Auditory verbal hallucinations in schizophrenia correlate with P50 gating

Clinical Neurophysiology

Volumn 124, Issue 7, 2013, Pages 1329-1335

  Smith, Dylan M ^a   Grant, Bryan ^a   Fisher, Derek J ^a,b   Borracci, Giuseppe ^c   Labelle, Alain ^c   Knott, Verner J ^a,c  

^a UNIVERSITY OF OTTAWA   (Canada)

^b MOUNT SAINT VINCENT UNIVERSITY   (Canada)

^c ROYAL OTTAWA HOSPITAL   (Canada)

Author keywords

ERP; Gating; Hallucinations; P50; PSYRATS; Schizophrenia

Indexed keywords

ARTICLE; AUDITORY HALLUCINATION; AUDITORY NERVOUS SYSTEM; AUDITORY STIMULATION; AUDITORY VERBAL HALLUCINATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EVOKED RESPONSE; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; QUESTIONNAIRE; SCHIZOPHRENIA; SCORING SYSTEM; SENSORY GATING;

ACOUSTIC STIMULATION; ADULT; ANALYSIS OF VARIANCE; AUDITORY PATHWAYS; BRAIN MAPPING; CASE-CONTROL STUDIES; ELECTROENCEPHALOGRAPHY; EVOKED POTENTIALS, AUDITORY; FEMALE; HALLUCINATIONS; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; QUESTIONNAIRES; REACTION TIME; SCHIZOPHRENIA; SENSORY GATING;

EID: 84878935594     PISSN: 13882457     EISSN: 18728952     Source Type: Journal    
DOI: 10.1016/j.clinph.2013.02.004     Document Type: Article

References (55)

