Decreased platelet miR-223 expression is associated with high on-clopidogrel platelet reactivity

Thrombosis Research

Volumn 131, Issue 6, 2013, Pages 508-513

  Shi, Rui ^a   Ge, Lan ^a   Zhou, Xin ^a   Ji, Wen Jie ^b   Lu, Rui Yi ^a   Zhang, Ying Ying ^a   Zeng, Shan ^a   Liu, Xing ^a   Zhao, Ji Hong ^a   Zhang, Wen Cheng ^b   Jiang, Tie Min ^a   Li, Yu Ming ^a  

^a MEDICAL COLLEGE OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

^b Logistics University of Chinese People's Armed Police Forces   (China)

Author keywords

Clopidogrel; High on treatment platelet reactivity; MiroRNAs; Platelet function test; Vasodilator stimulated phosphoprotein

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CLOPIDOGREL; MICRORNA; MICRORNA 223; MICRORNA 96; PROTON PUMP INHIBITOR; UNCLASSIFIED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN;

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; FLOW CYTOMETRY; GENOTYPE; HUMAN; ISCHEMIC HEART DISEASE; LOADING DRUG DOSE; MALE; OBESITY; PLATELET REACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PURIFICATION; REAL TIME POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA ISOLATION; SMOKING; THROMBOCYTE; THROMBOCYTE AGGREGATION; TREATMENT RESPONSE;

AGED; BLOOD PLATELETS; CORONARY DISEASE; DOWN-REGULATION; FEMALE; HUMANS; MALE; MICRORNAS; MIDDLE AGED; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET FUNCTION TESTS; TICLOPIDINE;

EID: 84878863067     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2013.02.015     Document Type: Article

References (35)

