메뉴 건너뛰기




Volumn 14, Issue 2, 2013, Pages 61-67

Immune activation while on potent antiretroviral therapy can predict subsequent CD4+ T-cell increases through 15 years of treatment

Author keywords

antiretroviral therapy; CD4+ T cell counts; HIV; immune activation

Indexed keywords

ABACAVIR; CD4 ANTIGEN; CD8 ANTIGEN; INDINAVIR; LAMIVUDINE; STAVUDINE; VIRUS RNA; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

EID: 84878888619     PISSN: 15284336     EISSN: 19455771     Source Type: Journal    
DOI: 10.1310/hct1402-61     Document Type: Article
Times cited : (21)

References (21)
  • 1
    • 0038701685 scopus 로고    scopus 로고
    • T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy
    • Hunt PW, Martin JN, Sinclair E, et al. T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J Infect Dis. 2003;187(10):1534-1543.
    • (2003) J Infect Dis. , vol.187 , Issue.10 , pp. 1534-1543
    • Hunt, P.W.1    Martin, J.N.2    Sinclair, E.3
  • 2
    • 33745891216 scopus 로고    scopus 로고
    • Effect of baseline-and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: Results from ACTG 384
    • Gandi RT, Spritzler J, Chan E, et al. Effect of baseline-and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: results from ACTG 384. J Acquir Immune Defic Syndr. 2006;42:426-434.
    • (2006) J Acquir Immune Defic Syndr. , vol.42 , pp. 426-434
    • Gandi, R.T.1    Spritzler, J.2    Chan, E.3
  • 3
    • 33745214932 scopus 로고    scopus 로고
    • Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: Association of immune activation, T cell maturation markers, and cellular HIV-1 DNA
    • Goicoechea M, Smith DM, Liu L, May S, Tenorio AR, Ignacio CC. Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: association of immune activation, T cell maturation markers, and cellular HIV-1 DNA. J Infect Dis. 2006;194:29-37.
    • (2006) J Infect Dis. , vol.194 , pp. 29-37
    • Goicoechea, M.1    Smith, D.M.2    Liu, L.3    May, S.4    Tenorio, A.R.5    Ignacio, C.C.6
  • 4
    • 80055049890 scopus 로고    scopus 로고
    • Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy
    • Hunt PW, Cao HL, Muzoora C, et al. Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy. AIDS. 2011;25:2123-2131.
    • (2011) AIDS , vol.25 , pp. 2123-2131
    • Hunt, P.W.1    Cao, H.L.2    Muzoora, C.3
  • 5
    • 78751559513 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of abacavir intensification in HIV-1-infected adults with virologic suppression on a protease inhibitor-containing regimen
    • Hammer SM, Ribaudo H, Bassett R, et al. A randomized, placebo-controlled trial of abacavir intensification in HIV-1-infected adults with virologic suppression on a protease inhibitor-containing regimen. HIV Clin Trials. 2010;11(6):312-324.
    • (2010) HIV Clin Trials. , vol.11 , Issue.6 , pp. 312-324
    • Hammer, S.M.1    Ribaudo, H.2    Bassett, R.3
  • 6
    • 51949108746 scopus 로고    scopus 로고
    • AIDS Clinical Trials Group Longitudinal Linked Randomized Trials (ALLRT): Rationale, design, and baseline characteristics
    • Smurzynski M, Collier AC, Koletar SL, et al. AIDS Clinical Trials Group Longitudinal Linked Randomized Trials (ALLRT): rationale, design, and baseline characteristics. HIV Clin Trials. 2008;9(4):269-282.
    • (2008) HIV Clin Trials. , vol.9 , Issue.4 , pp. 269-282
    • Smurzynski, M.1    Collier, A.C.2    Koletar, S.L.3
  • 7
    • 0442268112 scopus 로고    scopus 로고
    • A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team
    • Hammer SM, Squires KE, Hughes MD, et al. A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. N Engl J Med. 1997;337(11):725-733
    • (1997) N Engl J Med. , vol.337 , Issue.11 , pp. 725-733
    • Hammer, S.M.1    Squires, K.E.2    Hughes, M.D.3
  • 9
    • 77950947891 scopus 로고    scopus 로고
    • CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART
    • Massanella M, Negredo E, Pérez-Alvarez N, et al. CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART. AIDS. 2010;24(7):959-968.
    • (2010) AIDS , vol.24 , Issue.7 , pp. 959-968
    • Massanella, M.1    Negredo, E.2    Pérez-Alvarez, N.3
  • 10
    • 0037900857 scopus 로고    scopus 로고
    • Immunological and virological failure after antiretroviral therapy is associated with enhanced peripheral and thymic pathogenicity
    • Solomon A, Cameron PU, Bailey M, et al. Immunological and virological failure after antiretroviral therapy is associated with enhanced peripheral and thymic pathogenicity. J Infect Dis. 2003;187(12):1915-1923.
    • (2003) J Infect Dis. , vol.187 , Issue.12 , pp. 1915-1923
    • Solomon, A.1    Cameron, P.U.2    Bailey, M.3
