
18. Li M, Shi CJ, Shi YY, Luo XJ, Zheng XB, et al. (2012) ZNF804A and schizophrenia susceptibility in Asian populations. Am J Med Genet B Neuropsychiatr Genet 159B: 794-802.
19. Shi Y, Li Z, Xu Q, Wang T, Li T, et al. (2011) Common variants on 8p12 and 1q24.2 confer risk of schizophrenia. Nat Genet 43: 1224-1227.
20. Liou YJ, Wang HH, Lee MT, Wang SC, Chiang HL, et al. (2012) Genome-wide association study of treatment refractory schizophrenia in Han Chinese. PLoS One 7: e33598.
21. Xu S, Yin X, Li S, Jin W, Lou H, et al. (2009) Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet 85: 762-774.
22. Chanock SJ, Manolio T, Boehnke M, Boerwinkle E, Hunter DJ, et al. (2007) Replicating genotype-phenotype associations. Nature 447: 655-660.
23. Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, et al. (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460: 748-752.
24. Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, et al. (2009) Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 460: 753-757.
25. Li T, Li Z, Chen P, Zhao Q, Wang T, et al. (2010) Common variants in major histocompatibility complex region and TCF4 gene are significantly associated with schizophrenia in Han Chinese. Biol Psychiatry 68: 671-673.
26. Shifman S, Johannesson M, Bronstein M, Chen SX, Collier DA, et al. (2008) Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women. PLoS Genet 4: e28.
27. Li M, Luo XJ, Xiao X, Shi L, Liu XY, et al. (2013) Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population. World J Biol Psychiatry 14: 91-99.
28. Li M, Wang Y, Zheng XB, Ikeda M, Iwata N, et al. (2012) Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility. Schizophr Res 142: 200-205.
29. Pagel T, Baldessarini RJ, Franklin J, Baethge C (2013) Heterogeneity of schizoaffective disorder compared with schizophrenia and bipolar disorder. Acta Psychiatr Scand doi:10.1111/acps.12109.
30. Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, et al. (2008) Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet 40: 827-834.
31. Yue WH, Wang HF, Sun LD, Tang FL, Liu ZH, et al. (2011) Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet 43: 1228-1231.
32. Egger M, Davey Smith G, Schneider M, Minder C, (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315: 629-634.
33. Begg CB, Mazumdar M, (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50: 1088-1101.
34. Dupont WD, Plummer WD Jr, (1990) Power and sample size calculations. A review and computer program. Control Clin Trials 11: 116-128.
35. Zhong R, Tian Y, Liu L, Qiu Q, Wang Y, et al. (2012) HBV-related hepatocellular carcinoma susceptibility gene KIF1B is not associated with development of chronic hepatitis B. PLoS One. 7: e28839.
36. Gourraud PA, (2011) When is the absence of evidence, evidence of absence? Use of equivalence-based analyses in genetic epidemiology and a conclusion for the KIF1B rs10492972*C allelic association in multiple sclerosis. Genet Epidemiol 35: 568-571.