Impaired Glucose Tolerance in a Mouse Model of Sidt2 Deficiency

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Gao, Jialin ^a,d   Gu, Xuefan ^a   Mahuran, Don J ^b   Wang, Zhugang ^c   Zhang, Huiwen ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c Shanghai Research Center for Model Organisms   (China)

^d WANNAN MEDICAL COLLEGE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; POTASSIUM CHLORIDE; PROTEIN SIDT2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL MEMBRANE DEPOLARIZATION; CELL VACUOLE; CONCENTRATION (PARAMETERS); EMBRYO; FEMALE; GENE TARGETING; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; IMMUNOFLUORESCENCE; IMPAIRED GLUCOSE TOLERANCE; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; INTRAPERITONEAL GLUCOSE TOLERANCE TEST; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET CELL; SECRETORY GRANULE; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOSE INTOLERANCE; INSULIN; ISLETS OF LANGERHANS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; SECRETORY VESICLES;

MUS;

EID: 84878913424     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066139     Document Type: Article

References (38)

1. Cullen PJ, Carlton JG, (2012) Phosphoinositides in the Mammalian Endo-lysosomal Network. Subcell Biochem 59: 65-110.
2. Boadu E, Nelson RC, Francis GA, (2012) ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein. Biochim Biophys Acta 1821: 396-404.
3. Rosa-Ferreira C, Munro S, (2011) Arl8 and SKIP act together to link lysosomes to kinesin-1. Dev Cell 21: 1171-1178.
4. O′Prey J, Skommer J, Wilkinson S, Ryan KM, (2009) Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy. Cell Cycle 8: 2260-2265.
5. Ramonet D, Podhajska A, Stafa K, Sonnay S, Trancikova A, et al. (2012) PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity. Hum Mol Genet 21: 1725-1743.
6. Schwake M, Schroder B, Saftig P (2013) Lysosomal Membrane Proteins and their central role in physiology. Traffic.
7. Poon PY, Dornan TL, Ellis RB, Turner RC, (1979) Increased plasma activities of N-acetyl-beta-D-glucosaminidase isoenzymes in human diabetes mellitus. Clin Endocrinol (Oxf) 11: 625-630.
8. Waters PJ, Flynn MD, Corrall RJ, Pennock CA, (1992) Increases in plasma lysosomal enzymes in type 1 (insulin-dependent) diabetes mellitus: relationship to diabetic complications and glycaemic control. Diabetologia 35: 991-995.
9. Lundquist I, Lovdahl R, (1983) Effect of fasting on islet lysosomal enzyme activities and the in vivo insulin response to different secretagogues. Horm Metab Res 15: 11-14.
10. Lundquist I, Panagiotidis G, Salehi A, (1996) Islet acid glucan-1,4-alpha-glucosidase: a putative key enzyme in nutrient-stimulated insulin secretion. Endocrinology 137: 1219-1225.
11. Salehi A, Henningsson R, Mosen H, Ostenson CG, Efendic S, et al. (1999) Dysfunction of the islet lysosomal system conveys impairment of glucose-induced insulin release in the diabetic GK rat. Endocrinology 140: 3045-3053.
12. Meijer AJ, Codogno P, (2008) Autophagy: a sweet process in diabetes. Cell Metab 8: 275-276.
13. Brunner Y, Coute Y, Iezzi M, Foti M, Fukuda M, et al. (2007) Proteomics analysis of insulin secretory granules. Mol Cell Proteomics 6: 1007-1017.
14. Rutter GA, Hill EV, (2006) Insulin vesicle release: walk, kiss, pause then run. Physiology (Bethesda) 21: 189-196.
15. Schroder B, Wrocklage C, Pan C, Jager R, Kosters B, et al. (2007) Integral and associated lysosomal membrane proteins. Traffic 8: 1676-1686.
16. Saftig P, Klumperman J, (2009) Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat Rev Mol Cell Biol 10: 623-635.
