Encapsulation of chimeric protein rSAG1/2 into poly(lactide-co-glycolide) microparticles induces long-term protective immunity against Toxoplasma gondii in mice

Experimental Parasitology

Volumn 134, Issue 4, 2013, Pages 430-437

  Chuang, Shu Chun ^a   Ko, Jing Chun ^b   Chen, Chaio Ping ^b   Du, Jia Tze ^b   Yang, Chung Da ^b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL PINGTUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Long term immunity; PLG rSAG1 2 microparticles; Poly(lactide co glycolide) (PLG); RSAG1 2; Toxoplasma gondii (T. gondii)

Indexed keywords

GAMMA INTERFERON; POLYGLACTIN; RECOMBINANT PROTEIN; RECOMBINANT SAG1 PROTEIN; RECOMBINANT SAG2 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG ANTIGENICITY; DRUG EFFICACY; DRUG RELEASE; DRUG STABILITY; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; LONG TERM IMMUNITY; LYMPHOCYTE PROLIFERATION; MICROENCAPSULATION; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTECTION; TOXOPLASMA GONDII; TOXOPLASMOSIS; WESTERN BLOTTING;

LONG-TERM IMMUNITY; PLG-RSAG1/2 MICROPARTICLES; POLY(LACTIDE-CO-GLYCOLIDE) (PLG); RSAG1/2; TOXOPLASMA GONDII (T. GONDII);

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; BIOCOMPATIBLE MATERIALS; CAPSULES; DELAYED-ACTION PREPARATIONS; IMMUNE SERA; IMMUNITY, CELLULAR; IMMUNIZATION; INTERFERON-GAMMA; LACTIC ACID; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POLYGLYCOLIC ACID; PROTOZOAN PROTEINS; RABBITS; RECOMBINANT FUSION PROTEINS; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL;

ANIMALIA; MUS; TOXOPLASMA; TOXOPLASMA GONDII;

EID: 84878923558     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2013.04.002     Document Type: Article

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