17β-estradiol impedes bax-involved mitochondrial apoptosis of retinal nerve cells induced by oxidative damage via the phosphatidylinositol 3-kinase/akt signal pathway

Journal of Molecular Neuroscience

Volumn 50, Issue 3, 2013, Pages 482-493

  Li, Hongbo ^a   Wang, Baoying ^a   Zhu, Chunhui ^a   Feng, Yan ^a   Wang, Shaolan ^a   Shahzad, Muhammad ^b   Hu, Chenghu ^a   Mo, Mingshu ^a   Du, Fangying ^a   Yu, Xiaorui ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b UNIVERSITY OF HEALTH SCIENCES   (Pakistan)

Author keywords

17 Estradiol; Apoptosis; Bax; Caspase; Oxidative stress; PI3K Akt

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; APOPTOSOME; CASPASE 3; CASPASE 9; ESTRADIOL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN KINASE B;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; INTRACELLULAR SIGNALING; NEUROPROTECTION; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; RETINA NERVE CELL; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; APOPTOSIS; APOPTOSOMES; BCL-2-ASSOCIATED X PROTEIN; CELLS, CULTURED; ESTRADIOL; HYDROGEN PEROXIDE; MITOCHONDRIA; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION;

EID: 84878918126     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-9968-9     Document Type: Article

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