High prevalence of angiotropism in congenital melanocytic nevi: An analysis of 53 cases

American Journal of Dermatopathology

Volumn 35, Issue 2, 2013, Pages 180-183

  Kokta, Victor ^a   Hung, Tawny ^b   Al Dhaybi, Rola ^a   Lugassy, Claire ^c   Barnhill, Raymond L ^c  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UCLA MEDICAL CENTER   (United States)

Author keywords

Angiotropism; Congenital melanocytic nevi; Extravascular migration; Melanoma metastasis; Neural crest

Indexed keywords

ADULT; ANGIOTROPISM; ARTICLE; CHILD; DEVELOPMENTAL BIOLOGY; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MELANOCYTIC NEVUS; NEVUS CELL; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; SCHOOL CHILD; SKIN DEFECT;

ADOLESCENT; BLOOD VESSELS; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; LYMPHATIC VESSELS; MALE; NEVUS, PIGMENTED; SKIN NEOPLASMS; YOUNG ADULT;

EID: 84878938411     PISSN: 01931091     EISSN: 15330311     Source Type: Journal    
DOI: 10.1097/DAD.0b013e318260908c     Document Type: Article

References (11)

1. Ernfors P. Cellular origin and developmental mechanisms during the formation of skin melanocytes. Exp Cell Res. 2010;316:1397-1407.
2. Schwarz Q, Maden CH, Vieira JM, et al. Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification. Proc Natl Acad Sci U S A. 2009;106:6164-6169.
3. Nagy N, Mwizerwa O, Yaniv K, et al. Endothelial cells promote migration and proliferation of enteric neural crest cells via beta1 integrin signaling. Dev Biol. 2009;330:263-272.
4. Cramer SF. The melanocytic differentiation pathway in congenital melanocytic nevi: theoretical considerations. Pediatr Pathol. 1988;8: 253-265.
5. Barnhill RL. Congenital melanocytic nevi and associated neoplasms, congenital and childhood melanoma. In: Barnhill RL, Piepkorn M, Busam KJ, eds. Pathology of Melanocytic Nevi and Malignant Melanoma. 2nd ed. New York, NY: Springer; 2004:111-124.
6. Lyon VB. Congenital melanocytic nevi. Pediatr Clin North Am. 2010;57: 1155-1176.
7. Lugassy C, Barnhill RL. Angiotropism and extravascular migratory metastasis in melanoma: from concept to gene expression. Expert Rev Dermatol. 2011;6:303-316.
8. Barnhill RL, Chastain MA, Jerdan MS, et al. Angiotropic neonatal congenital melanocytic nevus: how extravascular migration of melanocytes may explain the development of congenital nevi. Am J Dermatopathol. 2010;32:495-499.
9. Lugassy C, Barnhill RL, Christensen L. Melanoma and extravascular migratory metastasis. J Cutan Pathol. 2000;27:281
10. Tokuda Y, Saida T, Murata H, et al. Histogenesis of congenital and acquired melanocytic nevi based on histological study of lesion size and thickness. J Dermatol. 2010;37:1011-1018.
11. Price HN, Schaffer JV. Congenital melanocytic nevi-when to worry and how to treat: facts and controversies. Clin Dermatol. 2010;28:293-302.