Hepatic steatosis estimated microscopically versus digital image analysis

Liver International

Volumn 33, Issue 6, 2013, Pages 926-935

  Hall, Andrew R ^a   Dhillon, Amar P ^b   Green, Anna C ^a   Ferrell, Linda ^c   Crawford, James M ^d   Alves, Venancio ^e   Balabaud, Charles ^f   Bhathal, Prithi ^g   Bioulac Sage, Paulette ^f,h   Guido, Maria ⁱ   Hytiroglou, Prodromos ^j   Nakanuma, Yasuni ^k   Paradis, Valerie ^l   Quaglia, Alberto ^m   Snover, Dale ⁿ   Theise, Neil ^o   Thung, Swan ^p   Tsui, Wilson ^q   Van Leeuwen, Dirk J ^r,s  

^a ROYAL FREE LONDON NHS FOUNDATION TRUST   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

^f UNIVERSITÉ DE BORDEAUX   (France)

^g UNIVERSITY OF MELBOURNE   (Australia)

^h HÔPITAL PELLEGRIN   (France)

ⁱ UNIVERSITY OF PADOVA   (Italy)

^j ARISTOTLE UNIVERSITY MEDICAL SCHOOL   (Greece)

^k KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^l BEAUJON HOSPITAL   (France)

^m KING S COLLEGE HOSPITAL   (United Kingdom)

ⁿ FAIRVIEW SOUTHDALE HOSPITAL   (United States)

^o BETH ISRAEL MEDICAL CENTER   (United States)

^p MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^q Caritas Medical Centre Hong Kong   (Hong Kong)

^r ONZE LIEVE VROUWE GASTHUIS   (Netherlands)

^s DARTMOUTH MEDICAL SCHOOL   (United States)

more..

Author keywords

Alcoholic liver disease; Digital image analysis; Estimated fat proportionate area; Fat proportionate area; Fat quantification; Measured fat proportionate area; Non alcoholic fatty liver disease; Steatosis

Indexed keywords

ACCURACY; ARTICLE; CLINICAL ARTICLE; CLINICAL EVALUATION; CONSENSUS; CORRELATION COEFFICIENT; DIGITAL IMAGING; DISEASE SEVERITY; FAT CONTENT; FAT PROPORTIONATE AREA; FATTY LIVER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; LIVER BIOPSY; LIVER PARENCHYMA; STANDARDIZATION;

ADIPOSITY; ASIA; BIOPSY; BRAZIL; CONSENSUS; EUROPE; FATTY LIVER; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; LIVER; MICROSCOPY; OBSERVER VARIATION; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SEVERITY OF ILLNESS INDEX; UNITED STATES;

EID: 84878897156     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12162     Document Type: Article

References (34)