17. Zhang H, Fan X, Bagshaw RD, Zhang L, Mahuran DJ, et al. (2007) Lysosomal membranes from beige mice contain higher than normal levels of endoplasmic reticulum proteins. J Proteome Res 6: 240-249.
18. Jialin G, Xuefan G, Huiwen Z, (2010) SID1 transmembrane family, member 2 (Sidt2): a novel lysosomal membrane protein. Biochem Biophys Res Commun 402: 588-594.
19. Elhassan MO, Christie J, Duxbury MS, (2012) Homo sapiens systemic RNA interference-defective-1 transmembrane family member 1 (SIDT1) protein mediates contact-dependent small RNA transfer and microRNA-21-driven chemoresistance. J Biol Chem 287: 5267-5277.
20. Ren R, Xu X, Lin T, Weng S, Liang H, et al. (2011) Cloning, characterization, and biological function analysis of the SidT2 gene from Siniperca chuatsi. Dev Comp Immunol 35: 692-701.
21. Andrejewski N, Punnonen EL, Guhde G, Tanaka Y, Lullmann-Rauch R, et al. (1999) Normal lysosomal morphology and function in LAMP-1-deficient mice. J Biol Chem 274: 12692-12701.
22. Nishino I, Fu J, Tanji K, Yamada T, Shimojo S, et al. (2000) Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature 406: 906-910.
23. Kos CH, (2004) Cre/loxP system for generating tissue-specific knockout mouse models. Nutr Rev 62: 243-246.
24. Zheng B, Sage M, Sheppeard EA, Jurecic V, Bradley A, (2000) Engineering mouse chromosomes with Cre-loxP: range, efficiency, and somatic applications. Mol Cell Biol 20: 648-655.
25. Lacy PE, Kostianovsky M, (1967) Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16: 35-39.
26. Hanna ST, Pigeau GM, Galvanovskis J, Clark A, Rorsman P, et al. (2009) Kiss-and-run exocytosis and fusion pores of secretory vesicles in human beta-cells. Pflugers Arch 457: 1343-1350.
27. Bonner-Weir S, Orci L, (1982) New perspectives on the microvasculature of the islets of Langerhans in the rat. Diabetes 31: 883-889.
28. Obermuller S, Calegari F, King A, Lindqvist A, Lundquist I, et al. Defective secretion of islet hormones in chromogranin-B deficient mice. PLoS One 5: e8936.
29. Ceridono M, Ory S, Momboisse F, Chasserot-Golaz S, Houy S, et al. (2011) Selective recapture of secretory granule components after full collapse exocytosis in neuroendocrine chromaffin cells. Traffic 12: 72-88.
30. Obermuller S, Lindqvist A, Karanauskaite J, Galvanovskis J, Rorsman P, et al. (2005) Selective nucleotide-release from dense-core granules in insulin-secreting cells. J Cell Sci 118: 4271-4282.
31. MacDonald PE, Obermuller S, Vikman J, Galvanovskis J, Rorsman P, et al. (2005) Regulated exocytosis and kiss-and-run of synaptic-like microvesicles in INS-1 and primary rat beta-cells. Diabetes 54: 736-743.
32. Gustavsson N, Lao Y, Maximov A, Chuang JC, Kostromina E, et al. (2008) Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice. Proc Natl Acad Sci U S A 105: 3992-3997.
33. Chakrabarti S, Kobayashi KS, Flavell RA, Marks CB, Miyake K, et al. (2003) Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice. J Cell Biol 162: 543-549.
34. Dong XP, Cheng X, Mills E, Delling M, Wang F, et al. (2008) The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel. Nature 455: 992-996.
35. Lloyd-Evans E, Platt FM, (2011) Lysosomal Ca(2+) homeostasis: role in pathogenesis of lysosomal storage diseases. Cell Calcium 50: 200-205.
36. LaPlante JM, Sun M, Falardeau J, Dai D, Brown EM, et al. (2006) Lysosomal exocytosis is impaired in mucolipidosis type IV. Mol Genet Metab 89: 339-348.
37. Rutter GA, Tsuboi T, Ravier MA, (2006) Ca2+ microdomains and the control of insulin secretion. Cell Calcium 40: 539-551.
38. Dixit SS, Wang T, Manzano EJ, Yoo S, Lee J, et al. (2013) Effects of CaMKII-Mediated Phosphorylation of Ryanodine Receptor Type 2 on Islet Calcium Handling, Insulin Secretion, and Glucose Tolerance. PLoS One 8: e58655.