Fibulin-1 is down-regulated through promoter hypermethylation and suppresses renal cell carcinoma progression

Journal of Urology

Volumn 190, Issue 1, 2013, Pages 291-301

  Xiao, Wei ^a   Wang, Ji ^d   Li, Heng ^a   Guan, Wei ^a   Xia, Ding ^a   Yu, Gan ^a   Xiao, Haibing ^a   Lang, Bin ^c   Ma, Xin ^b   Liu, Jihong ^a   Zhang, Xu ^b   Ye, Zhangqun ^a   Xu, Hua ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c MACAO POLYTECHNIC INSTITUTE   (Macao)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

angiogenesis inhibitors; carcinoma, renal cell; fibulin genes, tumor suppressor; kidney

Indexed keywords

FIBULIN 1 PROTEIN; LENTIVIRUS VECTOR; MESSENGER RNA; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL ADHESION; CELL GROWTH; CELL MOTILITY; CELL VIABILITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA METHYLATION; DOWN REGULATION; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; METHYLATION SPECIFIC POLYMERASE CHAIN REACTION; MOUSE; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER HYPERMETHYLATION; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANGIOGENESIS INHIBITORS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CALCIUM-BINDING PROTEINS; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CELL SURVIVAL; DISEASE PROGRESSION; DNA METHYLATION; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY NEOPLASMS; MICE; MICE, NUDE; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY;

EID: 84878889386     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2013.01.098     Document Type: Article

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