  • 11
    • 67650664983 scopus 로고    scopus 로고
    • Sub-optimal CD4 recovery on long-term suppressive highly active antiretroviral therapy is associated with favourable outcome
    • Onen NF, Overton ET, Presti R, Blair C, Powderly WG, Mondy K. Sub-optimal CD4 recovery on long-term suppressive highly active antiretroviral therapy is associated with favourable outcome. HIV Med. 2009;10(7):439-446.
    • (2009) HIV Med. , vol.10 , Issue.7 , pp. 439-446
    • Onen, N.F.1    Overton, E.T.2    Presti, R.3    Blair, C.4    Powderly, W.G.5    Mondy, K.6
  • 12
    • 62449222132 scopus 로고    scopus 로고
    • Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment
    • Kelley C F, Kitchen CM, Hunt PW, et al. Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment. Clin Infect Dis. 2009;48(6):787-794.
    • (2009) Clin Infect Dis. , vol.48 , Issue.6 , pp. 787-794
    • Kelley, C.F.1    Kitchen, C.M.2    Hunt, P.W.3
  • 13
    • 42449086328 scopus 로고    scopus 로고
    • CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection
    • Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA)
    • Baker JV, Peng G, Rapkin J, et al; Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA). CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection. AIDS. 2008;22(7): 841-848.
    • (2008) AIDS , vol.22 , Issue.7 , pp. 841-848
    • Baker, J.V.1    Peng, G.2    Rapkin, J.3
  • 14
    • 78549245806 scopus 로고    scopus 로고
    • Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy
    • Yukl SA, Shergill AK, McQuaid K, et al. Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy. AIDS. 2010; 24(16):2451-2460.
    • (2010) AIDS , vol.24 , Issue.16 , pp. 2451-2460
    • Yukl, S.A.1    Shergill, A.K.2    McQuaid, K.3
  • 15
    • 65649102237 scopus 로고    scopus 로고
    • Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection
    • Jiang W, Lederman MM, Hunt PW, et al. Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection. J Infect Dis. 2009;199(8):1177-1185.
    • (2009) J Infect Dis. , vol.199 , Issue.8 , pp. 1177-1185
    • Jiang, W.1    Lederman, M.M.2    Hunt, P.W.3
  • 16
    • 79955028940 scopus 로고    scopus 로고
    • Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy
    • Hunt PW, Martin JN, Sinclair E, et al. Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy. J Infect Dis. 2011;203(10):1474-1483.
    • (2011) J Infect Dis. , vol.203 , Issue.10 , pp. 1474-1483
    • Hunt, P.W.1    Martin, J.N.2    Sinclair, E.3
  • 17
    • 79955962732 scopus 로고    scopus 로고
    • HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesis
    • Sauce D, Larsen M, Fastenackels S, et al. HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesis. Blood. 2011;117(19):5142-5151.
    • (2011) Blood. , vol.117 , Issue.19 , pp. 5142-5151
    • Sauce, D.1    Larsen, M.2    Fastenackels, S.3
  • 18
    • 79952216365 scopus 로고    scopus 로고
    • Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections
    • Zeng M, Smith AJ, Wietgrefe SW, et al. Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections. J Clin Invest. 2011;121(3): 998-1008.
    • (2011) J Clin Invest. , vol.121 , Issue.3 , pp. 998-1008
    • Zeng, M.1    Smith, A.J.2    Wietgrefe, S.W.3
  • 19
    • 27744560468 scopus 로고    scopus 로고
    • CD4+ T-cell death induced by infectious and noninfectious HIV-1: Role of type 1 interferon-dependent TRAIL/DR5-mediated apoptosis
    • Herbeuval J P, Grivel JC, Boasso A, et al. CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis. Blood. 2005;106(10):3524-3531.
    • (2005) Blood. , vol.106 , Issue.10 , pp. 3524-3531
    • Herbeuval, J.P.1    Grivel, J.C.2    Boasso, A.3
  • 20
    • 0033394585 scopus 로고    scopus 로고
    • Immune reconstitution after 2 years of successful potent antiretroviral therapy in previously untreated human immunodeficiency virus type 1-infected adults
    • Notermans DW, Pakker NG, Hamann D. Immune reconstitution after 2 years of successful potent antiretroviral therapy in previously untreated human immunodeficiency virus type 1-infected adults. J Infect Dis. 1999;180:1050-1056.
    • (1999) J Infect Dis. , vol.180 , pp. 1050-1056
    • Notermans, D.W.1    Pakker, N.G.2    Hamann, D.3
  • 21
    • 67650590873 scopus 로고    scopus 로고
    • IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection
    • Sereti I, Dunham RM, Spritzler J, et al. IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection. Blood. 2009;113:6304-6314.
    • (2009) Blood. , vol.113 , pp. 6304-6314
    • Sereti, I.1    Dunham, R.M.2    Spritzler, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.