1. Adler L.E., Cawthra E.M., Donovan K.A., Harris J.G., Nagamoto H.T., Olincy A., et al. Improved P50 auditory gating with ondansetron in medicated schizophrenia patients. Am J Psychiatry 2005, 162:386-388.
2. Adler L.E., Hoffer L.J., Griffith J., Waldo M.C., Freedman R. Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics. Biol Psychiatry 1992, 32:607-616.
3. Adler L.E., Olincy A., Cawthra E.M., McRae K.A., Harris J.G., Nagamoto H.T., et al. varied effects of atypical neuroleptics on P50 auditory gating in schizophrenia patients. Am J Psychiartry 2004, 161:1822-1828.
4. Adler L.E., Pachtman E., Franks R.D., Pecevich M., Waldo M.C., Freedman R. Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia. Biol Psychiatry 1982, 17:639-654.
5. Allen A.J., Griss M.E., Folley B.S., Hawkins K.A., Pearlson G.D. Endophenotypes in schizophrenia: a selective review. Schizophr Res 2009, 109:24-37.
6. Andreasen N.C., Flaum M. Schizophrenia: the characteristic symptoms. Schizophr Bull 1991, 17:27-49.
7. Arnfred S.M. Exploration of auditory P50 gating in schizophrenia by way of difference waves. Behav Brain Funct 2006, 2:6.
8. Becker J., Gomes I., Ghisolfi E.S., Schuch A., Ramos F.L.P., Ehlers J.A., et al. Clozapine, but not typical antipsychotics, correct P50 suppression deficit in patients with schizophrenia. Clin Neurophysiol 2004, 115:396-401.
9. Bentall R.P., Slade P.D. Reality testing and auditory hallucinations: a signal detection analysis. Br J Clin Psychol 2011, 24:159-169.
10. Boutros N., Brockhaus-Dumke A., Gjini K., Vedeniapin A., Elfakhani M., Burroughs S., et al. Sensory-gating deficit of the N100 mid-latency auditory evoked potential in medicated schizophrenia patients. Schizophr Res 2009, 113:339-346.
11. Boutros N.N., Gjini K., Urbach H., Pflieger M.E. Mapping repetition suppression of the N100 evoked response to the human cerebral cortex. Biol Psychiatry 2011, 69:883-889.
12. Boutros N., Korzyukov O., Jansen B., Feingold A., Bell M. Sensory gating deficits during the mid-latency phase of information processing in medicated schizophrenia patients. Psychiatry Res 2004, 126:203-215.
13. Brenner C., Kieffaber P., Clementz B., Johannesen J., Shekhar A., O'Donnell B., et al. Event-related potential abnormalities in schizophrenia: a failure to "gate in" salient information?. Schizophr Res 2009, 114:332-338.
14. Brockhaus-Dumke A., Schultze-Lutter F., Mueller R., Tendolkar I., Bechdolf A., Pukrop R., et al. Sensory gating in schizophrenia: P50 and N100 gating in antipsychotic-free subjects at risk, first-episode, and chronic patients. Biol Psychiatry 2008, 64:376-384.
15. Chang W.-P., Arfken C.L., Sangal M.P., Boutros N.N. Probing the relative contribution of the first and second responses to sensory gating indices: a meta-analysis. Psychophysiology 2011, 48:980-992.
16. Clementz B.A., Geyer M.A., Braff D.L. P50 suppression among schizophrenia and normal comparison subjects: a methodological analysis. Biol Psychiatry 1997, 41:1035-1044.
17. Croft R.J., Lee A., Bertlolot J., Gruzelier J.H. Associations of P50 suppression and desensitization with perceptual and cognitive features of "unreality" in schizotypy. Biol Psychiatry 2001, 50:441-446.
18. Dalecki A., Croft R.J., Johnstone S.J. An evaluation of P50 paired-click methodologies. Psychophysiology 2011, 48:1692-1700.
19. Dierks T., Linden D.E.J., Jandl M., Formisano E., Goebel R., Lanfermann H., et al. Activation of Heschl's Gyrus during auditory hallucinations. Neuron 1999, 22:615-621.
20. Drake R., Haddock G., Tarrier N., Bentall R., Lewis S. The Psychotic Symptom Ratings Scales (PSYRATS): their usefulness and properties in first episode psychosis. Schizophr Res 2007, 89:119-122.
21. Fisher D.J., Labelle A., Knott V.J. The right profile: mismatch negativity in schizophrenia with and without auditory hallucinations as measured by a multi-feature paradigm. Clin Neurophysiol 2008, 119:909-921.
22. Fisher D.J., Labell A., Knott V.J. Auditory hallucinations and the mismatch negativity: processing speech and non-speech sounds in schizophrenia. Int J Psychophysiol 2008, 70:3-15.
23. Ford J.M., Dierks T., Fisher D.J., Hermann C.S., Hubl D., Kindler J., et al. Neurophysiological studies of auditory verbal hallucinations. Schizophr Bull 2012, 38:715-723.
24. Ford J.M., Mathalon D.H. Electrophysiological evidence of corollary discharge dysfunction in schizophrenia during talking and thinking. Psychiatry Res 2004, 38:37-46.
25. Freedman R., Adler L., Waldo M., Pachtman E., Franks R. Neurophysiological evidence for a defect in inhibitory pathways in schizophrenia: comparison of medicated and drug-free patients. Biol Psychiatry 1983, 18:537-551.
26. Freedman R., Waldo M., Bickford-Wimer P., Nagamoto H. Elementary neuronal dysfunctions in schizophrenia. Schizophr Res 1991, 4:233-243.
27. Fuerst D.R., Gallinat J., Boutros N.N. Range of sensory gating values and test-retest reliability in normal subjects. Psychophysiology 2007, 44:620-626.
28. Galdos M., Simons C., Fernandez-Rivas A., Wichers M., Peralta C., Lataster T., et al. Affectively salient meaning in random noise: a task sensitive to psychosis liability. Schizophr Bull 2011, 37:1179-1186.