1. Tiniakos DG. Nonalcoholic fatty liver disease/nonalcoholic steatohepatitis: histological diagnostic criteria and scoring systems. Eur J Gastroenterol Hepatol 2010; 22: 643-50.
2. Bondini S, Kleiner DE, Goodman ZD, Gramlich T, Younossi ZM. Pathologic assessment of non-alcoholic fatty liver disease. Clin Liver Dis 2007;11:17-23.
3. Yeh MM, Brunt EM. Pathology of nonalcoholic fatty liver disease. Am J Clin Pathol 2007; 128: 837-47.
4. Clavien PA, Petrowsky H, DeOliveira ML, Graf R. Strategies for safer liver surgery and partial liver transplantation. N Engl J Med 2007; 356: 1545-59.
5. de Meijer V, Kalish BT, Puder M, Ijzermans JN. Systematic review and meta-analysis of steatosis as a risk factor in major hepatic resection. Br J Surg 2010; 97: 1331-9.
6. McCormack L, Petrowsky H, Jochum W, Furrer K, Clavien PA. Hepatic steatosis is a risk factor for postoperative complications after major hepatectomy: a matched case-control study. Ann Surg 2007; 245: 923-30.
7. Verran D, Kusyk T, Painter D, et al. Clinical experience gained from the use of 120 steatotic donor livers for orthotopic liver transplantation. Liver Transpl 2003; 9: 500-5.
8. Lee SS, Park SH, Kim HJ, et al. Non-invasive assessment of hepatic steatosis: prospective comparison of the accuracy of imaging examinations. J Hepatol 2010; 52 : 579-85.
9. Longo R, Ricci C, Masutti F, et al. Fatty infiltration of the liver. Quantification by 1H localized magnetic resonance spectroscopy and comparison with computed tomography. Invest Radiol 1993; 28: 297-302.
10. Longo R, Pollesello P, Ricci C, et al. Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis. J Magn Reson Imaging 1995; 5: 281-5.
11. Springer F, Machann J, Claussen CD, Schick F, Schwenzer NF. Liver fat content determined by magnetic resonance imaging and spectroscopy. World J Gastroenterol 2010; 16: 1560-6.
12. Farrell GC, Teoh NC, McCuskey RS. Hepatic microcirculation in fatty liver disease. Anat Rec 2008; 291: 684-92.
13. Fiorini RN, Kirtz J, Periyasamy B, et al. Development of an unbiased method for the estimation of liver steatosis. Clin Transplant 2004; 18: 700-6.
14. Franzen LE, Ekstedt M, Kechagias S, Bodin L. Semiquantitative evaluation overestimates the degree of steatosis in liver biopsies: a comparison to stereological point counting. Mod Pathol 2005; 18: 912-16.
15. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 1999; 94: 2467-74.
16. El-Badry AM, Breitenstein S, Jochum W, et al. Assessment of hepatic steatosis by expert pathologists: the end of a gold standard. Ann Surg 2009; 250: 691-7.
17. Kumar D, Farrell GC, Fung C, George J. Hepatitis C virus genotype 3 is cytopathic to hepatocytes: reversal of hepatic steatosis after sustained therapeutic response. Hepatology 2002; 36: 1266-72.
18. Kleiner DE, Brunt EM, Van NM, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41: 1313-21.
19. Auger J, Schoevaert D, Martin ED. Comparative study of automated morphometric and semiquantitative estimations of alcoholic liver steatosis. Anal Quant Cytol Histol 1986; 8: 56-62.
20. Levene AP, Kudo H, Armstrong MJ, et al. Quantifying hepatic steatosis - more than meets the eye. Histopathology 2012; 60: 971-81.
21. Marsman H, Matsushita T, Dierkhising R, et al. Assessment of donor liver steatosis: pathologist or automated software? Hum Pathol 2004; 35: 430-5.
22. Boyles TH, Johnson S, Garrahan N, Freedman AR, Williams GT. A validated method for quantifying macrovesicular hepatic steatosis in chronic hepatitis C. Anal Quant Cytol Histol 2007; 29: 244-50.
23. Bedossa P, Poynard T, Naveau S, et al. Observer variation in assessment of liver biopsies of alcoholic patients. Alcohol Clin Exp Res 1988; 12: 173-8.
24. Younossi ZM, Gramlich T, Liu YC, et al. Nonalcoholic fatty liver disease: assessment of variability in pathologic interpretations. Mod Pathol 1998; 11: 560-5.
25. Friedrich-Rust M, Romen D, Vermehren J, et al. Acoustic radiation force impulse-imaging and transient elastography for non-invasive assessment of liver fibrosis and steatosis in NAFLD. Eur J Radiol 2012; 81: e325-31.
26. van Warven JR, Marsman HA, Nederveen AJ, et al. Assessment of hepatic steatosis in patients undergoing liver resection: comparison of US, CT, T1-weighted dual-echo MR imaging, and point-resolved 1H MR spectroscopy. Radiology 2010; 256: 159-68.
27. Tsybrovskyy O, Rossmann-Tsybrovskyy M, Regitnig P. BackgroundCorrector - a software program for fast and user-friendly improvement of digital photomicrographs. Histopathology 2011; 59: 341-2.
28. Fleiss JL. Statistical Methods for Rates and Proportions. Wiley Series in Probability and Mathematical Statistics. 2nd edn. New York: Wiley, 1981; 212-36.
29. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977; 33: 159-74.
30. Shrout PE, Fleiss JL. Intraclass correlations: uses in assessing rater reliability. Psychol Bull 1979; 86: 420-8.
31. Brunt EM, Neuschwander-Tetri BA, Burt AD. Fatty liver disease: alcoholic and non-alcoholic. In: Burt A, Portmann B, Ferrell L, eds. MacSween's Pathology of the Liver, 6th edn. Edinburgh: Churchill Livingstone (Elsevier), 2012; 326.
32. D'Alessandro AM, Kalayoglu M, Sollinger HW, et al. The predictive value of donor liver biopsies for the development of primary nonfunction after orthotopic liver transplantation. Transplantation 1991; 51: 157-63.
33. McCormack L, Petrowsky H, Jochum W, et al. Use of severely steatotic grafts in liver transplantation: a matched case-control study. Ann Surg 2007; 246: 940-8.
34. Ricci C, Longo R, Gioulis E, et al. Noninvasive in vivo quantitative assessment of fat content in human liver. J Hepatol 1997; 27: 108-13.