1. H. Jneid, J.L. Anderson, R.S. Wright, C.D. Adams, C.R. Bridges, and D.E. Casey Jr. 2012 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines J Am Coll Cardiol 60 2012 645 681
2. D. Aradi, A. Komocsi, A. Vorobcsuk, O. Rideg, M. Tokes-Fuzesi, and T. Magyarlaki Prognostic significance of high on-clopidogrel platelet reactivity after percutaneous coronary intervention: systematic review and meta-analysis Am Heart J 160 2010 543 551
3. N.J. Breet, J.W. van Werkum, H.J. Bouman, J.C. Kelder, A.M. Harmsze, and C.M. Hackeng High on-treatment platelet reactivity to both aspirin and clopidogrel is associated with the highest risk of adverse events following percutaneous coronary intervention Heart 97 2011 983 990
4. J.L. Mega, S.L. Close, S.D. Wiviott, L. Shen, R.D. Hockett, and J.T. Brandt Cytochrome p-450 polymorphisms and response to clopidogrel N Engl J Med 360 2009 354 362
5. A.R. Shuldiner, J.R. O'Connell, K.P. Bliden, A. Gandhi, K. Ryan, and R.B. Horenstein Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy JAMA 302 2009 849 857
6. J.M. Siller-Matula, I. Lang, G. Christ, and B. Jilma Calcium-channel blockers reduce the antiplatelet effect of clopidogrel J Am Coll Cardiol 52 2008 1557 1563
7. U.S. Tantry, D.J. Kereiakes, and P.A. Gurbel Clopidogrel and proton pump inhibitors: influence of pharmacological interactions on clinical outcomes and mechanistic explanations JACC Cardiovasc Interv 4 2011 365 380
8. J.S. Berger, D.L. Bhatt, S.R. Steinhubl, M. Shao, P.G. Steg, and G. Montalescot Smoking, clopidogrel, and mortality in patients with established cardiovascular disease Circulation 120 2009 2337 2344
9. L. Ang, V. Palakodeti, A. Khalid, S. Tsimikas, Z. Idrees, and P. Tran Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel J Am Coll Cardiol 52 2008 1052 1059
10. J. Silvain, G. Cayla, J.S. Hulot, J. Finzi, M. Kerneis, and S.A. O'Connor High on-thienopyridine platelet reactivity in elderly coronary patients: the SENIOR-PLATELET study Eur Heart J 33 2012 1241 1249
11. L. Bonello, F. Paganelli, M. Arpin-Bornet, P. Auquier, J. Sampol, and F. Dignat-George Vasodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events J Thromb Haemost 5 2007 1630 1636
12. J.M. Siller-Matula, S. Panzer, and B. Jilma Reproducibility and standardized reporting of the vasodilator-stimulated phosphoprotein phosphorylation assay Platelets 19 2008 551 554
13. C. Varenhorst, S. James, D. Erlinge, O.O. Braun, J.T. Brandt, and K.J. Winters Assessment of P2Y(12) inhibition with the point-of-care device VerifyNow P2Y12 in patients treated with prasugrel or clopidogrel coadministered with aspirin Am Heart J 157 562 2009 e561 e569
14. B. Aleil, C. Ravanat, J.P. Cazenave, G. Rochoux, A. Heitz, and C. Gachet Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases J Thromb Haemost 3 2005 85 92
15. R. Blindt, K. Stellbrink, A. de Taeye, R. Muller, P. Kiefer, and E. Yagmur The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis Thromb Haemost 98 2007 1329 1334
16. D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
17. H. Guo, N.T. Ingolia, J.S. Weissman, and D.P. Bartel Mammalian microRNAs predominantly act to decrease target mRNA levels Nature 466 2010 835 840
18. M.R. Fabian, N. Sonenberg, and W. Filipowicz Regulation of mRNA translation and stability by microRNAs Annu Rev Biochem 79 2010 351 379
19. D.P. Bartel MicroRNAs: target recognition and regulatory functions Cell 136 2009 215 233
20. P. Landry, I. Plante, D.L. Ouellet, M.P. Perron, G. Rousseau, and P. Provost Existence of a microRNA pathway in anucleate platelets Nat Struct Mol Biol 16 2009 961 966
21. A.A. Kondkar, M.S. Bray, S.M. Leal, S. Nagalla, D.J. Liu, and Y. Jin VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA J Thromb Haemost 8 2010 369 378
22. C.W. Hamm, J.P. Bassand, S. Agewall, J. Bax, E. Boersma, and H. Bueno ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC) Eur Heart J 32 2011 2999 3054
23. T. Cuisset, C. Frere, J. Quilici, F. Barbou, P.E. Morange, and T. Hovasse High post-treatment platelet reactivity identified low-responders to dual antiplatelet therapy at increased risk of recurrent cardiovascular events after stenting for acute coronary syndrome J Thromb Haemost 4 2006 542 549
24. T. Cuisset, G. Cayla, C. Frere, J. Quilici, R. Poyet, and B. Gaborit Predictive value of post-treatment platelet reactivity for occurrence of post-discharge bleeding after non-ST elevation acute coronary syndrome. Shifting from antiplatelet resistance to bleeding risk assessment? EuroIntervention 5 2009 325 329
25. S. Nagalla, C. Shaw, X. Kong, A.A. Kondkar, L.C. Edelstein, and L. Ma Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity Blood 117 2011 5189 5197
26. G. Sianos, M.A. Morel, A.P. Kappetein, M.C. Morice, A. Colombo, and K. Dawkins The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease EuroIntervention 1 2005 219 227
27. M.P. LaValley Logistic regression Circulation 117 2008 2395 2399
28. P. Schubert, and D.V. Devine De novo protein synthesis in mature platelets: a consideration for transfusion medicine Vox Sang 99 2010 112 122
29. H. Fernando, N. Bassler, J. Habersberger, L.J. Sheffield, R. Sharma, and A.M. Dart Randomized double-blind placebo-controlled crossover study to determine the effects of esomeprazole on inhibition of platelet function by clopidogrel J Thromb Haemost 9 2011 1582 1589
30. R. Paniccia, E. Antonucci, A.M. Gori, R. Marcucci, C. Giglioli, and D. Antoniucci Different methodologies for evaluating the effect of clopidogrel on platelet function in high-risk coronary artery disease patients J Thromb Haemost 5 2007 1839 1847
31. D. Ungar, and F.M. Hughson SNARE protein structure and function Annu Rev Cell Dev Biol 19 2003 493 517
32. I.Y. Oh, K.W. Park, S.H. Kang, J.J. Park, S.H. Na, and H.J. Kang Association of cytochrome P450 2C19*2 polymorphism with clopidogrel response variability and cardiovascular events in Koreans treated with drug-eluting stents Heart 98 2012 139 144
33. Y.H. Jeong, U.S. Tantry, I.S. Kim, J.S. Koh, T.J. Kwon, and Y. Park Effect of CYP2C19*2 and*3 loss-of-function alleles on platelet reactivity and adverse clinical events in East Asian acute myocardial infarction survivors treated with clopidogrel and aspirin Circ Cardiovasc Interv 4 2011 585 594
34. A. Zampetaki, P. Willeit, L. Tilling, I. Drozdov, M. Prokopi, and J.M. Renard Prospective study on circulating MicroRNAs and risk of myocardial infarction J Am Coll Cardiol 60 2012 290 299
35. R.M. O'Connell, J.L. Zhao, and D.S. Rao MicroRNA function in myeloid biology Blood 118 2011 2960 2969