29. Gjini K., Arfken C., Boutros N.N. Relationships between sensory "gating out" and sensory "gating in" of auditory evoked potentials in schizophrenia: a pilot study. Schizophr Res 2010, 121:139-145.
30. Gratton G., Coles M., Donchin E. A new method for off-line removal of ocular artifact. Electroencephalogr Clin Neurophysiol 1983, 55:468-484.
31. Haddock G., McCarron J., Tarrier N., Faragher E.B. Scales to measure dimensions of hallucinations and delusions: The Psychotic Symptom Ratings Scales (PSYRATS). Psychol Med 1999, 29:879-889.
32. Howes O.D., Kapur S. The dopamine hypothesis of schizophrenia: Version III. The final common pathway. Schizophr Bull 2009, 35:549-562.
33. Ishigaki T., Tanno Y. The signal detection ability of patients with auditory hallucination: analysis using the continuous performance test. Psychiatry Clin Neurosci 1999, 53:471-476.
34. Johannesen J., Kieffaber R., O'Donnell B., Shekhar A., Evans J., Hetrick W. Contributions of subtype and spectral frequency analyses to the study of P50 ERP amplitude and suppression in schizophrenia. Schizophr Res 2005, 78:269-284.
35. Kay S.R., Opler LA, Lindenmeyer J.P. The positive and negative syndrome scale (PANSS): rationale and standardization. Br J Psychiatry Suppl 1989, 155(Suppl. 7):59-65.
36. Koike K., Hashimoto K., Takai N., Shimizu E., Komatsu N., Watanabe H., et al. Tropisetron improves deficits in auditory P50 suppression in schizophrenia. Schizophr Res 2005, 76:67-72.
37. Korzyukov O., Pflieger M.E., Wagner M., Bowyer S.M., Rosburg T., Sundaresan K., et al. Generators of the intracranial P50 response in auditory sensory gating. Neuroimage 2007, 35:814-826.
38. Kühn S., Gallinat J. Quantitative meta-analysis on state and trait aspects of auditory verbal hallucinations in schizophrenia. Schizophr Bull 2012, 38:779-786.
39. Lee S.-H., Chung Y.-C., Yang J.-C., Kim Y.-K., Suh K.-Y. Abnormal speech perception in schizophrenia with auditory hallucinations. Acta Neuropsychol 2004, 16:154-159.
40. Light G.A., Braff D.L. Do self-reports of perceptual anomalies reflect gating deficits in schizophrenia patients?. Biol Psychiatry 2000, 47:463-467.
41. Margo A., Hemsley D.R., Slade P.D. The effects of varying auditory input on schizophrenic hallucinations. Br J Med Psychol 1981, 139:122-127.
42. Mathalon D.H., Ford J.M. Neurobiology of schizophrenia: search for the elusive correlation with symptoms. Front Hum Neurosci 2012, 6:136.
43. Näätänen R. Attention and brain function 1992, Erlbaum, Hillsdale, NJ.
44. Nagamoto H.T., Adler L.E., Hea R.A., Griffith J.M., McRae K.A., Freedman R. Gating of auditory P50 in schizophrenics: unique effects of clozapine. Biol Psychiatry 1996, 40:181-188.
45. Oades R.D., Zerbin D., Dittmann-Balcar A., Eggers C. Auditory event-related potential (ERP) and difference-wave topography in schizophrenic patients with/without active hallucinations and delusions: a comparison with young obsessive-compulsive disorder (OCD) and healthy subjects. Int J Psychophysiol 1996, 22:185-214.
46. Olincy A., Braff D.L., Adler L.E., Cadenhead K.S., Calkins M.E., Dobie D.J., et al. Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: results from the Consortium on Genetics of Schizophrenia. Schizophr Res 2010, 119:175-182.
47. Patterson J., Hetrick W., Boutros N., Jin Y., Sandman C., Stern H., et al. P50 sensory gating ratios in schizophrenics and controls: a review and data analysis. Psychiatry Res 2008, 158:226-247.
48. Plaze M., Bartrés-Faz D., Martinot J.L., Januel D., Bellivier F., De Beaurepaire R., et al. Left superior temporal gyrus activation during sentence perception negatively correlates with auditory hallucination severity in schizophrenia patients. Schizophr Res 2006, 87:109-115.
49. Rentzsch J., Jockers-Scherübl M.C., Boutros N.N., Gallinat J. Test-retest reliability of P50, N100 and P200 auditory sensory gating in healthy subjects. Int J Psychophysiol 2008, 67:81-90.
50. Rosburg T., Bourtros N.N., Ford J.M. Reduced auditory evoked potential component N100 in schizophrenia - a critical review. Psychiatry Res 2008, 161:259-274.
51. Shelley A.M., Silipo G., Javitt D.C. Diminished responsiveness of ERPs in schizophrenic subjects to changes in auditory stimulation parameters: implications for theories of cortical dysfunction. Schizophr Res 1999, 37:65-79.
52. Vercammen A., de Haan E.H.F., Aleman A. Hearing a voice in the noise: auditory hallucinations and speech perception. Psychol Med 2008, 38:1177-1184.
53. White P.M., Yee C.M. P50 sensitivity to physical and psychological state influences 2006. Psychophysiology 2006, 43:320-328.
54. Weisser R., Weisbrod M., Roehrig M., Rupp A., Schroeder J., Scherg M. Is frontal lobe involved in the generation of auditory evoked P50?. Neuroreport 2001, 12:3303-3307.
55. Woodruff P., Wright I., Bullmore E., Brammer M.J., Howard R.J., Williams S.C.R., et al. Auditory hallucinations and the temporal cortical response to speech in schizophrenia: a functional magnetic resonance imagining study. Am J Psychiatry 1997, 154:1676-1682.